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The map label for this gene is tldD [H]

Identifier: 59710986

GI number: 59710986

Start: 413840

End: 415285

Strand: Direct

Name: tldD [H]

Synonym: VF_0379

Alternate gene names: 59710986

Gene position: 413840-415285 (Clockwise)

Preceding gene: 59710985

Following gene: 59710988

Centisome position: 14.28

GC content: 42.88

Gene sequence:

>1446_bases
ATGAGTTTGCAAGAAGTAGAACAATCCTTATTGAGTCAAGCAGGGATCGGTCAGCAGGAACTGTCTCAGACCTTAAGCAC
CATCGCAAAACGAGACGTAGACTACGCTGATATCTACTTTCAATCATGTTGGCATGAGTCATTGGTACTTGAAGACAGTA
TTATTAAAGATGGGTCTTTTAATATTGACCGTGGTGTTGGCATTCGAGCTGTTGCTGGAGAAAAAACAGGGTTTGCTTAT
TCAGATCAAATTAATCTTGAAGCATTAACTCAAAGTGCTAGAGCGGCTCGTGGTATCGTTCAGCAAGGTGGTGAAGGCAA
AGTTAAGGCATTCTCATCGCAGTCTATTCCTCAATTTTATCAGCCTGTAAATCCGTTAAATAGTTTAGATAAGCAACAGA
AGATCGCATTGCTTGAGGAGATCGACGCTTATATTCGAGCGAAAGAACCACTAGTTCAAGAAGTGTCTGCAAGCATAAGT
GGTGTTTATGAGCAAATGCTTGTTGCAGCTTTAGATGGTACCTATGCTGCCGATATTCGTCCATTGGTACGCCTTTCTAT
TAGCGTATTAGTTCAGCGTGGTGATAAGCGTGAACGTGGTAGCGCTGGTGGTGGTGGCCGCTATGGTTATGATTACTTCT
TAACAGAAGTGAATGGTAAATCTATTGCGCTAGAGTTTGCTGATGAAGCGATTCGTCAAGCATTAGTTAATCTTGATGCT
GACGCAGCACCTGCTGGTATGATGCCTGTCGTTCTTGGTTCTGGCTGGCCGGGAGTTTTATTGCATGAAGCAGTAGGACA
CGGTCTTGAAGGTGACTTTAACCGTAAAGGTTCGTCAGTATTTGCTGGTAAAGTTGGAGAGAAAGTAACGTCTTCTGTAT
GTACTATTGTTGACGATGGCACTATGGTTGATCGCCGTGGTTCATTAAATGTCGATGATGAAGGTGTTCCAGGGCAATAC
AATACACTAATTGAAAATGGTGTATTAAAAGGCTACATGCAAGATAAACTTAATGCTCGATTAATGGGTGTTGCACCTAC
AGGTAATGGTCGTCGTGAGTCTTACGCACATTTACCAATGCCTCGTATGACAAATACTTATATGCTGCCTGGTGAGTATG
CTCCTGAAGAAATCATCTCAACGGTTAAAAAAGGTATTTATGCGCCTAACTTTGGTGGTGGCCAAGTAGATATTACCTCT
GGTAAGTTTGTTTTCTCTGCATCAGAAGCGTATTTAATTGAAGATGGTAAAATTACTCGCCCAGTAAAAGGGGCAACCTT
AATCGGATCTGGCATCGAAGCAATGCAGCAAATCTCGATGGTTGGTAATGATTTATCACTCGATCGTGGTGTCGGTGTGT
GTGGCAAAGCTGGCCAGAGCGTACCTGTTGGTGTTGGTCAACCAACGCTAAAACTAGATGCGTTAACGGTTGGTGGTACA
GAGTAA

Upstream 100 bases:

>100_bases
ACCTTAAATACAGAAAAGAGTGAGTTTAGCCTATAAAACTCACTCTTTTTTCTTCATAATTAAACGATAGATTTTCAATT
CTTAAAAAAGAGTATTCCTA

Downstream 100 bases:

>100_bases
TACTAATACTGACAACAAAATGAATAAAAAAAGAGCCAAGGATCATTAAGATGCTTGGCTTTTTTATTAACAAAAATATG
AATTCAAAAGAATTACAGAT

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLQEVEQSLLSQAGIGQQELSQTLSTIAKRDVDYADIYFQSCWHESLVLEDSIIKDGSFNIDRGVGIRAVAGEKTGFAY
SDQINLEALTQSARAARGIVQQGGEGKVKAFSSQSIPQFYQPVNPLNSLDKQQKIALLEEIDAYIRAKEPLVQEVSASIS
GVYEQMLVAALDGTYAADIRPLVRLSISVLVQRGDKRERGSAGGGGRYGYDYFLTEVNGKSIALEFADEAIRQALVNLDA
DAAPAGMMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGEKVTSSVCTIVDDGTMVDRRGSLNVDDEGVPGQY
NTLIENGVLKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEYAPEEIISTVKKGIYAPNFGGGQVDITS
GKFVFSASEAYLIEDGKITRPVKGATLIGSGIEAMQQISMVGNDLSLDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
E

Sequences:

>Translated_481_residues
MSLQEVEQSLLSQAGIGQQELSQTLSTIAKRDVDYADIYFQSCWHESLVLEDSIIKDGSFNIDRGVGIRAVAGEKTGFAY
SDQINLEALTQSARAARGIVQQGGEGKVKAFSSQSIPQFYQPVNPLNSLDKQQKIALLEEIDAYIRAKEPLVQEVSASIS
GVYEQMLVAALDGTYAADIRPLVRLSISVLVQRGDKRERGSAGGGGRYGYDYFLTEVNGKSIALEFADEAIRQALVNLDA
DAAPAGMMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGEKVTSSVCTIVDDGTMVDRRGSLNVDDEGVPGQY
NTLIENGVLKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEYAPEEIISTVKKGIYAPNFGGGQVDITS
GKFVFSASEAYLIEDGKITRPVKGATLIGSGIEAMQQISMVGNDLSLDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
E
>Mature_480_residues
SLQEVEQSLLSQAGIGQQELSQTLSTIAKRDVDYADIYFQSCWHESLVLEDSIIKDGSFNIDRGVGIRAVAGEKTGFAYS
DQINLEALTQSARAARGIVQQGGEGKVKAFSSQSIPQFYQPVNPLNSLDKQQKIALLEEIDAYIRAKEPLVQEVSASISG
VYEQMLVAALDGTYAADIRPLVRLSISVLVQRGDKRERGSAGGGGRYGYDYFLTEVNGKSIALEFADEAIRQALVNLDAD
AAPAGMMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGEKVTSSVCTIVDDGTMVDRRGSLNVDDEGVPGQYN
TLIENGVLKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEYAPEEIISTVKKGIYAPNFGGGQVDITSG
KFVFSASEAYLIEDGKITRPVKGATLIGSGIEAMQQISMVGNDLSLDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGTE

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=480, Percent_Identity=69.5833333333333, Blast_Score=669, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51244; Mature: 51112

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQEVEQSLLSQAGIGQQELSQTLSTIAKRDVDYADIYFQSCWHESLVLEDSIIKDGSF
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECHHHCCCCCC
NIDRGVGIRAVAGEKTGFAYSDQINLEALTQSARAARGIVQQGGEGKVKAFSSQSIPQFY
CCCCCCCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
QPVNPLNSLDKQQKIALLEEIDAYIRAKEPLVQEVSASISGVYEQMLVAALDGTYAADIR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PLVRLSISVLVQRGDKRERGSAGGGGRYGYDYFLTEVNGKSIALEFADEAIRQALVNLDA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEHHHHHHHHHHHHHCCC
DAAPAGMMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGEKVTSSVCTIVDDG
CCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHEEEECC
TMVDRRGSLNVDDEGVPGQYNTLIENGVLKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLPGEYAPEEIISTVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIEDGKITR
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIEAMQQISMVGNDLSLDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
CCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
E
C
>Mature Secondary Structure 
SLQEVEQSLLSQAGIGQQELSQTLSTIAKRDVDYADIYFQSCWHESLVLEDSIIKDGSF
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECHHHCCCCCC
NIDRGVGIRAVAGEKTGFAYSDQINLEALTQSARAARGIVQQGGEGKVKAFSSQSIPQFY
CCCCCCCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHH
QPVNPLNSLDKQQKIALLEEIDAYIRAKEPLVQEVSASISGVYEQMLVAALDGTYAADIR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PLVRLSISVLVQRGDKRERGSAGGGGRYGYDYFLTEVNGKSIALEFADEAIRQALVNLDA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEHHHHHHHHHHHHHCCC
DAAPAGMMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGEKVTSSVCTIVDDG
CCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHEEEECC
TMVDRRGSLNVDDEGVPGQYNTLIENGVLKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLPGEYAPEEIISTVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIEDGKITR
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIEAMQQISMVGNDLSLDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
CCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]