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The map label for this gene is yrbD [H]

Identifier: 56965470

GI number: 56965470

Start: 3865272

End: 3866729

Strand: Direct

Name: yrbD [H]

Synonym: ABC3708

Alternate gene names: 56965470

Gene position: 3865272-3866729 (Clockwise)

Preceding gene: 56965461

Following gene: 56965472

Centisome position: 89.81

GC content: 47.87

Gene sequence:

>1458_bases
GTGGACGTGGTCTTAGAGTTTATTAATAATGTGCTGTGGAGCTCACCAGTCGTTTACACATTATTAGGTGTAGGATTGAT
TTTTTCATTACTAACAAGATTTTTGCAAGTCCGCCATCTAAAAGATATGTTTACCCTTATGTTCAGTGGCAAAAAATCAG
ATGCCGGCGTTTCCTCTTTCCAAGCGTTATCCGTTGCTTTGGCAGGCCGTGTCGGAACGGGGAACATTGCTGGCGTCGCA
TCAGCGATTTATTTTGGCGGGCCAGGGGCTGTTTTTTGGATGTGGGCCATTGCCTTCCTAGGCGCCTCCAGCGCGTTTAT
TGAGTCGACGCTTGCGCAAATTTATAAAGATAAACAAAACGGCCAATACCGAGGCGGGCCTGCTTACTATATTGAAAAAG
GATTAGGCGTAAAATGGTTTGCGATTCTGTTTGCAGTCGCAGCCCTTGTAGCGATGTCTGTGCTTATGCCTGGCGTCCAG
TCCAATTCGATTGCCGCTGCTGTCAATAATGCCTTTAGCATACCGACTTGGGCAACTGGGTTGTTTCTTGTATTGGTTTT
AGGGCTGATTATTTTTGGCGGGATTAAATGGATCGCGAACACCGCCGCTTTTATCGTGCCATTTATGGCCATTGGCTATA
TGTTGATGGCGGCCATCATTATTTTTATGAACCTATCTGCTGTACCAGAAACGATTGCCTTAATCTTTCGCAGTGCGTTC
GGAATGGACTCTCTCTTTGGCGGCTTGCTTGGCAGCGCTATTTCTTGGGGCGTCATGCGCGGCGTTTACTCCAATGAGGC
TGGCCAAGGCACTGGCGCGCATCCCGCGGCAGCAGCCGAAGTATCACACCCAGCTAAGCAAGGGTTGGTGCAAGCGGCCT
CTGTATACATTGACACTTTGCTTGTTTGTTCAGCAACTGCCTTTATGATCTTATTTACAGGGATGTACAATACACAAGGG
CCTGAAGAAGGTACGCATGTGTTTGAAGCGATTCCTGGCGTTGAGGCTGGGCCTCAATTTACACAGGAAGCCATCAACCA
GGTGTTCCCTGCTTTTGGAACGGGATTTGTCGCGATTGCACTCCTATTTTTCGCTTTTACAACGATTATGGCTTACTACT
ATATTGCCGAAACAAACATTGCCTATTTGATGCGCGGGCGCAATGCGGCCTGGCCAATGGTTGTCATTAAGTTGCTGTTG
CTTGGAGCGACGTATTACGGCGCCAACCGAACAGCTGCAAATGCATGGCTCCTTGGCGACATTGGCCTCGGTTTAATGGT
GTGGATCAACATCATTGCCATCGTCCTGCTCGCCAAGCCAGCAATGATCGCCTTAAAGGATTATGAAGCTCAGAAACAAC
AAGGGCTTGACCCTGTTTTCGATCCTAAAAAGTTGGGCATTCAACATGCGACATTCTGGGAAACGTACGAGAAAGGGCCA
GACAAAAATGCTAGTTAA

Upstream 100 bases:

>100_bases
ATAACTTAGTTGAACCAAGAAAGGAGCCGTACATCAAATAAGAATTCGATAAATTCATGGAATATTTAAATTACATCTCT
TTATTTAAGGAGGACGTACA

Downstream 100 bases:

