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The map label for this gene is nuoM [H]

Identifier: 58617286

GI number: 58617286

Start: 912509

End: 914095

Strand: Reverse

Name: nuoM [H]

Synonym: ERGA_CDS_05590

Alternate gene names: 58617286

Gene position: 914095-912509 (Counterclockwise)

Preceding gene: 58617293

Following gene: 58617285

Centisome position: 60.94

GC content: 26.97

Gene sequence:

>1587_bases
GTGACTATGGGTAAGTATGTTATTGACTTAGTTATGAGTTTCTTTGACTTATTTTCTATAACATTGAGTGATTTATTATA
TAAGATAGAAAGCAGTTTGTATTTTTATAATACAGTCTTATTTTTTGTATTTTCTTTAATTATTACTCTAATTTTTCTAT
ATATTTCACAAATAAAGAAGCAAGAGATAATTTTATACCTTTTGTATTATTTAAGTAGTGTAATAGCCATTTCTGCTGAA
AGTTTGCTAAAATTTGTTATTTCTTTTGAAATTATGGCATTAAGTGCAGTTATGATAATTGCTACTGGATCTAATGGAAA
AAATATGCATCAGGTTATACATTACTCTTATATTCATTTTTTTGCTGGAGTACTATTGTTAGTTGGTGCATCTGGTAATG
TGGTTGAATTATCTATAGATTATAACAGCTATTGTAAATTATTTTTGTTAATAGGAATATTAATTAATTGTGCATCTTTC
CCTATGTCATCTTGGGTACCTGATGCATATTCTTCAACAGCTAATAATGGAATTATAGTATTATCTGTTTTTACAACTAA
AGTTGCAGCTTTTGCGTTACTATCTTTTTTTCAAGGAGAAGAGATATTATTGTTTTTAGGTATTACAACTGCTATTTATG
GAATAGTTTTTTCTATATTAGAAAACAATATTAAGCGTTTACTTTGTTACAACTTAGTTGGGCAAATGGGATTAGTTATT
ACTGCTGTAGGTTTTTCATATAGTAGTGGAGTATCTGTTCGTAGTATAATTGTATTTCAGATAGTGTTGTCTATGATATA
TCAAACTTTATTGTTTATAGTTGCTATGTCTGTGATAAATAATACTAGAAAATTTAATCTTAATGAAATTGGTGGATTAT
TAAAAAAGATGCCATTAGAGGCTATATGTTCTGCGATTGCTATATTAAATATGGGAGCATTCCCTGGGACAGCAGGTTTT
ATATCTAAGTTTCTTGTAAGTCATAGTATAGATACTACAGATATGACTAACGCAATAGTGAGTAAGTTATTTTTAGTATG
TAGTACTTTGTTGTTTGTTAGTGTTGGTCTAAAATTTTTTTGGTTTGCATTTCTCTCTAAACCGAGAGATGGTTTTATTT
TTAATCAGATGAAGCAAAATATTGGTGCAAGAGTCTCAATGGTTGTACTAGTATTGATTTGTATTCTTTTAGGAATATAT
GGAAGTTATCATCTTTTCTATAATTTAAGTTATGAACAATTACATAGTGTAATATTACAGGGTGGTATAATAATTGGCAG
TGTACTGTTATTTATTTGTTTTTGTTCCTTTTTTAAAGGAAGAATCAATTTTACTATGGAATTAGATTGGTTTTACAGAA
TTTTGTTAGCTCGTTTTATGTTATTTATTGGTGATTTTTTATTGTATGTTTCTGGTATTATTGTTAGCATAGTAAGTGAT
GTGTTGAATTGTAGTACATTATTGTTATGTGAAACTCATGGAAAAGTGGTGAACATATCAAATATGAAATCTTTAGGATT
TGCTATAATATTACCTATGTTATTTATTATTATTATGGTTAGTGTATATTTATGTTTGAATCTTTAA

Upstream 100 bases:

>100_bases
TATGGTATATTTTCCTTTATATAATTTATAATGCTATTTGTTGCTATGTAATAATTAGTATTAGTATGATATATACGGAA
GTAGGTAATAGTACTATAGA

Downstream 100 bases:

>100_bases
CTAGTAGTTTAACTGCAGTTCTCCAGAAGATGCAGAGTAAACATGTTATCTCTTCTGAGGATTTTGATTCTGTTATGGAA
GAGGTTAAGGTAGCTTTACT

Product: putative monovalent cation/H+ antiporter subunit D

Products: H2; oxidized ferredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MTMGKYVIDLVMSFFDLFSITLSDLLYKIESSLYFYNTVLFFVFSLIITLIFLYISQIKKQEIILYLLYYLSSVIAISAE
SLLKFVISFEIMALSAVMIIATGSNGKNMHQVIHYSYIHFFAGVLLLVGASGNVVELSIDYNSYCKLFLLIGILINCASF
PMSSWVPDAYSSTANNGIIVLSVFTTKVAAFALLSFFQGEEILLFLGITTAIYGIVFSILENNIKRLLCYNLVGQMGLVI
TAVGFSYSSGVSVRSIIVFQIVLSMIYQTLLFIVAMSVINNTRKFNLNEIGGLLKKMPLEAICSAIAILNMGAFPGTAGF
ISKFLVSHSIDTTDMTNAIVSKLFLVCSTLLFVSVGLKFFWFAFLSKPRDGFIFNQMKQNIGARVSMVVLVLICILLGIY
GSYHLFYNLSYEQLHSVILQGGIIIGSVLLFICFCSFFKGRINFTMELDWFYRILLARFMLFIGDFLLYVSGIIVSIVSD
VLNCSTLLLCETHGKVVNISNMKSLGFAIILPMLFIIIMVSVYLCLNL

Sequences:

