Click here to switch to the map view.

The map label for this gene is gluP [H]

Identifier: 56963491

GI number: 56963491

Start: 1854033

End: 1855604

Strand: Direct

Name: gluP [H]

Synonym: ABC1726

Alternate gene names: 56963491

Gene position: 1854033-1855604 (Clockwise)

Preceding gene: 56963490

Following gene: 56963492

Centisome position: 43.08

GC content: 46.06

Gene sequence:

>1572_bases
TTGGATACGGTTGTACACCGCTATTTTTTCTGGAAGATCGTGGAGCATTATGCACTAAAGAAACAGTTCCGCGTCCTTGC
GCTATACAATACGCAAGTATGGCTAGAAGACGATACCGTGAAACCGCGGCGTGTGATTCGCATTGTGCTCTCTGAAGTCG
ATTGGGCGAATCGCCTGAAACGGGATATCGGCCATGCCAAGCAGCAATTCAACACGATTTATAAACAGCTTGGCGTTTGG
GAAATTCAAGGAGAAAACGTCTATGTGATGAGCTTGCCTCCTGTTGACTCATGGGAAGAAACGATGGAACCTTTTACGAT
CGGTAACCGAAAAGGAAAAATCCGCAACATTGCCTTGCATACAGATACGGATACATACAACGAGATTACTGAACAAACAT
TAGGGAATGACGGACTGCCACCGTTTGAGGCTTTGGATTCTCATGAGGCGATGGAGCAGGAGATTTTGCGGATTCACGAA
AACGTAAAACGCACGAGCGTTGGCCGCCAGACAAAAGAACGGCAAACGTTGTTTTTTGGAAAACCTCGCGTGATCTATGC
GCTGTTAATTTCGATATTGATTATGTTTAGCGTCCTTGAAGCAAATGGAGGAAGCACCAACATTGAGACGTTAATTGACT
TTGGCGCAAAATACAATCCGCTCATTGTAGAAGGGGAATGGTGGCGTCTATTTTCAGCGATGTTTTTGCACATTGGCTTT
TTTCATTTGTTTATGAATGGCATGGCGCTTTACTTTTTAGGCAGTGCAGTGGAGCAACTTTTTGGTTCGATACGGTTTTT
GGTCATTTATTTCATGGCTGGCTTATTTGGATCTGCCGTTAGCTTTGCCTTCACCGACTCTTTGTCAGCAGGGGCGTCAG
GGGCTTTATTTGGTTGTTTTGGCGCTTTGCTTTATTTCGGCATTAAACAGCCTTCTTTGTTTTTTCGCACACTGGGCCGC
AGTGTGATCGTGCTCTTGATCATTAACTTTTTCCTTGGTTTTATTGTTCCTGGAATTGACATTGGCGCCCACGGCGGCGG
CTTAGTCGGTGGTTTTTTGGCAGCTGCAGCTGTACGTATGCCAAAGGAAACAAGAAAAACAAATGTGCTATGGTCATTAT
CTGCATTGGCAGGTTATATCGTCCTGGCAGCTAGTTTGCTGTTTTTTGGCTATCAGTCGGCCGCAGGGACAGTCAACCCA
GATATGGCCGCGCTAGAAGCAAATCGCCTGTTTCAGCAAGGGAATTGGGAGGAAGCACGGCCTCTTGTAGCAGAAGGGCT
TGAACAAGATAGTGAGCATGTAGAGCTGCTGTTTTTGCAAGCCTATTTGGATATGCAAGACGGCAAAGATAAGGCCGCAC
AGGAGAAGCTGGAGTTTGTCACTTCTGAAAATCGCCACTTCCATCAAGCGTGGTTTAATCTGGCCCTTATTTATTGGCAG
CAAGGGGAAATTGAGCAAGCTCAACACGCGGTGGAAGAGGCAATTAAACAAGGGGAGCAAGACGAGCATCCAGATGTAGA
AATCGATCGTTATCGAGAAGTGCAGGAAGAAATTGAACAGCAACAGCACTAG

Upstream 100 bases:

>100_bases
CAAAGAAAAGTTCTGACGTGTTGTCAGGGCTTTTCTTTCGTTTCTTTTTAGGCAAACTTGTTATAATAAAAGAACTGGCA
GTAATAAGGAGGAATTAGGC

Downstream 100 bases:

>100_bases
CACGTATTAGGAAGTCAGTGTGCTGTCAAGCAGCCAGTTGAGTAGTGGAACTGGCTTTTTTTGTTGTTCGCTTTTCCTGA
CGGTGACTCACATATTTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MDTVVHRYFFWKIVEHYALKKQFRVLALYNTQVWLEDDTVKPRRVIRIVLSEVDWANRLKRDIGHAKQQFNTIYKQLGVW
EIQGENVYVMSLPPVDSWEETMEPFTIGNRKGKIRNIALHTDTDTYNEITEQTLGNDGLPPFEALDSHEAMEQEILRIHE
NVKRTSVGRQTKERQTLFFGKPRVIYALLISILIMFSVLEANGGSTNIETLIDFGAKYNPLIVEGEWWRLFSAMFLHIGF
FHLFMNGMALYFLGSAVEQLFGSIRFLVIYFMAGLFGSAVSFAFTDSLSAGASGALFGCFGALLYFGIKQPSLFFRTLGR
SVIVLLIINFFLGFIVPGIDIGAHGGGLVGGFLAAAAVRMPKETRKTNVLWSLSALAGYIVLAASLLFFGYQSAAGTVNP
DMAALEANRLFQQGNWEEARPLVAEGLEQDSEHVELLFLQAYLDMQDGKDKAAQEKLEFVTSENRHFHQAWFNLALIYWQ
QGEIEQAQHAVEEAIKQGEQDEHPDVEIDRYREVQEEIEQQQH