>100_bases
GTTCGCACGCTTTTAGTCAATCATTTCATGAAACAGCTAGCTTCAAATGCCTTGAAGCTAGCTGTTTTTGAGTGTGTCAC
CATTATTAAAAGGAAAAACG

Product: sodium:alanine symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MDVVLEFINNVLWSSPVVYTLLGVGLIFSLLTRFLQVRHLKDMFTLMFSGKKSDAGVSSFQALSVALAGRVGTGNIAGVA
SAIYFGGPGAVFWMWAIAFLGASSAFIESTLAQIYKDKQNGQYRGGPAYYIEKGLGVKWFAILFAVAALVAMSVLMPGVQ
SNSIAAAVNNAFSIPTWATGLFLVLVLGLIIFGGIKWIANTAAFIVPFMAIGYMLMAAIIIFMNLSAVPETIALIFRSAF
GMDSLFGGLLGSAISWGVMRGVYSNEAGQGTGAHPAAAAEVSHPAKQGLVQAASVYIDTLLVCSATAFMILFTGMYNTQG
PEEGTHVFEAIPGVEAGPQFTQEAINQVFPAFGTGFVAIALLFFAFTTIMAYYYIAETNIAYLMRGRNAAWPMVVIKLLL
LGATYYGANRTAANAWLLGDIGLGLMVWINIIAIVLLAKPAMIALKDYEAQKQQGLDPVFDPKKLGIQHATFWETYEKGP
DKNAS

Sequences:

>Translated_485_residues
MDVVLEFINNVLWSSPVVYTLLGVGLIFSLLTRFLQVRHLKDMFTLMFSGKKSDAGVSSFQALSVALAGRVGTGNIAGVA
SAIYFGGPGAVFWMWAIAFLGASSAFIESTLAQIYKDKQNGQYRGGPAYYIEKGLGVKWFAILFAVAALVAMSVLMPGVQ
SNSIAAAVNNAFSIPTWATGLFLVLVLGLIIFGGIKWIANTAAFIVPFMAIGYMLMAAIIIFMNLSAVPETIALIFRSAF
GMDSLFGGLLGSAISWGVMRGVYSNEAGQGTGAHPAAAAEVSHPAKQGLVQAASVYIDTLLVCSATAFMILFTGMYNTQG
PEEGTHVFEAIPGVEAGPQFTQEAINQVFPAFGTGFVAIALLFFAFTTIMAYYYIAETNIAYLMRGRNAAWPMVVIKLLL
LGATYYGANRTAANAWLLGDIGLGLMVWINIIAIVLLAKPAMIALKDYEAQKQQGLDPVFDPKKLGIQHATFWETYEKGP
DKNAS
>Mature_485_residues
MDVVLEFINNVLWSSPVVYTLLGVGLIFSLLTRFLQVRHLKDMFTLMFSGKKSDAGVSSFQALSVALAGRVGTGNIAGVA
SAIYFGGPGAVFWMWAIAFLGASSAFIESTLAQIYKDKQNGQYRGGPAYYIEKGLGVKWFAILFAVAALVAMSVLMPGVQ
SNSIAAAVNNAFSIPTWATGLFLVLVLGLIIFGGIKWIANTAAFIVPFMAIGYMLMAAIIIFMNLSAVPETIALIFRSAF
GMDSLFGGLLGSAISWGVMRGVYSNEAGQGTGAHPAAAAEVSHPAKQGLVQAASVYIDTLLVCSATAFMILFTGMYNTQG
PEEGTHVFEAIPGVEAGPQFTQEAINQVFPAFGTGFVAIALLFFAFTTIMAYYYIAETNIAYLMRGRNAAWPMVVIKLLL
LGATYYGANRTAANAWLLGDIGLGLMVWINIIAIVLLAKPAMIALKDYEAQKQQGLDPVFDPKKLGIQHATFWETYEKGP
DKNAS

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=473, Percent_Identity=38.9006342494715, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 51926; Mature: 51926

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]