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The map label for this gene is thyX [H]

Identifier: 58617433

GI number: 58617433

Start: 1121127

End: 1122020

Strand: Reverse

Name: thyX [H]

Synonym: ERGA_CDS_07060

Alternate gene names: 58617433

Gene position: 1122020-1121127 (Counterclockwise)

Preceding gene: 58617434

Following gene: 58617432

Centisome position: 74.81

GC content: 32.55

Gene sequence:

>894_bases
TTGTTAGTATTAAGTATTAGAATTAAAGTATGGCAGACTATGGAATCAGAGATTACAAAACGTATAGTTGTTCCTGAATT
AGAAGATATTCTTTATAAGGAACATAAGGTTTTAGATAAGGGGTTCGTCAGGTTAGTAGATTATATGGGATCTGATGAAT
CTGTAGTACAGGCTGCTAGAATATCCTATGGAAGAGGTACTAAAAGTGTAAGCCAGGATGCTGCGTTGATTAATTATCTT
ATGCGGCATTCACATACTACACCATTTGAAATGTGTGAAATAAAATTTCATATTAAATTACCTATATTTGTTGCAAGACA
GTGGGTACGTCATAGAACTGCAAATGTTAATGAATATTCTGCTAGATATTCTGTTTTAGATCATGAATTTTATATTCCTG
AGCTTGATCATGTGGCAACTCAATCTGAAGATAATGCACAAGGTAGAGGTAATAGCTTGTCTAATGAGGATGCTCAGTAT
GTAACTGATCTATTAAAAAGAGATTCTGATATGGTATATGAAACCTATAATAAGTTTTTAATAAAAGGTGTTTCAAGAGA
AATATCACGTATTAGCCTTACTCTAAATTATTACACTGAATGGTATTGGAAAATAGATCTACATAATTTATTGCATTTTT
TAAGATTGAGGTCTGATGTGCATGCTCAATATGAAATTAGAGTCTATGCTGAGACTATGTTGGAAATTGTAAAAAAGTGG
GTGCCATTAACTTATGCAGCTTTTGTTGAATATTGTTTAGAATCACAAAGTTTTTCTAAGAGTGCATTGAGTGTTGTCAA
GAAGCTAATTGCTGGTGAGGATGTTGCTAGAGAAGATACTGGTATTGGTAAAAGAGAGTGGAGAGAGTTGATGGATGTTT
TAGCAGATAAATAA

Upstream 100 bases:

>100_bases
TAAATCAAGTATAGTAGTTTTTCTGACTATATATTTTGTAAGTGTGTGTAGAACTTTTATAAATTTCATTATATTTTTAA
ACTTGATCTAATGTAGCCAG

Downstream 100 bases:

>100_bases
ATAATTGTAGTATATAAATCAGATATATAAACTTTCATTGTTGTGGGAAATGGTTGAAAGATACTTTATTGCTGGAACAA
GATTATAAGTGAAGGTTGAG

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGFVRLVDYMGSDESVVQAARISYGRGTKSVSQDAALINYL
MRHSHTTPFEMCEIKFHIKLPIFVARQWVRHRTANVNEYSARYSVLDHEFYIPELDHVATQSEDNAQGRGNSLSNEDAQY
VTDLLKRDSDMVYETYNKFLIKGVSREISRISLTLNYYTEWYWKIDLHNLLHFLRLRSDVHAQYEIRVYAETMLEIVKKW
VPLTYAAFVEYCLESQSFSKSALSVVKKLIAGEDVAREDTGIGKREWRELMDVLADK

Sequences:

>Translated_297_residues
MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGFVRLVDYMGSDESVVQAARISYGRGTKSVSQDAALINYL
MRHSHTTPFEMCEIKFHIKLPIFVARQWVRHRTANVNEYSARYSVLDHEFYIPELDHVATQSEDNAQGRGNSLSNEDAQY
VTDLLKRDSDMVYETYNKFLIKGVSREISRISLTLNYYTEWYWKIDLHNLLHFLRLRSDVHAQYEIRVYAETMLEIVKKW
VPLTYAAFVEYCLESQSFSKSALSVVKKLIAGEDVAREDTGIGKREWRELMDVLADK
>Mature_297_residues
MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGFVRLVDYMGSDESVVQAARISYGRGTKSVSQDAALINYL
MRHSHTTPFEMCEIKFHIKLPIFVARQWVRHRTANVNEYSARYSVLDHEFYIPELDHVATQSEDNAQGRGNSLSNEDAQY
VTDLLKRDSDMVYETYNKFLIKGVSREISRISLTLNYYTEWYWKIDLHNLLHFLRLRSDVHAQYEIRVYAETMLEIVKKW
VPLTYAAFVEYCLESQSFSKSALSVVKKLIAGEDVAREDTGIGKREWRELMDVLADK

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 34762; Mature: 34762

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGFVRLVDYMGSDESVVQAAR
CEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ISYGRGTKSVSQDAALINYLMRHSHTTPFEMCEIKFHIKLPIFVARQWVRHRTANVNEYS
HHCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEEEEECHHHHHHHHHHHHCCCCHHHH
ARYSVLDHEFYIPELDHVATQSEDNAQGRGNSLSNEDAQYVTDLLKRDSDMVYETYNKFL
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
IKGVSREISRISLTLNYYTEWYWKIDLHNLLHFLRLRSDVHAQYEIRVYAETMLEIVKKW
HHHHHHHHHHHEEEEEEEEEEEEEEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHH
VPLTYAAFVEYCLESQSFSKSALSVVKKLIAGEDVAREDTGIGKREWRELMDVLADK
HCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVLSIRIKVWQTMESEITKRIVVPELEDILYKEHKVLDKGFVRLVDYMGSDESVVQAAR
CEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ISYGRGTKSVSQDAALINYLMRHSHTTPFEMCEIKFHIKLPIFVARQWVRHRTANVNEYS
HHCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEEEEECHHHHHHHHHHHHCCCCHHHH
ARYSVLDHEFYIPELDHVATQSEDNAQGRGNSLSNEDAQYVTDLLKRDSDMVYETYNKFL
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
IKGVSREISRISLTLNYYTEWYWKIDLHNLLHFLRLRSDVHAQYEIRVYAETMLEIVKKW
HHHHHHHHHHHEEEEEEEEEEEEEEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHH
VPLTYAAFVEYCLESQSFSKSALSVVKKLIAGEDVAREDTGIGKREWRELMDVLADK
HCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA