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The map label for this gene is tolA [C]

Identifier: 172087680

GI number: 172087680

Start: 1053858

End: 1054898

Strand: Direct

Name: tolA [C]

Synonym: VF_0960

Alternate gene names: 172087680

Gene position: 1053858-1054898 (Clockwise)

Preceding gene: 59711566

Following gene: 59711569

Centisome position: 36.37

GC content: 41.02

Gene sequence:

>1041_bases
ATGAAAGCGGATAATAATTACACATTTGCCATTGGTGTTTCTGTAGTGCTTCACTTACTGTTAGTGATAGCACTGATATT
TGGTAGCGATTTTTCTTTAGATGACAAAGCTAAGCCAAATACGATTCAAGCGGTTGTGATTGATCCTGGCACGATAGCTA
AGCAAGCAAATCAAATTCGACAAGAACGAGAAAGAGCTGAGCGAGCTGAGCAAGAACGTTTGAAGAAATTAAAACAGCAA
GCGGCACAGTTAGAAAAGAATCGTAAGGCAGAAGAAGAACGTATTCGTCGATTAAAAGAAAAGCAAGTTCAAGAGAAAAA
AGCCGCTCGTCAAGCGGAAGAAGAACGCAAAAAAGCAGTAGCTGAAGCGAAAAAAGAGAAAGAACGTGCAGTAGCTGCAG
AGGCTGAGCGTAAACGAAAAGCAGACGCAGCAGCTAAAGCAGAAGCGGCAAAACAGGCTAAAATTAAAGCGGATAAAGAA
AAAGCAGCGAAAGAGGCTGCTAAGAAAGCGCAATTAGAAAAAGAGCGAGCAGCTAAAGCTGAAGCAGATCGTAAGGCAAA
AGAAAAAGCGGCCAAAGCAGAAGCTGAAAGAAAAGCGAAAGCAGAGGCTGAACGAGTAGCTAAAGCCAAAGCAGCAGAAA
AAGCTCGTAAAGAAAAAGCAGCGAGAGCAGAAGCTGAGCGTAAACAGAAAGAAGCAGCATTAAATGATATCTTTGCAGGT
TTAGAAGATGAGACGGTTCAGAACTCATCAGCTAAACAACAGCATATTGATAATGAAGTTAATCGCCATGCGGCAATTTA
TACTCAAATGATTCAGCAAAACTTGCTGGTTGATGAGACATATGTAGGTAAAAGCTGTCGAGTGAAAATTAAGTTGGCCT
CTTCCGGATTACTTTTATCTGTGACCACTTTAGGTGGTGATGCTCAAGTTTGTCGAGCTGCAAAAACAGCAGTAACAAAA
GTGAATGTGTTTCCTATGCCAAAGGATGCAGATGTTGTTGCTAAGTTAACGAATATAAACCTTACCGTTCAACCAGAATA
A

Upstream 100 bases:

>100_bases
TATGCTGAAATTGTTTTGGTTTTGGATGAATTGAGTCGAGCGGGCGTTAGTAAAGTAGGCTTGCTCACTGATCTCAAGGA
ATAGAAGTGAATAACCATTG

Downstream 100 bases:

>100_bases
GGAAGAGCAAGTGCTTAAACGATGGATATTAACCCTATTTGTGGTTTGTTTAGGTTTTAGTCAGGTTGCAAAAGCCGAGC
TAGAACTGGTTATTACAGAA

Product: membrane anchored protein in TolA-TolQ-TolR complex

Products: NA

Alternate protein names: LA Family Protein; Outer Membrane Integrity Protein lA; Protein lA; Membrane Anchored Protein In lA-TolQ-TolR Complex; LA Protein Membrane Component

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKADNNYTFAIGVSVVLHLLLVIALIFGSDFSLDDKAKPNTIQAVVIDPGTIAKQANQIRQERERAERAEQERLKKLKQQ
AAQLEKNRKAEEERIRRLKEKQVQEKKAARQAEEERKKAVAEAKKEKERAVAAEAERKRKADAAAKAEAAKQAKIKADKE
KAAKEAAKKAQLEKERAAKAEADRKAKEKAAKAEAERKAKAEAERVAKAKAAEKARKEKAARAEAERKQKEAALNDIFAG
LEDETVQNSSAKQQHIDNEVNRHAAIYTQMIQQNLLVDETYVGKSCRVKIKLASSGLLLSVTTLGGDAQVCRAAKTAVTK
VNVFPMPKDADVVAKLTNINLTVQPE

Sequences:

>Translated_346_residues
MKADNNYTFAIGVSVVLHLLLVIALIFGSDFSLDDKAKPNTIQAVVIDPGTIAKQANQIRQERERAERAEQERLKKLKQQ
AAQLEKNRKAEEERIRRLKEKQVQEKKAARQAEEERKKAVAEAKKEKERAVAAEAERKRKADAAAKAEAAKQAKIKADKE
KAAKEAAKKAQLEKERAAKAEADRKAKEKAAKAEAERKAKAEAERVAKAKAAEKARKEKAARAEAERKQKEAALNDIFAG
LEDETVQNSSAKQQHIDNEVNRHAAIYTQMIQQNLLVDETYVGKSCRVKIKLASSGLLLSVTTLGGDAQVCRAAKTAVTK
VNVFPMPKDADVVAKLTNINLTVQPE
>Mature_346_residues
MKADNNYTFAIGVSVVLHLLLVIALIFGSDFSLDDKAKPNTIQAVVIDPGTIAKQANQIRQERERAERAEQERLKKLKQQ
AAQLEKNRKAEEERIRRLKEKQVQEKKAARQAEEERKKAVAEAKKEKERAVAAEAERKRKADAAAKAEAAKQAKIKADKE
KAAKEAAKKAQLEKERAAKAEADRKAKEKAAKAEAERKAKAEAERVAKAKAAEKARKEKAARAEAERKQKEAALNDIFAG
LEDETVQNSSAKQQHIDNEVNRHAAIYTQMIQQNLLVDETYVGKSCRVKIKLASSGLLLSVTTLGGDAQVCRAAKTAVTK
VNVFPMPKDADVVAKLTNINLTVQPE

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. Also Involved In The Translocation Of Bacteriophage DNA. [C]

COG id: COG3064

COG function: function code M; Membrane protein involved in colicin uptake

Gene ontology:

Cell location: Type II Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38243; Mature: 38243

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADNNYTFAIGVSVVLHLLLVIALIFGSDFSLDDKAKPNTIQAVVIDPGTIAKQANQIR
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
QERERAERAEQERLKKLKQQAAQLEKNRKAEEERIRRLKEKQVQEKKAARQAEEERKKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKKEKERAVAAEAERKRKADAAAKAEAAKQAKIKADKEKAAKEAAKKAQLEKERAAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADRKAKEKAAKAEAERKAKAEAERVAKAKAAEKARKEKAARAEAERKQKEAALNDIFAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LEDETVQNSSAKQQHIDNEVNRHAAIYTQMIQQNLLVDETYVGKSCRVKIKLASSGLLLS
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEE
VTTLGGDAQVCRAAKTAVTKVNVFPMPKDADVVAKLTNINLTVQPE
EEECCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MKADNNYTFAIGVSVVLHLLLVIALIFGSDFSLDDKAKPNTIQAVVIDPGTIAKQANQIR
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
QERERAERAEQERLKKLKQQAAQLEKNRKAEEERIRRLKEKQVQEKKAARQAEEERKKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEAKKEKERAVAAEAERKRKADAAAKAEAAKQAKIKADKEKAAKEAAKKAQLEKERAAKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADRKAKEKAAKAEAERKAKAEAERVAKAKAAEKARKEKAARAEAERKQKEAALNDIFAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LEDETVQNSSAKQQHIDNEVNRHAAIYTQMIQQNLLVDETYVGKSCRVKIKLASSGLLLS
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEE
VTTLGGDAQVCRAAKTAVTKVNVFPMPKDADVVAKLTNINLTVQPE
EEECCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA