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The map label for this gene is malZ [H]

Identifier: 172087750

GI number: 172087750

Start: 2280648

End: 2282480

Strand: Direct

Name: malZ [H]

Synonym: VF_2049

Alternate gene names: 172087750

Gene position: 2280648-2282480 (Clockwise)

Preceding gene: 59712655

Following gene: 59712658

Centisome position: 78.71

GC content: 40.86

Gene sequence:

>1833_bases
ATGATTACAAAAGCAGCGATTTATCATCGATCTCACTCTAGTTATTCTTATGCATATGATAAGGATACGCTTCATTTGCG
AATTCGTACCGCAAAAGGAGAAGTAGACAATGCGACGCTAAGAATTGGCGACCCATACGATTGGACTTTTGGTGGCGGTG
GCGGCAATTTAAATGCTGAAGACGCAAGCGGCTGGACAGGTGGAACCAACTTACCCATGATAAAAGAGTGTGAAACAGAA
CTGTTTGACTACTGGTTTTGTGAAGCACAACCTCGCTTTTATCGTGCACGTTACGCTTTCCTTCTTGAAGGCAAAGACAG
TGAAAAATTACTGGTAAGCGAAAAACTCATCACCCAAATAACCGATGACGCCGATCCAATACTCAGTCAATTACTGAATT
TTTATTGCTTCCCATACATGAACCCAACTGATGTGTTTAACGCACCAGAATGGGTTAAAGAAACCATTTGGTATCAAATT
TTCCCAGAGCGTTTTGCTAATGGTGACCCATCTATCTCACCAAAAAATGTACTGCCTTGGGGATCTGAAGATCCAAAAAC
CAACAGTTTCTTTGGTGGCGATTTACAAGGGGTTATTGATCATCTTGATTACCTGCAAGATCTCGGTATTACTGGTATTT
ATTTCACACCTATCACTCAAGGTGAAACGAACCATAAATACGACACCACCGATTATTTAAAAGTAGACCCCGCTTTTGGT
AGTGATGAAACGGTTCATACTTTAATAGATGAAGCACATAAACGTGGCATGAAAGTCATGCTAGATGCGGTATTTAATCA
TATCGGTGCTAATTCAATTCAGTGGCAAGATGTCATTAAACATGGAAAAGACTCTCAATACATCGATTGGTTTTATGTCG
AGCAATTTCCACTGATTGATGAGTCAAAAAAAGCGTACCACAGTAAAGAGCAATTAAATTATCGTGCCTTTGCTTTTGCG
CAAAACATGCCAAAACTCAATACAGAAAATCCAGAAGTGATTGAATACCTAATTGAAGTTGGCCGCTACTGGGTGAAAAA
CTTTGACATTGATGCATGGCGTTTAGATGTAGCAAACGAAGTTGATCAACGTTTTTGGCGACGCTTCCGTGATGAACTAA
AAGCCATCAAACCTGAGTTATATATTTTAGGTGAAGTGTGGCACGACTCAATGAACTGGCTAGGTGGTGATCAGTTTGAT
GGCGTAATGAATTACCCATTAGCGGATGCCATGTTAGGCTTTTTTGCCCATGACAACCTAAGTGCAAATCAGTTTAAATT
TGCGGTAAATGACGTTAATGCCAACTACCCTATTAACGTGAATGAAGTGGCCTTTTCATTACTTGATAGCCACGATACAC
CACGCATTATTAACCGATGCAACGGCAATAAAGAGAAAGCGAAGTTAGCCTATTTGTTCCAATTCACTCACAGTGGTACG
CCTTGTATTTATTACGGTGGTGAAATTGGGCTAGATGGCGGTGTTGATCCGCTTAACCGAAAATGCATGATTTGGGATGA
ACGTCAGCATGATATGAACATGAAACATCACATCATGCAGCTCATCAAACTGCGTAAAGCTCACCCAGCGTTACGTGCTC
ATGCCATAAACTGGCTTGTGGTTGACGATGAACAACAGTGCTTTATCTACCAAAAAGAATATCAGGGTGAACGTATTATT
ATTGCTATGAACAACAGTAATGCCCCCGCTTGTATGACGCTTCCTAGTGAGTGGCGTGATCAAGAGGTCACCGATATTTA
TCATGAAACCGCCGTTAAATTAACGCAAAGTTTGACGGTGCCTGCATTTGGCTTTGCTGTTTATCAGATTTAA

Upstream 100 bases:

>100_bases
TTTTGCTCAAGCTTGGAGCGTCAGCGAAGTGTTACGTGTTCTTAAACATTATGAAGAACGTATCTAACCATTACGAACTT
AACGCTAAACGGTATTAATA

Downstream 100 bases:

