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The map label for this gene is cmpR [H]

Identifier: 56965472

GI number: 56965472

Start: 3867650

End: 3868549

Strand: Direct

Name: cmpR [H]

Synonym: ABC3710

Alternate gene names: 56965472

Gene position: 3867650-3868549 (Clockwise)

Preceding gene: 56965470

Following gene: 56965473

Centisome position: 89.86

GC content: 46.33

Gene sequence:

>900_bases
ATGAATCTTCACGGACTTCGGTTGTTTTATACGGTGGTGCGCACGGGAAGCATCACCAAAGCAGCACAAGCTTTGCACAT
TAGCCAACCAGCTGTTTCGAGCCAACTAAAAGCGTTTGAAGCGGAATTAAACATACCTTTGCTACAAAAGGACGGCAGGG
GGATTGTGCCTACGCCATTTGGAAAACAGCTTGCTGACAAAGCAGAAACGTTATTCTCGGTTGAAACCCATATTGAAGCA
TTTGCTCAACAATTTCGCGATGTAGGCGCGGGGCACATCCATGTCGCTGCCACATATCTTCCGGCAAACTTTTTATTGCC
ACAATTAGCAGGAGCATTCAAAGCCCAATATCCTACAATCGATTTGCAAATCGAAACGGTCAATTCTCAACAGGCATTTG
AAAAACTGGCCCGTTACAAAGCCGATATAGCGATATATGCTGGCACCATCGACAAATGCGCGAAAGACTTTGTTTGGGAT
GAATGGCTAGAAGATGAGCTTTGGTTTGTCGCTGCTCCCTCCCATCGATTGGCCAATGAACGAGTCTCGTTGGCGGAAGT
AGTAATTGAACCATTTGTCATGCGCGAAGAAGGCAGCTCGACAAGGGCGCAATTATTTACGTTATGCCAGGCCAACCACC
TAAAACCGCCAACGATTGCTTTGCAGTTCAGTGGATTGAACGAAGCCCTTTCTGCTGTGATGGCCGGTTTTGGCATCAAT
TTCGTTTCCTCTTTAGTAGCGAAGGAACATATAAAACGAGGCGATTTAGGGCGCGTCTATGTTGAACATGTCCCCATCGT
CAACAGCATTGCCATTTGTACAAGAAAACAGGAGCAGCAAAACGAACTCGTCCAACGGTTTATTTCCCATTGCAAACAAA
CACGTTTCAAGCACAGCTAG

Upstream 100 bases:

>100_bases
ATTTTGCTTACAATTCCAGTGTATACTCAACATAACAATAAAAATAATCGATCTTTTTTAGGAATCTATAACAATTATTT
ATATATCGGGGAGTGACGGA

Downstream 100 bases:

>100_bases
TGATCTTGTCGATTAAACAAACGTTTAATTAACGCTTTTTTTCATCCTGTCAATAGGGATACACACTTGAAAATTAAGCA
GTATTCCTGTATGCTTAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNLHGLRLFYTVVRTGSITKAAQALHISQPAVSSQLKAFEAELNIPLLQKDGRGIVPTPFGKQLADKAETLFSVETHIEA
FAQQFRDVGAGHIHVAATYLPANFLLPQLAGAFKAQYPTIDLQIETVNSQQAFEKLARYKADIAIYAGTIDKCAKDFVWD
EWLEDELWFVAAPSHRLANERVSLAEVVIEPFVMREEGSSTRAQLFTLCQANHLKPPTIALQFSGLNEALSAVMAGFGIN
FVSSLVAKEHIKRGDLGRVYVEHVPIVNSIAICTRKQEQQNELVQRFISHCKQTRFKHS

Sequences:

>Translated_299_residues
MNLHGLRLFYTVVRTGSITKAAQALHISQPAVSSQLKAFEAELNIPLLQKDGRGIVPTPFGKQLADKAETLFSVETHIEA
FAQQFRDVGAGHIHVAATYLPANFLLPQLAGAFKAQYPTIDLQIETVNSQQAFEKLARYKADIAIYAGTIDKCAKDFVWD
EWLEDELWFVAAPSHRLANERVSLAEVVIEPFVMREEGSSTRAQLFTLCQANHLKPPTIALQFSGLNEALSAVMAGFGIN
FVSSLVAKEHIKRGDLGRVYVEHVPIVNSIAICTRKQEQQNELVQRFISHCKQTRFKHS
>Mature_299_residues
MNLHGLRLFYTVVRTGSITKAAQALHISQPAVSSQLKAFEAELNIPLLQKDGRGIVPTPFGKQLADKAETLFSVETHIEA
FAQQFRDVGAGHIHVAATYLPANFLLPQLAGAFKAQYPTIDLQIETVNSQQAFEKLARYKADIAIYAGTIDKCAKDFVWD
EWLEDELWFVAAPSHRLANERVSLAEVVIEPFVMREEGSSTRAQLFTLCQANHLKPPTIALQFSGLNEALSAVMAGFGIN
FVSSLVAKEHIKRGDLGRVYVEHVPIVNSIAICTRKQEQQNELVQRFISHCKQTRFKHS

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=294, Percent_Identity=29.5918367346939, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI157672245, Length=216, Percent_Identity=30.0925925925926, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790399, Length=262, Percent_Identity=24.8091603053435, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787530, Length=300, Percent_Identity=24, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789204, Length=293, Percent_Identity=25.938566552901, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790208, Length=298, Percent_Identity=22.8187919463087, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=30.8219178082192, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081904, Length=236, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=25.3012048192771, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788296, Length=298, Percent_Identity=22.8187919463087, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=185, Percent_Identity=25.9459459459459, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI145693105, Length=296, Percent_Identity=23.6486486486486, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=149, Percent_Identity=32.2147651006711, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=146, Percent_Identity=30.1369863013699, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33313; Mature: 33313

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHGLRLFYTVVRTGSITKAAQALHISQPAVSSQLKAFEAELNIPLLQKDGRGIVPTPF
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
GKQLADKAETLFSVETHIEAFAQQFRDVGAGHIHVAATYLPANFLLPQLAGAFKAQYPTI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEE
DLQIETVNSQQAFEKLARYKADIAIYAGTIDKCAKDFVWDEWLEDELWFVAAPSHRLANE
EEEEEECCHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
RVSLAEVVIEPFVMREEGSSTRAQLFTLCQANHLKPPTIALQFSGLNEALSAVMAGFGIN
HHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCHH
FVSSLVAKEHIKRGDLGRVYVEHVPIVNSIAICTRKQEQQNELVQRFISHCKQTRFKHS
HHHHHHHHHHHCCCCCCEEHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLHGLRLFYTVVRTGSITKAAQALHISQPAVSSQLKAFEAELNIPLLQKDGRGIVPTPF
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
GKQLADKAETLFSVETHIEAFAQQFRDVGAGHIHVAATYLPANFLLPQLAGAFKAQYPTI
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEE
DLQIETVNSQQAFEKLARYKADIAIYAGTIDKCAKDFVWDEWLEDELWFVAAPSHRLANE
EEEEEECCHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
RVSLAEVVIEPFVMREEGSSTRAQLFTLCQANHLKPPTIALQFSGLNEALSAVMAGFGIN
HHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCHH
FVSSLVAKEHIKRGDLGRVYVEHVPIVNSIAICTRKQEQQNELVQRFISHCKQTRFKHS
HHHHHHHHHHHCCCCCCEEHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]