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The map label for this gene is abgR [H]

Identifier: 59712658

GI number: 59712658

Start: 2282550

End: 2283485

Strand: Direct

Name: abgR [H]

Synonym: VF_2051

Alternate gene names: 59712658

Gene position: 2282550-2283485 (Clockwise)

Preceding gene: 172087750

Following gene: 59712660

Centisome position: 78.78

GC content: 39.32

Gene sequence:

>936_bases
ATGTTTAAATTAATGCTTCAATTCATACAAGTTGCAAAAGCACAAAATGTTACGCAAGCAGCGAACACCTTGTGCTTAAG
CCAACCGACGTTAAGTCATAATATGCAAAAGCTAGAGGAAAAGCTGGGAAGCAAACTGTTTTATCGCAATTCAAAAGGGA
TCACCCTTACCTCTAGTGGCGAAGTGCTCTACGAGCAAGCTAAAATGATGCAGCATTTATACGAAAATACCCTTCATAAA
TTAGAAAAAAATAAGTTACGGCACCAAACGGAATTAAAAATTGGTTGCGGTGATGCTTGGTGGCATCTATTTGTTCGGGA
CTGTGTTCAAGATTTTAGAGATACCAACCCTCACAGCAATATCACCATTGATGTAGGTGACCACTTGCAGTTAATGAACC
TGCTCCTCAGTGATGAAATCAGCATTTTTGTCGGCCATGAAATATTAGGTCTGGCTCAATACGAAGATATCCTTTTCCAC
CCTCTATTTAGTAGTCATGAAGAAGTGTATGTTCGAAAAGATCATCCACTCTTAGAGCGAGTGTGTAGTGACGAAGATAT
TGCCCGTTTTCCTTCAGTTGATTTAGGGGCATCAAAAAAACGCTATGCGCATCTCGTGCAACAACAAAACAATGAATTAA
GTACCTTTCAAAAACGACACTACCTGCAAGAAAAGGTGATTTACAACACCAACTCCTTATTAACGGCGCTTGATTTACTG
CAAAATAGTGACGCTATTTTGCCTTACCCAGTCGGCATGAAAGTGTATTTTGAAGGCTTTGGGATTGTGCCGTTAAAAAT
GAAGAAGTGCTTTGGTAAAGCGACGATTGGCGCTTATCTGCATAAAGATGGCCAGCAAAATAAACAAAGTATAGCGCTAC
TAGAACAATTTAAAGAGCTCATAAAAAACAACCCTCAAATTAAGGGCAAAGAATAG

Upstream 100 bases:

>100_bases
TGCATTTGGCTTTGCTGTTTATCAGATTTAAACGCTATAAGTAGCAATGTATTGATAAGAAACATAAAATAGCTCTTTTC
GATTAGTCTGAAGAGCTATT

Downstream 100 bases:

>100_bases
AAACAATAAAGCCCAGAGCAGTACATATCTGGGCTTTTACTAGATTAACCGATATCTAATATTGCAGAAGCGATAGCAAA
ATAAATCAATACACCAGAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MFKLMLQFIQVAKAQNVTQAANTLCLSQPTLSHNMQKLEEKLGSKLFYRNSKGITLTSSGEVLYEQAKMMQHLYENTLHK
LEKNKLRHQTELKIGCGDAWWHLFVRDCVQDFRDTNPHSNITIDVGDHLQLMNLLLSDEISIFVGHEILGLAQYEDILFH
PLFSSHEEVYVRKDHPLLERVCSDEDIARFPSVDLGASKKRYAHLVQQQNNELSTFQKRHYLQEKVIYNTNSLLTALDLL
QNSDAILPYPVGMKVYFEGFGIVPLKMKKCFGKATIGAYLHKDGQQNKQSIALLEQFKELIKNNPQIKGKE

Sequences:

>Translated_311_residues
MFKLMLQFIQVAKAQNVTQAANTLCLSQPTLSHNMQKLEEKLGSKLFYRNSKGITLTSSGEVLYEQAKMMQHLYENTLHK
LEKNKLRHQTELKIGCGDAWWHLFVRDCVQDFRDTNPHSNITIDVGDHLQLMNLLLSDEISIFVGHEILGLAQYEDILFH
PLFSSHEEVYVRKDHPLLERVCSDEDIARFPSVDLGASKKRYAHLVQQQNNELSTFQKRHYLQEKVIYNTNSLLTALDLL
QNSDAILPYPVGMKVYFEGFGIVPLKMKKCFGKATIGAYLHKDGQQNKQSIALLEQFKELIKNNPQIKGKE
>Mature_311_residues
MFKLMLQFIQVAKAQNVTQAANTLCLSQPTLSHNMQKLEEKLGSKLFYRNSKGITLTSSGEVLYEQAKMMQHLYENTLHK
LEKNKLRHQTELKIGCGDAWWHLFVRDCVQDFRDTNPHSNITIDVGDHLQLMNLLLSDEISIFVGHEILGLAQYEDILFH
PLFSSHEEVYVRKDHPLLERVCSDEDIARFPSVDLGASKKRYAHLVQQQNNELSTFQKRHYLQEKVIYNTNSLLTALDLL
QNSDAILPYPVGMKVYFEGFGIVPLKMKKCFGKATIGAYLHKDGQQNKQSIALLEQFKELIKNNPQIKGKE

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=23.8095238095238, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=22.8373702422145, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367136, Length=121, Percent_Identity=30.5785123966942, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789506, Length=299, Percent_Identity=20.066889632107, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786713, Length=197, Percent_Identity=24.8730964467005, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693105, Length=176, Percent_Identity=23.8636363636364, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35791; Mature: 35791

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKLMLQFIQVAKAQNVTQAANTLCLSQPTLSHNMQKLEEKLGSKLFYRNSKGITLTSSG
CHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCC
EVLYEQAKMMQHLYENTLHKLEKNKLRHQTELKIGCGDAWWHLFVRDCVQDFRDTNPHSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCE
ITIDVGDHLQLMNLLLSDEISIFVGHEILGLAQYEDILFHPLFSSHEEVYVRKDHPLLER
EEEECCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
VCSDEDIARFPSVDLGASKKRYAHLVQQQNNELSTFQKRHYLQEKVIYNTNSLLTALDLL
HCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QNSDAILPYPVGMKVYFEGFGIVPLKMKKCFGKATIGAYLHKDGQQNKQSIALLEQFKEL
CCCCCEEECCCCCEEEECCCCCCHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IKNNPQIKGKE
HHCCCCCCCCC
>Mature Secondary Structure
MFKLMLQFIQVAKAQNVTQAANTLCLSQPTLSHNMQKLEEKLGSKLFYRNSKGITLTSSG
CHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEECCC
EVLYEQAKMMQHLYENTLHKLEKNKLRHQTELKIGCGDAWWHLFVRDCVQDFRDTNPHSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCE
ITIDVGDHLQLMNLLLSDEISIFVGHEILGLAQYEDILFHPLFSSHEEVYVRKDHPLLER
EEEECCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
VCSDEDIARFPSVDLGASKKRYAHLVQQQNNELSTFQKRHYLQEKVIYNTNSLLTALDLL
HCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QNSDAILPYPVGMKVYFEGFGIVPLKMKKCFGKATIGAYLHKDGQQNKQSIALLEQFKEL
CCCCCEEECCCCCEEEECCCCCCHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IKNNPQIKGKE
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]