Sequences:

>Translated_523_residues
MDTVVHRYFFWKIVEHYALKKQFRVLALYNTQVWLEDDTVKPRRVIRIVLSEVDWANRLKRDIGHAKQQFNTIYKQLGVW
EIQGENVYVMSLPPVDSWEETMEPFTIGNRKGKIRNIALHTDTDTYNEITEQTLGNDGLPPFEALDSHEAMEQEILRIHE
NVKRTSVGRQTKERQTLFFGKPRVIYALLISILIMFSVLEANGGSTNIETLIDFGAKYNPLIVEGEWWRLFSAMFLHIGF
FHLFMNGMALYFLGSAVEQLFGSIRFLVIYFMAGLFGSAVSFAFTDSLSAGASGALFGCFGALLYFGIKQPSLFFRTLGR
SVIVLLIINFFLGFIVPGIDIGAHGGGLVGGFLAAAAVRMPKETRKTNVLWSLSALAGYIVLAASLLFFGYQSAAGTVNP
DMAALEANRLFQQGNWEEARPLVAEGLEQDSEHVELLFLQAYLDMQDGKDKAAQEKLEFVTSENRHFHQAWFNLALIYWQ
QGEIEQAQHAVEEAIKQGEQDEHPDVEIDRYREVQEEIEQQQH
>Mature_523_residues
MDTVVHRYFFWKIVEHYALKKQFRVLALYNTQVWLEDDTVKPRRVIRIVLSEVDWANRLKRDIGHAKQQFNTIYKQLGVW
EIQGENVYVMSLPPVDSWEETMEPFTIGNRKGKIRNIALHTDTDTYNEITEQTLGNDGLPPFEALDSHEAMEQEILRIHE
NVKRTSVGRQTKERQTLFFGKPRVIYALLISILIMFSVLEANGGSTNIETLIDFGAKYNPLIVEGEWWRLFSAMFLHIGF
FHLFMNGMALYFLGSAVEQLFGSIRFLVIYFMAGLFGSAVSFAFTDSLSAGASGALFGCFGALLYFGIKQPSLFFRTLGR
SVIVLLIINFFLGFIVPGIDIGAHGGGLVGGFLAAAAVRMPKETRKTNVLWSLSALAGYIVLAASLLFFGYQSAAGTVNP
DMAALEANRLFQQGNWEEARPLVAEGLEQDSEHVELLFLQAYLDMQDGKDKAAQEKLEFVTSENRHFHQAWFNLALIYWQ
QGEIEQAQHAVEEAIKQGEQDEHPDVEIDRYREVQEEIEQQQH

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 59476; Mature: 59476

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTVVHRYFFWKIVEHYALKKQFRVLALYNTQVWLEDDTVKPRRVIRIVLSEVDWANRLK
CCHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEECCCCCHHHHHHHHHHHCHHHHHHH
RDIGHAKQQFNTIYKQLGVWEIQGENVYVMSLPPVDSWEETMEPFTIGNRKGKIRNIALH
HHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHCCCCCCCCCCCCEEEEEEE
TDTDTYNEITEQTLGNDGLPPFEALDSHEAMEQEILRIHENVKRTSVGRQTKERQTLFFG
CCCCHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECC
KPRVIYALLISILIMFSVLEANGGSTNIETLIDFGAKYNPLIVEGEWWRLFSAMFLHIGF
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
FHLFMNGMALYFLGSAVEQLFGSIRFLVIYFMAGLFGSAVSFAFTDSLSAGASGALFGCF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
GALLYFGIKQPSLFFRTLGRSVIVLLIINFFLGFIVPGIDIGAHGGGLVGGFLAAAAVRM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
PKETRKTNVLWSLSALAGYIVLAASLLFFGYQSAAGTVNPDMAALEANRLFQQGNWEEAR
CHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHCC
PLVAEGLEQDSEHVELLFLQAYLDMQDGKDKAAQEKLEFVTSENRHFHQAWFNLALIYWQ
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEE
QGEIEQAQHAVEEAIKQGEQDEHPDVEIDRYREVQEEIEQQQH
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTVVHRYFFWKIVEHYALKKQFRVLALYNTQVWLEDDTVKPRRVIRIVLSEVDWANRLK
CCHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEECCCCCHHHHHHHHHHHCHHHHHHH
RDIGHAKQQFNTIYKQLGVWEIQGENVYVMSLPPVDSWEETMEPFTIGNRKGKIRNIALH
HHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCHHHHCCCCCCCCCCCCEEEEEEE
TDTDTYNEITEQTLGNDGLPPFEALDSHEAMEQEILRIHENVKRTSVGRQTKERQTLFFG
CCCCHHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEECC
KPRVIYALLISILIMFSVLEANGGSTNIETLIDFGAKYNPLIVEGEWWRLFSAMFLHIGF
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHH
FHLFMNGMALYFLGSAVEQLFGSIRFLVIYFMAGLFGSAVSFAFTDSLSAGASGALFGCF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
GALLYFGIKQPSLFFRTLGRSVIVLLIINFFLGFIVPGIDIGAHGGGLVGGFLAAAAVRM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
PKETRKTNVLWSLSALAGYIVLAASLLFFGYQSAAGTVNPDMAALEANRLFQQGNWEEAR
CHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHCC
PLVAEGLEQDSEHVELLFLQAYLDMQDGKDKAAQEKLEFVTSENRHFHQAWFNLALIYWQ
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEE
QGEIEQAQHAVEEAIKQGEQDEHPDVEIDRYREVQEEIEQQQH
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]