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The map label for this gene is nuoN [H]

Identifier: 58617215

GI number: 58617215

Start: 790776

End: 792200

Strand: Reverse

Name: nuoN [H]

Synonym: ERGA_CDS_04880

Alternate gene names: 58617215

Gene position: 792200-790776 (Counterclockwise)

Preceding gene: 58617216

Following gene: 58617214

Centisome position: 52.82

GC content: 26.6

Gene sequence:

>1425_bases
ATGTATTGGAATAATTTTGTTTATATAATACCTGAAATTTTTTTAATCAGTTCATCTTTAATCCTTTTGTTATTGGGAAT
TGTTGTAGATAAAAAAATTATACATATTTCTTCAGTAATTACATTATTAGTTACTATTGGTATTGTAATAAGTAGTATTG
AAGTTGAGCCTAGGTTGATTTTTGATGGACTTTTAAAATCTAATCTATATATTTCTATTTCGAAAATTGTTGTTTTATTT
TCTAGTAGTACTCTTTTGTTAATGCTATTAGCATCTGGTAGAAATTATTGTTATGAATTTTCTATTATGATCTTATTTGC
AGTTTTTGGATTAATTACTTTAATTTCTGCAAATAACCTACTTTCTTTCTATTTGTCATTTGAAATACAAAGTATAACTT
TATATGCATTGACATGCTTTGATAAGAGTGCTGTTAAATCTTCTGAAGCAGGAATCAAGTATTTTGTCTTAAGTGCACTA
TCTTCTTGTATTATGTTGTATGGGATTTCCATGTTATATGGGTATACAGCACAGGTTGGTTTTGATGAATTACATAATTT
CTTTTCTGGAAGTGAGGTTGTATCTTTAGGTGTAATTTTAGGTATTGTACTTATTTTAATTAGCATTTTCTTTAAATTAT
CTGTCGCTCCTTTTCATATGTGGGTTCCTGATGTATATCAAGGAACTTCGACTATTATGACGGCATTTTTTTCTATTGTT
CCAAAAAGTGCATTTATATTTTTATTAATCAGATTACTTAATGAAGTGCTAATTGATCTGTTCAAAAATTGGCAGCAGAT
CATGATTTTTGTATCTATATTATCTATTTGTATTTCAGCATTTTGTGCAATAAGACAAAATAATCTAAAAAGATTATTTT
CATATGCTGCTATTGGTCATATTGGGTATATGTTGATTGCATTAGCTATGAATACCTTTGATGCTAATGTTGCTGTAATA
TTATATTTATTATTGTATATTGTTATGAATATAGGCCTTTTCTCATTTTTGATGCAGTATGAAAATGACGATTATTCTAT
CTCTAGTCTTACAGGATTACATAACAAGTTCCCTATGATAGCATTTTGTATCTCTGTAATTATGTTGTCCATGGCAGGTA
TACCGCCATTAGGTGGATTTTTTGCAAAATATTATGTATTATCAAGCTTGATAGAAAATGGTTTTATAGAAATTGCAGTT
ATTTTTGCATTTATTAGCGTTATTTCTTGTTACTATTACTTAAGAATTATTAAAGTTATGTATTTTGATGAAAGTAATGA
TCATTCTTGTAATTTGATAATGAGTAATGGGTTGCTTTTTATTCTATTGACTGCAGTATTAATTAATCTAGTGTTTTTCT
TATTAGTTGGATATGTGAAGCCAGTTATAGGTTATTTTTTACATTTTAATTTTTTTAATGGATAA

Upstream 100 bases:

>100_bases
TTTGGAATATATCCTTATTATATTTTGTTAAAATCTTTGTCTCCATTTATGGAGCAATTGTCGTTAAGAAACTTATACTT
TAGTAGTATTTGAGATTATT

Downstream 100 bases:

>100_bases
TAATGTGAATATTCGATATATAGTTTGTTGAAGTTTTTTATATTAGTTTTGTGAAAACAGTTTCTATATTTGGTTCGACC
GGAGCTATTGGTCAGATGAT

Product: NADH-ubiquinone oxidoreductase chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MYWNNFVYIIPEIFLISSSLILLLLGIVVDKKIIHISSVITLLVTIGIVISSIEVEPRLIFDGLLKSNLYISISKIVVLF
SSSTLLLMLLASGRNYCYEFSIMILFAVFGLITLISANNLLSFYLSFEIQSITLYALTCFDKSAVKSSEAGIKYFVLSAL
SSCIMLYGISMLYGYTAQVGFDELHNFFSGSEVVSLGVILGIVLILISIFFKLSVAPFHMWVPDVYQGTSTIMTAFFSIV
PKSAFIFLLIRLLNEVLIDLFKNWQQIMIFVSILSICISAFCAIRQNNLKRLFSYAAIGHIGYMLIALAMNTFDANVAVI
LYLLLYIVMNIGLFSFLMQYENDDYSISSLTGLHNKFPMIAFCISVIMLSMAGIPPLGGFFAKYYVLSSLIENGFIEIAV
IFAFISVISCYYYLRIIKVMYFDESNDHSCNLIMSNGLLFILLTAVLINLVFFLLVGYVKPVIGYFLHFNFFNG