>100_bases
ACGCTATAAGTAGCAATGTATTGATAAGAAACATAAAATAGCTCTTTTCGATTAGTCTGAAGAGCTATTATGTTTAAATT
AATGCTTCAATTCATACAAG

Product: maltodextrin glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MITKAAIYHRSHSSYSYAYDKDTLHLRIRTAKGEVDNATLRIGDPYDWTFGGGGGNLNAEDASGWTGGTNLPMIKECETE
LFDYWFCEAQPRFYRARYAFLLEGKDSEKLLVSEKLITQITDDADPILSQLLNFYCFPYMNPTDVFNAPEWVKETIWYQI
FPERFANGDPSISPKNVLPWGSEDPKTNSFFGGDLQGVIDHLDYLQDLGITGIYFTPITQGETNHKYDTTDYLKVDPAFG
SDETVHTLIDEAHKRGMKVMLDAVFNHIGANSIQWQDVIKHGKDSQYIDWFYVEQFPLIDESKKAYHSKEQLNYRAFAFA
QNMPKLNTENPEVIEYLIEVGRYWVKNFDIDAWRLDVANEVDQRFWRRFRDELKAIKPELYILGEVWHDSMNWLGGDQFD
GVMNYPLADAMLGFFAHDNLSANQFKFAVNDVNANYPINVNEVAFSLLDSHDTPRIINRCNGNKEKAKLAYLFQFTHSGT
PCIYYGGEIGLDGGVDPLNRKCMIWDERQHDMNMKHHIMQLIKLRKAHPALRAHAINWLVVDDEQQCFIYQKEYQGERII
IAMNNSNAPACMTLPSEWRDQEVTDIYHETAVKLTQSLTVPAFGFAVYQI

Sequences:

>Translated_610_residues
MITKAAIYHRSHSSYSYAYDKDTLHLRIRTAKGEVDNATLRIGDPYDWTFGGGGGNLNAEDASGWTGGTNLPMIKECETE
LFDYWFCEAQPRFYRARYAFLLEGKDSEKLLVSEKLITQITDDADPILSQLLNFYCFPYMNPTDVFNAPEWVKETIWYQI
FPERFANGDPSISPKNVLPWGSEDPKTNSFFGGDLQGVIDHLDYLQDLGITGIYFTPITQGETNHKYDTTDYLKVDPAFG
SDETVHTLIDEAHKRGMKVMLDAVFNHIGANSIQWQDVIKHGKDSQYIDWFYVEQFPLIDESKKAYHSKEQLNYRAFAFA
QNMPKLNTENPEVIEYLIEVGRYWVKNFDIDAWRLDVANEVDQRFWRRFRDELKAIKPELYILGEVWHDSMNWLGGDQFD
GVMNYPLADAMLGFFAHDNLSANQFKFAVNDVNANYPINVNEVAFSLLDSHDTPRIINRCNGNKEKAKLAYLFQFTHSGT
PCIYYGGEIGLDGGVDPLNRKCMIWDERQHDMNMKHHIMQLIKLRKAHPALRAHAINWLVVDDEQQCFIYQKEYQGERII
IAMNNSNAPACMTLPSEWRDQEVTDIYHETAVKLTQSLTVPAFGFAVYQI
>Mature_610_residues
MITKAAIYHRSHSSYSYAYDKDTLHLRIRTAKGEVDNATLRIGDPYDWTFGGGGGNLNAEDASGWTGGTNLPMIKECETE
LFDYWFCEAQPRFYRARYAFLLEGKDSEKLLVSEKLITQITDDADPILSQLLNFYCFPYMNPTDVFNAPEWVKETIWYQI
FPERFANGDPSISPKNVLPWGSEDPKTNSFFGGDLQGVIDHLDYLQDLGITGIYFTPITQGETNHKYDTTDYLKVDPAFG
SDETVHTLIDEAHKRGMKVMLDAVFNHIGANSIQWQDVIKHGKDSQYIDWFYVEQFPLIDESKKAYHSKEQLNYRAFAFA
QNMPKLNTENPEVIEYLIEVGRYWVKNFDIDAWRLDVANEVDQRFWRRFRDELKAIKPELYILGEVWHDSMNWLGGDQFD
GVMNYPLADAMLGFFAHDNLSANQFKFAVNDVNANYPINVNEVAFSLLDSHDTPRIINRCNGNKEKAKLAYLFQFTHSGT
PCIYYGGEIGLDGGVDPLNRKCMIWDERQHDMNMKHHIMQLIKLRKAHPALRAHAINWLVVDDEQQCFIYQKEYQGERII
IAMNNSNAPACMTLPSEWRDQEVTDIYHETAVKLTQSLTVPAFGFAVYQI

Specific function: Hydrolyzes pullulan efficiently but only a small amount of starch. Endohydrolysis of 1,4-alpha-glucosidic linkages in pullulan to form panose. Cleaves also (1-6)-alpha-glucosidic linkages to form maltotriose [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=398, Percent_Identity=23.3668341708543, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1786604, Length=465, Percent_Identity=29.8924731182796, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI1790687, Length=394, Percent_Identity=25.8883248730964, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1789995, Length=145, Percent_Identity=33.1034482758621, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322245, Length=236, Percent_Identity=28.8135593220339, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319776, Length=404, Percent_Identity=24.009900990099, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321731, Length=404, Percent_Identity=23.7623762376238, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321726, Length=231, Percent_Identity=27.7056277056277, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322241, Length=231, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6322021, Length=231, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324416, Length=231, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330053, Length=193, Percent_Identity=31.6062176165803, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583745, Length=403, Percent_Identity=24.8138957816377, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583747, Length=232, Percent_Identity=28.0172413793103, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24583749, Length=232, Percent_Identity=28.0172413793103, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24586587, Length=229, Percent_Identity=25.3275109170306, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24586599, Length=225, Percent_Identity=27.1111111111111, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24586591, Length=227, Percent_Identity=26.8722466960352, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45549022, Length=246, Percent_Identity=27.6422764227642, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24586593, Length=436, Percent_Identity=23.394495412844, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24586589, Length=221, Percent_Identity=27.1493212669683, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.135 [H]

Molecular weight: Translated: 70386; Mature: 70386

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITKAAIYHRSHSSYSYAYDKDTLHLRIRTAKGEVDNATLRIGDPYDWTFGGGGGNLNAE
CCCCEEEEECCCCCCEEEECCCEEEEEEEECCCCCCCCEEEECCCCCEEECCCCCCCCCC
DASGWTGGTNLPMIKECETELFDYWFCEAQPRFYRARYAFLLEGKDSEKLLVSEKLITQI
CCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHH
TDDADPILSQLLNFYCFPYMNPTDVFNAPEWVKETIWYQIFPERFANGDPSISPKNVLPW
CCCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHEECHHHHCCCCCCCCCCCCCCC
GSEDPKTNSFFGGDLQGVIDHLDYLQDLGITGIYFTPITQGETNHKYDTTDYLKVDPAFG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCC
SDETVHTLIDEAHKRGMKVMLDAVFNHIGANSIQWQDVIKHGKDSQYIDWFYVEQFPLID
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEEEEECCCCC
ESKKAYHSKEQLNYRAFAFAQNMPKLNTENPEVIEYLIEVGRYWVKNFDIDAWRLDVANE
CHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHH
VDQRFWRRFRDELKAIKPELYILGEVWHDSMNWLGGDQFDGVMNYPLADAMLGFFAHDNL
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCC
SANQFKFAVNDVNANYPINVNEVAFSLLDSHDTPRIINRCNGNKEKAKLAYLFQFTHSGT
CCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCHHHHEEEEEEEEECCCC
PCIYYGGEIGLDGGVDPLNRKCMIWDERQHDMNMKHHIMQLIKLRKAHPALRAHAINWLV
CEEEECCEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEE
VDDEQQCFIYQKEYQGERIIIAMNNSNAPACMTLPSEWRDQEVTDIYHETAVKLTQSLTV
ECCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHCCC
PAFGFAVYQI
CHHCEEEEEC
>Mature Secondary Structure
MITKAAIYHRSHSSYSYAYDKDTLHLRIRTAKGEVDNATLRIGDPYDWTFGGGGGNLNAE
CCCCEEEEECCCCCCEEEECCCEEEEEEEECCCCCCCCEEEECCCCCEEECCCCCCCCCC
DASGWTGGTNLPMIKECETELFDYWFCEAQPRFYRARYAFLLEGKDSEKLLVSEKLITQI
CCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHH
TDDADPILSQLLNFYCFPYMNPTDVFNAPEWVKETIWYQIFPERFANGDPSISPKNVLPW
CCCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHEECHHHHCCCCCCCCCCCCCCC
GSEDPKTNSFFGGDLQGVIDHLDYLQDLGITGIYFTPITQGETNHKYDTTDYLKVDPAFG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCC
SDETVHTLIDEAHKRGMKVMLDAVFNHIGANSIQWQDVIKHGKDSQYIDWFYVEQFPLID
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEEEEECCCCC
ESKKAYHSKEQLNYRAFAFAQNMPKLNTENPEVIEYLIEVGRYWVKNFDIDAWRLDVANE
CHHHHHHHHHHCCHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHH
VDQRFWRRFRDELKAIKPELYILGEVWHDSMNWLGGDQFDGVMNYPLADAMLGFFAHDNL
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCC
SANQFKFAVNDVNANYPINVNEVAFSLLDSHDTPRIINRCNGNKEKAKLAYLFQFTHSGT
CCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCHHHHEEEEEEEEECCCC
PCIYYGGEIGLDGGVDPLNRKCMIWDERQHDMNMKHHIMQLIKLRKAHPALRAHAINWLV
CEEEECCEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEE
VDDEQQCFIYQKEYQGERIIIAMNNSNAPACMTLPSEWRDQEVTDIYHETAVKLTQSLTV
ECCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHCCC
PAFGFAVYQI
CHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2482332; 12547200 [H]