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The map label for this gene is ffh [H]

Identifier: 58617285

GI number: 58617285

Start: 911172

End: 912524

Strand: Reverse

Name: ffh [H]

Synonym: ERGA_CDS_05580

Alternate gene names: 58617285

Gene position: 912524-911172 (Counterclockwise)

Preceding gene: 58617286

Following gene: 58617284

Centisome position: 60.84

GC content: 31.04

Gene sequence:

>1353_bases
ATGTTTGAATCTTTAACTAGTAGTTTAACTGCAGTTCTCCAGAAGATGCAGAGTAAACATGTTATCTCTTCTGAGGATTT
TGATTCTGTTATGGAAGAGGTTAAGGTAGCTTTACTTGAGGCTGATGTTGCGTTGTCTGTAGTTAAGAGTTTTATTAATG
ATATAAAAGATAAAATAGTTGGAGAAACTACAATAAAAGGTGTATTACCAACACAGATGGTAATAAAGAAAATACAAGAT
TGTTTAATTGAGATATTAGGGGTTGAAAAACAAGATCTAGATCTTTCTGCAAAACCTTTTGCTGTGATTATGATGGTAGG
TCTTCAAGGTGTTGGTAAAACTACAACTACAGCAAAATTAGCATTAAGGCTTAAAAATAAAAAGAAAGAAGTGTTGATGG
CATCTTTAGATTTATATCGTCCTGCAGCTCAAACTCAATTGGAAATTTTAGGGAAACAGATAGACGTTAAGACATTACCT
ATTATTGAGAAGCAACAACCTATTGATATAGCTAAGAGGGCAATTACAGTTGCTAAGGAAAGTAACTGTAATGTTTTAAT
TTTTGATACAGCTGGAAGATTACACGTAGATGAGATTATGATGGAGGAATTAAAGGCTATTAAAGCTATTACTTCTCCAA
GTGAAGTTATTTTGGTTGCCGATGCTATGATAGGACAAGATGCTGTTAATGTAGTTAAATCGTTTGATAGTAATATTGGT
ATAACAGGTATAATTTTAACTCGTATTGATGGTGATTCAAGAGGTGGTGCTGCTTTATCAATGAAGATGTCTACTGGTAC
TCCTATTAAATTCCTTGCGACTGGAGAAAAATTAAGTGATTTAGATGATTTTTATCCGGATAGAATTGCTAGAAGAATAT
TGAATATGGGTGATGTTGTATCTTTAGTAGAAAAAGCTACTGAAGTTGTAGGTAAAACTGCTATAGATGAAATGCAGAAG
AAAGCTCAGAAAGGTAAGTTTGATTTAAATGATTTAGTTCAGCAGTTAAAAGCTTTAAATAAACTTGGTGGTATTAGTAA
TATTTTGAAGTTTATGCCTAATTTTGGTTCTGATGTTAAACGTCAAGTTGCTGGAATTGCTAATGATAGTAGAATAAAAC
AATATATAGCTATTGTGAATTCTATGACGAAAAAGGAAAGAGCAAACCCAAAGATATTAAATGGTTCACGTAAAACCAGA
ATTGCAAGAGGTTCTGGTGTACCAGTTAATGTAATTAATATGTTAATCAAGCAATTTAATCAAATGAGTAATTTAATGAA
TAAGTTCAGTAAGGTTGACTATAATAAATTTAAAGATGTAAATTTTATGAATTTACTAAAAAACAATGAATAA

Upstream 100 bases:

>100_bases
AAACTCATGGAAAAGTGGTGAACATATCAAATATGAAATCTTTAGGATTTGCTATAATATTACCTATGTTATTTATTATT
ATTATGGTTAGTGTATATTT

Downstream 100 bases:

>100_bases
TGTTGATGTATTTTGGTTACAAATAGGACTAATATTAGATGTAACGAATATTTGTTATTTAAAGATTAGTTAATAGTAAT
TTAGTTATACATATATTTTT

Product: Signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MFESLTSSLTAVLQKMQSKHVISSEDFDSVMEEVKVALLEADVALSVVKSFINDIKDKIVGETTIKGVLPTQMVIKKIQD
CLIEILGVEKQDLDLSAKPFAVIMMVGLQGVGKTTTTAKLALRLKNKKKEVLMASLDLYRPAAQTQLEILGKQIDVKTLP
IIEKQQPIDIAKRAITVAKESNCNVLIFDTAGRLHVDEIMMEELKAIKAITSPSEVILVADAMIGQDAVNVVKSFDSNIG
ITGIILTRIDGDSRGGAALSMKMSTGTPIKFLATGEKLSDLDDFYPDRIARRILNMGDVVSLVEKATEVVGKTAIDEMQK
KAQKGKFDLNDLVQQLKALNKLGGISNILKFMPNFGSDVKRQVAGIANDSRIKQYIAIVNSMTKKERANPKILNGSRKTR
IARGSGVPVNVINMLIKQFNQMSNLMNKFSKVDYNKFKDVNFMNLLKNNE

Sequences:

>Translated_450_residues
MFESLTSSLTAVLQKMQSKHVISSEDFDSVMEEVKVALLEADVALSVVKSFINDIKDKIVGETTIKGVLPTQMVIKKIQD
CLIEILGVEKQDLDLSAKPFAVIMMVGLQGVGKTTTTAKLALRLKNKKKEVLMASLDLYRPAAQTQLEILGKQIDVKTLP
IIEKQQPIDIAKRAITVAKESNCNVLIFDTAGRLHVDEIMMEELKAIKAITSPSEVILVADAMIGQDAVNVVKSFDSNIG
ITGIILTRIDGDSRGGAALSMKMSTGTPIKFLATGEKLSDLDDFYPDRIARRILNMGDVVSLVEKATEVVGKTAIDEMQK
KAQKGKFDLNDLVQQLKALNKLGGISNILKFMPNFGSDVKRQVAGIANDSRIKQYIAIVNSMTKKERANPKILNGSRKTR
IARGSGVPVNVINMLIKQFNQMSNLMNKFSKVDYNKFKDVNFMNLLKNNE
>Mature_450_residues
MFESLTSSLTAVLQKMQSKHVISSEDFDSVMEEVKVALLEADVALSVVKSFINDIKDKIVGETTIKGVLPTQMVIKKIQD
CLIEILGVEKQDLDLSAKPFAVIMMVGLQGVGKTTTTAKLALRLKNKKKEVLMASLDLYRPAAQTQLEILGKQIDVKTLP
IIEKQQPIDIAKRAITVAKESNCNVLIFDTAGRLHVDEIMMEELKAIKAITSPSEVILVADAMIGQDAVNVVKSFDSNIG
ITGIILTRIDGDSRGGAALSMKMSTGTPIKFLATGEKLSDLDDFYPDRIARRILNMGDVVSLVEKATEVVGKTAIDEMQK
KAQKGKFDLNDLVQQLKALNKLGGISNILKFMPNFGSDVKRQVAGIANDSRIKQYIAIVNSMTKKERANPKILNGSRKTR
IARGSGVPVNVINMLIKQFNQMSNLMNKFSKVDYNKFKDVNFMNLLKNNE

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=436, Percent_Identity=28.4403669724771, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI226371618, Length=339, Percent_Identity=30.0884955752212, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI23308697, Length=332, Percent_Identity=28.3132530120482, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI295424842, Length=332, Percent_Identity=28.3132530120482, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=32.1678321678322, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI1788963, Length=428, Percent_Identity=46.2616822429907, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1789874, Length=219, Percent_Identity=39.2694063926941, Blast_Score=145, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=430, Percent_Identity=27.4418604651163, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI193206261, Length=306, Percent_Identity=29.0849673202614, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=417, Percent_Identity=30.9352517985612, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320498, Length=313, Percent_Identity=26.1980830670927, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17647949, Length=440, Percent_Identity=28.4090909090909, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24641198, Length=210, Percent_Identity=30.952380952381, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49548; Mature: 49548

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESLTSSLTAVLQKMQSKHVISSEDFDSVMEEVKVALLEADVALSVVKSFINDIKDKIV
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GETTIKGVLPTQMVIKKIQDCLIEILGVEKQDLDLSAKPFAVIMMVGLQGVGKTTTTAKL
CHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
ALRLKNKKKEVLMASLDLYRPAAQTQLEILGKQIDVKTLPIIEKQQPIDIAKRAITVAKE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHEEC
SNCNVLIFDTAGRLHVDEIMMEELKAIKAITSPSEVILVADAMIGQDAVNVVKSFDSNIG
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCHHHHHHHHHHCCCCC
ITGIILTRIDGDSRGGAALSMKMSTGTPIKFLATGEKLSDLDDFYPDRIARRILNMGDVV
EEEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHH
SLVEKATEVVGKTAIDEMQKKAQKGKFDLNDLVQQLKALNKLGGISNILKFMPNFGSDVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHH
RQVAGIANDSRIKQYIAIVNSMTKKERANPKILNGSRKTRIARGSGVPVNVINMLIKQFN
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHEEECCCCCCHHHHHHHHHHHH
QMSNLMNKFSKVDYNKFKDVNFMNLLKNNE
HHHHHHHHHHHCCHHHHCCCHHHHHHCCCC
>Mature Secondary Structure
MFESLTSSLTAVLQKMQSKHVISSEDFDSVMEEVKVALLEADVALSVVKSFINDIKDKIV
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GETTIKGVLPTQMVIKKIQDCLIEILGVEKQDLDLSAKPFAVIMMVGLQGVGKTTTTAKL
CHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHH
ALRLKNKKKEVLMASLDLYRPAAQTQLEILGKQIDVKTLPIIEKQQPIDIAKRAITVAKE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHEEC
SNCNVLIFDTAGRLHVDEIMMEELKAIKAITSPSEVILVADAMIGQDAVNVVKSFDSNIG
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCHHHHHHHHHHCCCCC
ITGIILTRIDGDSRGGAALSMKMSTGTPIKFLATGEKLSDLDDFYPDRIARRILNMGDVV
EEEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHH
SLVEKATEVVGKTAIDEMQKKAQKGKFDLNDLVQQLKALNKLGGISNILKFMPNFGSDVK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHH
RQVAGIANDSRIKQYIAIVNSMTKKERANPKILNGSRKTRIARGSGVPVNVINMLIKQFN
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHEEECCCCCCHHHHHHHHHHHH
QMSNLMNKFSKVDYNKFKDVNFMNLLKNNE
HHHHHHHHHHHCCHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]