Sequences:

>Translated_474_residues
MYWNNFVYIIPEIFLISSSLILLLLGIVVDKKIIHISSVITLLVTIGIVISSIEVEPRLIFDGLLKSNLYISISKIVVLF
SSSTLLLMLLASGRNYCYEFSIMILFAVFGLITLISANNLLSFYLSFEIQSITLYALTCFDKSAVKSSEAGIKYFVLSAL
SSCIMLYGISMLYGYTAQVGFDELHNFFSGSEVVSLGVILGIVLILISIFFKLSVAPFHMWVPDVYQGTSTIMTAFFSIV
PKSAFIFLLIRLLNEVLIDLFKNWQQIMIFVSILSICISAFCAIRQNNLKRLFSYAAIGHIGYMLIALAMNTFDANVAVI
LYLLLYIVMNIGLFSFLMQYENDDYSISSLTGLHNKFPMIAFCISVIMLSMAGIPPLGGFFAKYYVLSSLIENGFIEIAV
IFAFISVISCYYYLRIIKVMYFDESNDHSCNLIMSNGLLFILLTAVLINLVFFLLVGYVKPVIGYFLHFNFFNG
>Mature_474_residues
MYWNNFVYIIPEIFLISSSLILLLLGIVVDKKIIHISSVITLLVTIGIVISSIEVEPRLIFDGLLKSNLYISISKIVVLF
SSSTLLLMLLASGRNYCYEFSIMILFAVFGLITLISANNLLSFYLSFEIQSITLYALTCFDKSAVKSSEAGIKYFVLSAL
SSCIMLYGISMLYGYTAQVGFDELHNFFSGSEVVSLGVILGIVLILISIFFKLSVAPFHMWVPDVYQGTSTIMTAFFSIV
PKSAFIFLLIRLLNEVLIDLFKNWQQIMIFVSILSICISAFCAIRQNNLKRLFSYAAIGHIGYMLIALAMNTFDANVAVI
LYLLLYIVMNIGLFSFLMQYENDDYSISSLTGLHNKFPMIAFCISVIMLSMAGIPPLGGFFAKYYVLSSLIENGFIEIAV
IFAFISVISCYYYLRIIKVMYFDESNDHSCNLIMSNGLLFILLTAVLINLVFFLLVGYVKPVIGYFLHFNFFNG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=297, Percent_Identity=26.9360269360269, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI145693160, Length=361, Percent_Identity=31.5789473684211, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788614, Length=335, Percent_Identity=22.089552238806, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788831, Length=298, Percent_Identity=23.1543624161074, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788613, Length=350, Percent_Identity=23.4285714285714, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53281; Mature: 53281

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWNNFVYIIPEIFLISSSLILLLLGIVVDKKIIHISSVITLLVTIGIVISSIEVEPRLI
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FDGLLKSNLYISISKIVVLFSSSTLLLMLLASGRNYCYEFSIMILFAVFGLITLISANNL
HHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSFYLSFEIQSITLYALTCFDKSAVKSSEAGIKYFVLSALSSCIMLYGISMLYGYTAQVG
HHHHHHEEEEHEEEEEEEHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FDELHNFFSGSEVVSLGVILGIVLILISIFFKLSVAPFHMWVPDVYQGTSTIMTAFFSIV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCHHHHHHHHHHHH
PKSAFIFLLIRLLNEVLIDLFKNWQQIMIFVSILSICISAFCAIRQNNLKRLFSYAAIGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGYMLIALAMNTFDANVAVILYLLLYIVMNIGLFSFLMQYENDDYSISSLTGLHNKFPMI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHH
AFCISVIMLSMAGIPPLGGFFAKYYVLSSLIENGFIEIAVIFAFISVISCYYYLRIIKVM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFDESNDHSCNLIMSNGLLFILLTAVLINLVFFLLVGYVKPVIGYFLHFNFFNG
HCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYWNNFVYIIPEIFLISSSLILLLLGIVVDKKIIHISSVITLLVTIGIVISSIEVEPRLI
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FDGLLKSNLYISISKIVVLFSSSTLLLMLLASGRNYCYEFSIMILFAVFGLITLISANNL
HHHHHHCCCEEEHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSFYLSFEIQSITLYALTCFDKSAVKSSEAGIKYFVLSALSSCIMLYGISMLYGYTAQVG
HHHHHHEEEEHEEEEEEEHHCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FDELHNFFSGSEVVSLGVILGIVLILISIFFKLSVAPFHMWVPDVYQGTSTIMTAFFSIV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCHHHHHHHHHHHH
PKSAFIFLLIRLLNEVLIDLFKNWQQIMIFVSILSICISAFCAIRQNNLKRLFSYAAIGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGYMLIALAMNTFDANVAVILYLLLYIVMNIGLFSFLMQYENDDYSISSLTGLHNKFPMI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHH
AFCISVIMLSMAGIPPLGGFFAKYYVLSSLIENGFIEIAVIFAFISVISCYYYLRIIKVM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFDESNDHSCNLIMSNGLLFILLTAVLINLVFFLLVGYVKPVIGYFLHFNFFNG
HCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA