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The map label for this gene is thio [H]

Identifier: 58617313

GI number: 58617313

Start: 954741

End: 955805

Strand: Reverse

Name: thio [H]

Synonym: ERGA_CDS_05860

Alternate gene names: 58617313

Gene position: 955805-954741 (Counterclockwise)

Preceding gene: 58617315

Following gene: 58617310

Centisome position: 63.72

GC content: 32.02

Gene sequence:

>1065_bases
ATGAATAAAAAAGCTGCTGTTGTAGGTGCGGGATTATTAGGTAGGCTGTTGGCATTAAGATTATTACAAGATGGTTGGCA
AGTTACCTTATTTGATAAGTTTGGTAAAAATGATAGGAAAAGTTGTGGTGCTATTGCTGCTGGTATGTTAGGGTTGTACT
CAGAGTTAGAAAAAATGGAGGAAGTTGTTTTTGAATTAGGTATTAGGTCATTGAATTTGTGGCCAAACATTATTAAAAGT
TTAGTAGGGAATACTTTTTTTACAATGTCTGGTAGTATTATTGTAGCTCATAGAAATGATATGTCGGAACTTGAAAGGTC
TATGATGTTCATCAAAAGAAAGTTGAAGATTAATCATTTGAAAATTATGGGTGAACAAGAATTGAAATTATTGGAACCTG
AACTTTTATTCCCTTATGGTATATATTTACCATGGGAAGGTCATATTGATACTTCAGGGCTATTTCAGAATATAATGCAC
ACTTTAGCAAAATATGACATTCAGTGGTATGAACATACTTGTGTAAGTAAAATTGTTGATAAGTATGTAATTTTAGAAAA
TGGTACGGAGTATAAGTTTGAATTTATTTTTGATTGTAGAGGGATAGGAGCAAAGGATGATTTACCTGGTTTAAGAGCAG
TGAGAGGTGAAATAATGGTATTATATGCTCCACAGGTAAGTTTTAATAGGCCTATAAGGATGGTACATCCTAAGTATAGT
GTATATATAGTACCTAGACCAGGGTTTCGTTTTGTTGTTGGAGCTACTGAAATAGAAAGTGAAGATATGTCTGAAGTATC
AGTACAATCTGTATTAGAATTATTGTCTTCAGCTTATTCAGTACATAAAGGTTTTGCTGAAGCGAGGATTATAGAAATGT
CAAAAAATTGTAGAGCAGCATTTCTTGATAATTTACCACGAATATATGTTAATGGTAATATAATTAGTATTAATGGTTTG
TATAGGCATGGTTATTTATTAGCTCCTTCTCTGATAGAGGAGGTTATGTTTTTACTGAATGGATCTTCGAAGAATAATCT
ATCAATTGTTAGTGTACTAAACTAA

Upstream 100 bases:

>100_bases
TAATGATTGACTCTACATGCTGTTTATAATTAAATCGAATGTTTTATTACGAAATTATGTAATTTTAAATTTTTATTTAT
TTTTTAATATATGAATTTAT

Downstream 100 bases:

>100_bases
ATGTAATATAATATTACTTGTCAAGTTTTTTTCAGTATTGCAGTTAGTAAAGATAGTAATGCTCAAATGTGGTAAACTAT
ATGAGGTATTGGTACGTTAA

Product: putative thiamine biosynthesis oxidoreductase thiO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNKKAAVVGAGLLGRLLALRLLQDGWQVTLFDKFGKNDRKSCGAIAAGMLGLYSELEKMEEVVFELGIRSLNLWPNIIKS
LVGNTFFTMSGSIIVAHRNDMSELERSMMFIKRKLKINHLKIMGEQELKLLEPELLFPYGIYLPWEGHIDTSGLFQNIMH
TLAKYDIQWYEHTCVSKIVDKYVILENGTEYKFEFIFDCRGIGAKDDLPGLRAVRGEIMVLYAPQVSFNRPIRMVHPKYS
VYIVPRPGFRFVVGATEIESEDMSEVSVQSVLELLSSAYSVHKGFAEARIIEMSKNCRAAFLDNLPRIYVNGNIISINGL
YRHGYLLAPSLIEEVMFLLNGSSKNNLSIVSVLN

Sequences:

>Translated_354_residues
MNKKAAVVGAGLLGRLLALRLLQDGWQVTLFDKFGKNDRKSCGAIAAGMLGLYSELEKMEEVVFELGIRSLNLWPNIIKS
LVGNTFFTMSGSIIVAHRNDMSELERSMMFIKRKLKINHLKIMGEQELKLLEPELLFPYGIYLPWEGHIDTSGLFQNIMH
TLAKYDIQWYEHTCVSKIVDKYVILENGTEYKFEFIFDCRGIGAKDDLPGLRAVRGEIMVLYAPQVSFNRPIRMVHPKYS
VYIVPRPGFRFVVGATEIESEDMSEVSVQSVLELLSSAYSVHKGFAEARIIEMSKNCRAAFLDNLPRIYVNGNIISINGL
YRHGYLLAPSLIEEVMFLLNGSSKNNLSIVSVLN
>Mature_354_residues
MNKKAAVVGAGLLGRLLALRLLQDGWQVTLFDKFGKNDRKSCGAIAAGMLGLYSELEKMEEVVFELGIRSLNLWPNIIKS
LVGNTFFTMSGSIIVAHRNDMSELERSMMFIKRKLKINHLKIMGEQELKLLEPELLFPYGIYLPWEGHIDTSGLFQNIMH
TLAKYDIQWYEHTCVSKIVDKYVILENGTEYKFEFIFDCRGIGAKDDLPGLRAVRGEIMVLYAPQVSFNRPIRMVHPKYS
VYIVPRPGFRFVVGATEIESEDMSEVSVQSVLELLSSAYSVHKGFAEARIIEMSKNCRAAFLDNLPRIYVNGNIISINGL
YRHGYLLAPSLIEEVMFLLNGSSKNNLSIVSVLN

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 40056; Mature: 40056

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKAAVVGAGLLGRLLALRLLQDGWQVTLFDKFGKNDRKSCGAIAAGMLGLYSELEKME
CCCCCEEECHHHHHHHHHHHHHHCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EVVFELGIRSLNLWPNIIKSLVGNTFFTMSGSIIVAHRNDMSELERSMMFIKRKLKINHL
HHHHHHCCCCCCCCHHHHHHHHCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHCEEEE
KIMGEQELKLLEPELLFPYGIYLPWEGHIDTSGLFQNIMHTLAKYDIQWYEHTCVSKIVD
EEECCHHHHHCCCCEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYVILENGTEYKFEFIFDCRGIGAKDDLPGLRAVRGEIMVLYAPQVSFNRPIRMVHPKYS
CEEEEECCCCEEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCEEEECCCEE
VYIVPRPGFRFVVGATEIESEDMSEVSVQSVLELLSSAYSVHKGFAEARIIEMSKNCRAA
EEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCHHH
FLDNLPRIYVNGNIISINGLYRHGYLLAPSLIEEVMFLLNGSSKNNLSIVSVLN
HHCCCCEEEECCEEEEEECEEECCEEECHHHHHHHHHHHCCCCCCCEEEEEEEC
>Mature Secondary Structure
MNKKAAVVGAGLLGRLLALRLLQDGWQVTLFDKFGKNDRKSCGAIAAGMLGLYSELEKME
CCCCCEEECHHHHHHHHHHHHHHCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EVVFELGIRSLNLWPNIIKSLVGNTFFTMSGSIIVAHRNDMSELERSMMFIKRKLKINHL
HHHHHHCCCCCCCCHHHHHHHHCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHCEEEE
KIMGEQELKLLEPELLFPYGIYLPWEGHIDTSGLFQNIMHTLAKYDIQWYEHTCVSKIVD
EEECCHHHHHCCCCEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYVILENGTEYKFEFIFDCRGIGAKDDLPGLRAVRGEIMVLYAPQVSFNRPIRMVHPKYS
CEEEEECCCCEEEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCEEEECCCEE
VYIVPRPGFRFVVGATEIESEDMSEVSVQSVLELLSSAYSVHKGFAEARIIEMSKNCRAA
EEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCHHH
FLDNLPRIYVNGNIISINGLYRHGYLLAPSLIEEVMFLLNGSSKNNLSIVSVLN
HHCCCCEEEECCEEEEEECEEECCEEECHHHHHHHHHHHCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]