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The map label for this gene is prkA [H]

Identifier: 172087726

GI number: 172087726

Start: 1997706

End: 1999640

Strand: Direct

Name: prkA [H]

Synonym: VF_1771

Alternate gene names: 172087726

Gene position: 1997706-1999640 (Clockwise)

Preceding gene: 59712377

Following gene: 59712380

Centisome position: 68.94

GC content: 38.86

Gene sequence:

>1935_bases
ATGAGTATTTTTGACCACTATCAAGCCCGTTATGAAGCGGCAAAAGATGAAGAGATGTCACTGCAAGATTTCTTATCACT
ATGTAGTAATGACAAAAGTGCTTATGCTAATGCAGCAGAAAGACTACTGCTAGCCATTGGAGAGCCTGAGATCATCGATA
CTGCACTTGATCCGCAACTCAGTCGCATTTTCTCTAATCGTGTTATTTCTCGCTATGAAACCTTCAAAGATTTCTATGGT
ATGGAAGAACCAATAGAACAAATTGTTTCTTACTTAAAGCATGCTGCTCAAGGTCTTGAAGAGCGTAAGCAAGTGCTTTA
TTTATTAGGCCCAGTAGGCGGTGGTAAGTCTTCACTTGCTGAAAAACTAAAAAGCTTAATGCAAAAATTACCTATTTATG
TACTTAGCGCAAATGGGGAACGCAGCCCAGTTAACGATCACCCTTTCTGTTTATTTGATGTCTATGAAGATGGTGAACTA
CTCAAAAACGAGTACGGTATTGAACCACGTAACCTACGCTCCATTATGTCTCCTTGGGCAGCAAAACGACTGCATGAATT
TGGTGGCGACATAACAAAATTTAAAGTCATTAAAGTTCACCCATCGATTCTTGACCAAATTGGTATCGCGAAAACGGAAC
CTGGCGATGAAAATAATCAAGACATTTCCTCTCTTGTAGGTAAGGTCGATATTCGTCAATTAGAGCATTTCGCCCAAGAT
GATCCTGATGCTTATAGCTATTCGGGGTCACTATGTAAAGCGAACCAAGGCCTAATGGAATTCGTAGAGATGTTTAAGGC
TCCGATTAAAGTGCTTCATCCTCTTTTAACTGCAACCCAAGAAGGTAACTTTAATGGGACAGAAGGACTGTCAGCGTTAC
CATTTGATGGGATGATCCTTGCTCACTCAAACGAATCAGAGTGGCAAACGTTCCGAAATAACAAAAACAACGAAGCCTTT
TTAGATAGGGTTTATATCGTAAAAGTCCCTTATTGTTTACGTGTATCGGAAGAAATGAAGATATACCAAAAACTACTAGA
ACACAGTGAATTGTCTCATGCTCCTTGCTCTCCTAGTACATTGGATATTCTGGCGCAATTCTCAATATTATCGCGTCTAA
AAGAACCAGAGAATTCATCTCTCTTCTCTAAAATGCGAGTTTATGACGGTGAAACCCTAAAAGACACCGATCCAAAAGCC
AAAAGTTACCAAGAGTATCGAGATTTTGCTGGTGTTGATGAAGGTATGTCAGGCTTATCAACTCGATTCGCCTTTAAGAT
CCTCTCTCGTGTATTTAACTTTGATCAAACCGAAGTCGCAGCCAACCCTGTTCATCTTTTTTATGTAATAGAACAACAAA
TAGAAAGAGAGCAATTTGCGCAAGACATTGCAGATAAATACACCGAGTTCTTAAAAGGGTTCCTAATCCCTAAATATGTC
GAGTTTATCGGAAAAGAAATTCAAACCGCTTATCTTGAATCTTATTCAGAATATGGTCAGAACATTTTCGACCGTTACGT
AACCTATGCTGATTTTTGGATTCAAGATCAAGAGTATCGTGACCCTGAAACTGGCCAATTATTTGACCGTTCAGCACTTA
ACGATGAATTAGAAAAAATAGAAAAAACAGCCGGGATCAGCAATCCAAAAGATTTCCGTAATGAAATCGTGAATTTTGTT
CTTAGAGCAAAAGCAAACAACAACGGACAAAACCCAACCTGGACCAGTTACGAAAAACTGCGTGTAGTTATTGAGAAGAA
AATGTTCTCCAATACAGAAGATCTTCTTCCAGTTATCTCCTTTAACGGAAAAACCTCAACCGACGATCAGAAAAAACATG
ATGATTTTGTAGCTCGAATGATGGAAAAAGGCTACACCAAAAAACAAGTAAGACTATTAGCTGAATGGTACTTACGTGTT
CGTAAATCATCATAA

Upstream 100 bases:

>100_bases
AATTTCACTCTATTTTCAGTTTTTTCTTGGACAAAATAAGCATTTAGTTACTAGGCTTAGTATGCGTAATTTAAAAAACG
GATGACAAGAGGAAATGGAT

Downstream 100 bases:

>100_bases
AAATAAACAGGACGTTACAGCCCATAGCTGATTATGGGCTGATCTAATAACATTTTAGCTAATTTGTTGTCTATATAAGT
AAGTTCCTTTAGACAATCGC

Product: serine kinase PrkA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MSIFDHYQARYEAAKDEEMSLQDFLSLCSNDKSAYANAAERLLLAIGEPEIIDTALDPQLSRIFSNRVISRYETFKDFYG
MEEPIEQIVSYLKHAAQGLEERKQVLYLLGPVGGGKSSLAEKLKSLMQKLPIYVLSANGERSPVNDHPFCLFDVYEDGEL
LKNEYGIEPRNLRSIMSPWAAKRLHEFGGDITKFKVIKVHPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMILAHSNESEWQTFRNNKNNEAF
LDRVYIVKVPYCLRVSEEMKIYQKLLEHSELSHAPCSPSTLDILAQFSILSRLKEPENSSLFSKMRVYDGETLKDTDPKA
KSYQEYRDFAGVDEGMSGLSTRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDIADKYTEFLKGFLIPKYV
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRSALNDELEKIEKTAGISNPKDFRNEIVNFV
LRAKANNNGQNPTWTSYEKLRVVIEKKMFSNTEDLLPVISFNGKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRV
RKSS

Sequences:

>Translated_644_residues
MSIFDHYQARYEAAKDEEMSLQDFLSLCSNDKSAYANAAERLLLAIGEPEIIDTALDPQLSRIFSNRVISRYETFKDFYG
MEEPIEQIVSYLKHAAQGLEERKQVLYLLGPVGGGKSSLAEKLKSLMQKLPIYVLSANGERSPVNDHPFCLFDVYEDGEL
LKNEYGIEPRNLRSIMSPWAAKRLHEFGGDITKFKVIKVHPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMILAHSNESEWQTFRNNKNNEAF
LDRVYIVKVPYCLRVSEEMKIYQKLLEHSELSHAPCSPSTLDILAQFSILSRLKEPENSSLFSKMRVYDGETLKDTDPKA
KSYQEYRDFAGVDEGMSGLSTRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDIADKYTEFLKGFLIPKYV
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRSALNDELEKIEKTAGISNPKDFRNEIVNFV
LRAKANNNGQNPTWTSYEKLRVVIEKKMFSNTEDLLPVISFNGKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRV
RKSS
>Mature_643_residues
SIFDHYQARYEAAKDEEMSLQDFLSLCSNDKSAYANAAERLLLAIGEPEIIDTALDPQLSRIFSNRVISRYETFKDFYGM
EEPIEQIVSYLKHAAQGLEERKQVLYLLGPVGGGKSSLAEKLKSLMQKLPIYVLSANGERSPVNDHPFCLFDVYEDGELL
KNEYGIEPRNLRSIMSPWAAKRLHEFGGDITKFKVIKVHPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQDD
PDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMILAHSNESEWQTFRNNKNNEAFL
DRVYIVKVPYCLRVSEEMKIYQKLLEHSELSHAPCSPSTLDILAQFSILSRLKEPENSSLFSKMRVYDGETLKDTDPKAK
SYQEYRDFAGVDEGMSGLSTRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDIADKYTEFLKGFLIPKYVE
FIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRSALNDELEKIEKTAGISNPKDFRNEIVNFVL
RAKANNNGQNPTWTSYEKLRVVIEKKMFSNTEDLLPVISFNGKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRVR
KSS

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=644, Percent_Identity=83.695652173913, Blast_Score=1155, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 73929; Mature: 73798

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFDHYQARYEAAKDEEMSLQDFLSLCSNDKSAYANAAERLLLAIGEPEIIDTALDPQL
CCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
SRIFSNRVISRYETFKDFYGMEEPIEQIVSYLKHAAQGLEERKQVLYLLGPVGGGKSSLA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
EKLKSLMQKLPIYVLSANGERSPVNDHPFCLFDVYEDGELLKNEYGIEPRNLRSIMSPWA
HHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHH
AKRLHEFGGDITKFKVIKVHPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
HHHHHHHCCCEEEEEEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMIL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
AHSNESEWQTFRNNKNNEAFLDRVYIVKVPYCLRVSEEMKIYQKLLEHSELSHAPCSPST
EECCCHHHHHHHCCCCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LDILAQFSILSRLKEPENSSLFSKMRVYDGETLKDTDPKAKSYQEYRDFAGVDEGMSGLS
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
TRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDIADKYTEFLKGFLIPKYV
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRSALNDELEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKTAGISNPKDFRNEIVNFVLRAKANNNGQNPTWTSYEKLRVVIEKKMFSNTEDLLPVIS
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCEEE
FNGKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRVRKSS
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIFDHYQARYEAAKDEEMSLQDFLSLCSNDKSAYANAAERLLLAIGEPEIIDTALDPQL
CHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
SRIFSNRVISRYETFKDFYGMEEPIEQIVSYLKHAAQGLEERKQVLYLLGPVGGGKSSLA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
EKLKSLMQKLPIYVLSANGERSPVNDHPFCLFDVYEDGELLKNEYGIEPRNLRSIMSPWA
HHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHH
AKRLHEFGGDITKFKVIKVHPSILDQIGIAKTEPGDENNQDISSLVGKVDIRQLEHFAQD
HHHHHHHCCCEEEEEEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DPDAYSYSGSLCKANQGLMEFVEMFKAPIKVLHPLLTATQEGNFNGTEGLSALPFDGMIL
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
AHSNESEWQTFRNNKNNEAFLDRVYIVKVPYCLRVSEEMKIYQKLLEHSELSHAPCSPST
EECCCHHHHHHHCCCCCHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LDILAQFSILSRLKEPENSSLFSKMRVYDGETLKDTDPKAKSYQEYRDFAGVDEGMSGLS
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
TRFAFKILSRVFNFDQTEVAANPVHLFYVIEQQIEREQFAQDIADKYTEFLKGFLIPKYV
HHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRSALNDELEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKTAGISNPKDFRNEIVNFVLRAKANNNGQNPTWTSYEKLRVVIEKKMFSNTEDLLPVIS
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCEEE
FNGKTSTDDQKKHDDFVARMMEKGYTKKQVRLLAEWYLRVRKSS
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]