>Translated_528_residues
MTMGKYVIDLVMSFFDLFSITLSDLLYKIESSLYFYNTVLFFVFSLIITLIFLYISQIKKQEIILYLLYYLSSVIAISAE
SLLKFVISFEIMALSAVMIIATGSNGKNMHQVIHYSYIHFFAGVLLLVGASGNVVELSIDYNSYCKLFLLIGILINCASF
PMSSWVPDAYSSTANNGIIVLSVFTTKVAAFALLSFFQGEEILLFLGITTAIYGIVFSILENNIKRLLCYNLVGQMGLVI
TAVGFSYSSGVSVRSIIVFQIVLSMIYQTLLFIVAMSVINNTRKFNLNEIGGLLKKMPLEAICSAIAILNMGAFPGTAGF
ISKFLVSHSIDTTDMTNAIVSKLFLVCSTLLFVSVGLKFFWFAFLSKPRDGFIFNQMKQNIGARVSMVVLVLICILLGIY
GSYHLFYNLSYEQLHSVILQGGIIIGSVLLFICFCSFFKGRINFTMELDWFYRILLARFMLFIGDFLLYVSGIIVSIVSD
VLNCSTLLLCETHGKVVNISNMKSLGFAIILPMLFIIIMVSVYLCLNL
>Mature_527_residues
TMGKYVIDLVMSFFDLFSITLSDLLYKIESSLYFYNTVLFFVFSLIITLIFLYISQIKKQEIILYLLYYLSSVIAISAES
LLKFVISFEIMALSAVMIIATGSNGKNMHQVIHYSYIHFFAGVLLLVGASGNVVELSIDYNSYCKLFLLIGILINCASFP
MSSWVPDAYSSTANNGIIVLSVFTTKVAAFALLSFFQGEEILLFLGITTAIYGIVFSILENNIKRLLCYNLVGQMGLVIT
AVGFSYSSGVSVRSIIVFQIVLSMIYQTLLFIVAMSVINNTRKFNLNEIGGLLKKMPLEAICSAIAILNMGAFPGTAGFI
SKFLVSHSIDTTDMTNAIVSKLFLVCSTLLFVSVGLKFFWFAFLSKPRDGFIFNQMKQNIGARVSMVVLVLICILLGIYG
SYHLFYNLSYEQLHSVILQGGIIIGSVLLFICFCSFFKGRINFTMELDWFYRILLARFMLFIGDFLLYVSGIIVSIVSDV
LNCSTLLLCETHGKVVNISNMKSLGFAIILPMLFIIIMVSVYLCLNL

Specific function: Unknown

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Escherichia coli, GI1788827, Length=359, Percent_Identity=22.5626740947075, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI2367154, Length=379, Percent_Identity=23.4828496042216, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788613, Length=178, Percent_Identity=28.0898876404494, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788831, Length=188, Percent_Identity=28.7234042553192, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 58931; Mature: 58799

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00989 CLAT_ADAPTOR_S

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMGKYVIDLVMSFFDLFSITLSDLLYKIESSLYFYNTVLFFVFSLIITLIFLYISQIKK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIILYLLYYLSSVIAISAESLLKFVISFEIMALSAVMIIATGSNGKNMHQVIHYSYIHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHH
FAGVLLLVGASGNVVELSIDYNSYCKLFLLIGILINCASFPMSSWVPDAYSSTANNGIIV
HHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEE
LSVFTTKVAAFALLSFFQGEEILLFLGITTAIYGIVFSILENNIKRLLCYNLVGQMGLVI
EEHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVGFSYSSGVSVRSIIVFQIVLSMIYQTLLFIVAMSVINNTRKFNLNEIGGLLKKMPLE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHH
AICSAIAILNMGAFPGTAGFISKFLVSHSIDTTDMTNAIVSKLFLVCSTLLFVSVGLKFF
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFAFLSKPRDGFIFNQMKQNIGARVSMVVLVLICILLGIYGSYHLFYNLSYEQLHSVILQ
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHH
GGIIIGSVLLFICFCSFFKGRINFTMELDWFYRILLARFMLFIGDFLLYVSGIIVSIVSD
CHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNCSTLLLCETHGKVVNISNMKSLGFAIILPMLFIIIMVSVYLCLNL
HHCCHHEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMGKYVIDLVMSFFDLFSITLSDLLYKIESSLYFYNTVLFFVFSLIITLIFLYISQIKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIILYLLYYLSSVIAISAESLLKFVISFEIMALSAVMIIATGSNGKNMHQVIHYSYIHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHH
FAGVLLLVGASGNVVELSIDYNSYCKLFLLIGILINCASFPMSSWVPDAYSSTANNGIIV
HHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEE
LSVFTTKVAAFALLSFFQGEEILLFLGITTAIYGIVFSILENNIKRLLCYNLVGQMGLVI
EEHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVGFSYSSGVSVRSIIVFQIVLSMIYQTLLFIVAMSVINNTRKFNLNEIGGLLKKMPLE
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHH
AICSAIAILNMGAFPGTAGFISKFLVSHSIDTTDMTNAIVSKLFLVCSTLLFVSVGLKFF
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFAFLSKPRDGFIFNQMKQNIGARVSMVVLVLICILLGIYGSYHLFYNLSYEQLHSVILQ
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHEEECCHHHHHHHHHH
GGIIIGSVLLFICFCSFFKGRINFTMELDWFYRILLARFMLFIGDFLLYVSGIIVSIVSD
CHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLNCSTLLLCETHGKVVNISNMKSLGFAIILPMLFIIIMVSVYLCLNL
HHCCHHEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton; reduced ferredoxin [C]

Specific reaction: Proton + reduced ferredoxin = H2 + oxidized ferredoxin [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2016588 [H]