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The map label for this gene is sdhB [H]

Identifier: 58617434

GI number: 58617434

Start: 1123744

End: 1124538

Strand: Reverse

Name: sdhB [H]

Synonym: ERGA_CDS_07070

Alternate gene names: 58617434

Gene position: 1124538-1123744 (Counterclockwise)

Preceding gene: 58617435

Following gene: 58617433

Centisome position: 74.97

GC content: 32.83

Gene sequence:

>795_bases
TTGTGTAAAAGGTTTGTTATGGTTCAGTTTTTTTTACCTAAGAATTCTAAGATTAATAAAAATGGGGAAGTATATAATGC
TCCTGAAAATGCAAAAAATGTAAAATGTTTTAAGATATATAGATGGTCTCCAGATGATGATAGCAATCCAAGAATTGATA
CATTTTTTATAGATCTTGATCAATGTGGGCAGATGGTTCTTGATGCTCTTATAAAAATTAAAAATGAGATTGATTCTACA
TTAACATTTAGGAGGTCATGTCGGGAAGGTATATGTGGTTCTTGTGCAATGAATATTGATGGTACTAATACTCTGGCATG
TACAAAGGCCATATCAGATATTAAATCGGATGTTGAGATTTATCCTTTACCACATATGAATGTAATTAAGGATTTGGTAC
CTGATTTAAGCAATTTTTACAAACAATATGAGTCCATTACTCCATGGATGCAAGCTGAAGAGCCTAGTCATAATAAGGAA
AGATTGCAGAGTATAGAAGACAGGAGTAAGTTGGATGGAGTATATGATTGTATATTATGTGCATGTTGTAGTACTAGCTG
TCCTAGTTATTGGTGGAATCCAGATAAGTATTTAGGACCAGCTGCATTATTACAAGTATATAGATGGTTAATTGATAGTC
GGGATGAGGCATCAGATAAAAGGTTGGATATGCTTGATGATGCATTTAAATTATATCGCTGCCATACTATTATGAATTGT
ACCAATACTTGTCCTAAGGGTTTAAATCCTGCTAAGGCAATTGCTGATATTAAGCAAATGATGGTAAGAAGATAA

Upstream 100 bases:

>100_bases
TGTAGAAATTAAGTATAAGGATGTTGCTAAGACGACTTTAACAAATGATGTTCAATATTTTCCCCCACAGAAAAGAGTAT
ATTAGTTATCCGTATAGGAA

Downstream 100 bases:

>100_bases
ATTTTATCTTATATATGTGTGCAGAGGTTGAATAGAATCAGTGATCTTATTAATTACATATTTGTATGTTATTAATAAGA
TGTATTTGGGTTATTCATGA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MCKRFVMVQFFLPKNSKINKNGEVYNAPENAKNVKCFKIYRWSPDDDSNPRIDTFFIDLDQCGQMVLDALIKIKNEIDST
LTFRRSCREGICGSCAMNIDGTNTLACTKAISDIKSDVEIYPLPHMNVIKDLVPDLSNFYKQYESITPWMQAEEPSHNKE
RLQSIEDRSKLDGVYDCILCACCSTSCPSYWWNPDKYLGPAALLQVYRWLIDSRDEASDKRLDMLDDAFKLYRCHTIMNC
TNTCPKGLNPAKAIADIKQMMVRR

Sequences:

>Translated_264_residues
MCKRFVMVQFFLPKNSKINKNGEVYNAPENAKNVKCFKIYRWSPDDDSNPRIDTFFIDLDQCGQMVLDALIKIKNEIDST
LTFRRSCREGICGSCAMNIDGTNTLACTKAISDIKSDVEIYPLPHMNVIKDLVPDLSNFYKQYESITPWMQAEEPSHNKE
RLQSIEDRSKLDGVYDCILCACCSTSCPSYWWNPDKYLGPAALLQVYRWLIDSRDEASDKRLDMLDDAFKLYRCHTIMNC
TNTCPKGLNPAKAIADIKQMMVRR
>Mature_264_residues
MCKRFVMVQFFLPKNSKINKNGEVYNAPENAKNVKCFKIYRWSPDDDSNPRIDTFFIDLDQCGQMVLDALIKIKNEIDST
LTFRRSCREGICGSCAMNIDGTNTLACTKAISDIKSDVEIYPLPHMNVIKDLVPDLSNFYKQYESITPWMQAEEPSHNKE
RLQSIEDRSKLDGVYDCILCACCSTSCPSYWWNPDKYLGPAALLQVYRWLIDSRDEASDKRLDMLDDAFKLYRCHTIMNC
TNTCPKGLNPAKAIADIKQMMVRR

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=241, Percent_Identity=66.804979253112, Blast_Score=343, Evalue=1e-94,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=54.2735042735043, Blast_Score=265, Evalue=2e-72,
Organism=Escherichia coli, GI1790596, Length=228, Percent_Identity=30.2631578947368, Blast_Score=127, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17533915, Length=238, Percent_Identity=61.3445378151261, Blast_Score=317, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=65.5172413793103, Blast_Score=323, Evalue=2e-89,
Organism=Drosophila melanogaster, GI17137106, Length=235, Percent_Identity=65.1063829787234, Blast_Score=335, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24643156, Length=233, Percent_Identity=65.2360515021459, Blast_Score=330, Evalue=5e-91,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 30380; Mature: 30380

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKRFVMVQFFLPKNSKINKNGEVYNAPENAKNVKCFKIYRWSPDDDSNPRIDTFFIDLD
CCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEHH
QCGQMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNIDGTNTLACTKAISDIKSDVEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCEE
YPLPHMNVIKDLVPDLSNFYKQYESITPWMQAEEPSHNKERLQSIEDRSKLDGVYDCILC
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ACCSTSCPSYWWNPDKYLGPAALLQVYRWLIDSRDEASDKRLDMLDDAFKLYRCHTIMNC
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TNTCPKGLNPAKAIADIKQMMVRR
HHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCKRFVMVQFFLPKNSKINKNGEVYNAPENAKNVKCFKIYRWSPDDDSNPRIDTFFIDLD
CCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEHH
QCGQMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNIDGTNTLACTKAISDIKSDVEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCEE
YPLPHMNVIKDLVPDLSNFYKQYESITPWMQAEEPSHNKERLQSIEDRSKLDGVYDCILC
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ACCSTSCPSYWWNPDKYLGPAALLQVYRWLIDSRDEASDKRLDMLDDAFKLYRCHTIMNC
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TNTCPKGLNPAKAIADIKQMMVRR
HHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA