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The map label for this gene is era

Identifier: 58617284

GI number: 58617284

Start: 908651

End: 909541

Strand: Reverse

Name: era

Synonym: ERGA_CDS_05570

Alternate gene names: 58617284

Gene position: 909541-908651 (Counterclockwise)

Preceding gene: 58617285

Following gene: 58617283

Centisome position: 60.64

GC content: 30.42

Gene sequence:

>891_bases
ATGAATCATGTAGGTAGAAAATGTTCTATGAGTGCTATAGTTGGGACAACTAATGCAGGTAAGTCAACATTAGTTAATGT
ATTAGTAGGGCAAAAGGTTGCAGCGGTGACTCCAAAAGTGCAAACTACAAGGGTAAGGATGCATGCTGTTTCAAATCATG
AAAATGTACAGTTGATATTTATAGATACACCAGGTATATTTTCACCAAAGACAAAATTGGAAAAGTTTTTAGTTAAGCAT
GCATGGATGTCTCTCAAGGGCATTGAAAATGTAATAGTATTAGTTGATGTAAAAAACTATTTAAATCAGCATCTGAAAAA
GATTATTGATAGGATAAAACATTCTAATCTTAATGCTATTTTGGTTCTTAACAAGATTGATATAGTTCATCAATCGATAG
TTAGTGAAGTGATAGAATATATGTATTCTTTATATAAATTTTCTAAGGCTTTTACTATTTCTGCATTATATGGAATTGGT
ATAGATAAGTTAGTAGATTATTTGTGTGAAACTTCACCTTATGGTCCTTGGTTATATAATGATGATCAGATTAGTGATGC
ACCTTTGAAGTTTTTTATGGCTGAAATTACACGTGAAAAGTTATTTATAACTTTACGTCATGAGTTGCCGTATTCGTTAT
CTGTGGTTACTGAATTGGTTGAAGAAAAGGAAGATAATAGTTTAATTATTAAACAAGTTATATATGTGACTAAGGATAGT
CATAAGACCATCATTCTGGGTAAGAAAGGTGAAATGGTGAAAAAAATTAGTATGGAATCTAAATCTGATCTTGAAAACAT
ACTTCAAGTAAAAGTACATCTTTTTTTATTTGTAAAAGTTCGAGAGTTTTGGCAGAATCATTTAAATGAGTGTGTAGGAT
ATGCTGAGTAA

Upstream 100 bases:

>100_bases
TAGTTTCTGATTGTATTGTGATCTTAATTATGTGTTATAATTTTGATACAGGTCTTCTGATGTATAAGTATGTTTAATTA
GTTAGTACTAGCAGAAAAAT

Downstream 100 bases:

>100_bases
TTTGTTAGTTTTTGATATTGAAACAGTACCAGATGTGAATGTTTGTACTAATCTTTTAGATAATTTTGATGATGTACATG
GTGTGACTGAGAGAAGAGAT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNHVGRKCSMSAIVGTTNAGKSTLVNVLVGQKVAAVTPKVQTTRVRMHAVSNHENVQLIFIDTPGIFSPKTKLEKFLVKH
AWMSLKGIENVIVLVDVKNYLNQHLKKIIDRIKHSNLNAILVLNKIDIVHQSIVSEVIEYMYSLYKFSKAFTISALYGIG
IDKLVDYLCETSPYGPWLYNDDQISDAPLKFFMAEITREKLFITLRHELPYSLSVVTELVEEKEDNSLIIKQVIYVTKDS
HKTIILGKKGEMVKKISMESKSDLENILQVKVHLFLFVKVREFWQNHLNECVGYAE

Sequences:

>Translated_296_residues
MNHVGRKCSMSAIVGTTNAGKSTLVNVLVGQKVAAVTPKVQTTRVRMHAVSNHENVQLIFIDTPGIFSPKTKLEKFLVKH
AWMSLKGIENVIVLVDVKNYLNQHLKKIIDRIKHSNLNAILVLNKIDIVHQSIVSEVIEYMYSLYKFSKAFTISALYGIG
IDKLVDYLCETSPYGPWLYNDDQISDAPLKFFMAEITREKLFITLRHELPYSLSVVTELVEEKEDNSLIIKQVIYVTKDS
HKTIILGKKGEMVKKISMESKSDLENILQVKVHLFLFVKVREFWQNHLNECVGYAE
>Mature_296_residues
MNHVGRKCSMSAIVGTTNAGKSTLVNVLVGQKVAAVTPKVQTTRVRMHAVSNHENVQLIFIDTPGIFSPKTKLEKFLVKH
AWMSLKGIENVIVLVDVKNYLNQHLKKIIDRIKHSNLNAILVLNKIDIVHQSIVSEVIEYMYSLYKFSKAFTISALYGIG
IDKLVDYLCETSPYGPWLYNDDQISDAPLKFFMAEITREKLFITLRHELPYSLSVVTELVEEKEDNSLIIKQVIYVTKDS
HKTIILGKKGEMVKKISMESKSDLENILQVKVHLFLFVKVREFWQNHLNECVGYAE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=29.8136645962733, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1788919, Length=281, Percent_Identity=31.3167259786477, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=26.5060240963855, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_EHRRG (Q5FFN4)

Other databases:

- EMBL:   CR925677
- RefSeq:   YP_196483.1
- HSSP:   Q9X1F8
- ProteinModelPortal:   Q5FFN4
- SMR:   Q5FFN4
- STRING:   Q5FFN4
- GeneID:   3268413
- GenomeReviews:   CR925677_GR
- KEGG:   erg:ERGA_CDS_05570
- eggNOG:   COG1159
- HOGENOM:   HBG561652
- OMA:   ITREQLF
- ProtClustDB:   PRK00089
- BioCyc:   ERUM302409:ERGA_CDS_05570-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 33795; Mature: 33795

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHVGRKCSMSAIVGTTNAGKSTLVNVLVGQKVAAVTPKVQTTRVRMHAVSNHENVQLIF
CCCCCCCCCCHHEEECCCCCHHHHHHHHHCCCHHHCCCCCHHHEEEEEEECCCCCEEEEE
IDTPGIFSPKTKLEKFLVKHAWMSLKGIENVIVLVDVKNYLNQHLKKIIDRIKHSNLNAI
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEE
LVLNKIDIVHQSIVSEVIEYMYSLYKFSKAFTISALYGIGIDKLVDYLCETSPYGPWLYN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
DDQISDAPLKFFMAEITREKLFITLRHELPYSLSVVTELVEEKEDNSLIIKQVIYVTKDS
CCCCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEHHHHEECCC
HKTIILGKKGEMVKKISMESKSDLENILQVKVHLFLFVKVREFWQNHLNECVGYAE
CCEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNHVGRKCSMSAIVGTTNAGKSTLVNVLVGQKVAAVTPKVQTTRVRMHAVSNHENVQLIF
CCCCCCCCCCHHEEECCCCCHHHHHHHHHCCCHHHCCCCCHHHEEEEEEECCCCCEEEEE
IDTPGIFSPKTKLEKFLVKHAWMSLKGIENVIVLVDVKNYLNQHLKKIIDRIKHSNLNAI
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCEE
LVLNKIDIVHQSIVSEVIEYMYSLYKFSKAFTISALYGIGIDKLVDYLCETSPYGPWLYN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCC
DDQISDAPLKFFMAEITREKLFITLRHELPYSLSVVTELVEEKEDNSLIIKQVIYVTKDS
CCCCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEHHHHEECCC
HKTIILGKKGEMVKKISMESKSDLENILQVKVHLFLFVKVREFWQNHLNECVGYAE
CCEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA