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The map label for this gene is yngJ [H]

Identifier: 56963271

GI number: 56963271

Start: 1631609

End: 1632781

Strand: Direct

Name: yngJ [H]

Synonym: ABC1506

Alternate gene names: 56963271

Gene position: 1631609-1632781 (Clockwise)

Preceding gene: 56963268

Following gene: 56963272

Centisome position: 37.91

GC content: 48.17

Gene sequence:

>1173_bases
ATGACAGTCAGACTGACAAAAGACCAAGAAATGATTAAAGACATGGTTAGGCAATTTGCCCGCAAGGAAATTGCCCCACT
GGCGCGAGAGCTAGATCGAGATTCGCGTTTTCCAGAGACGATTTTTAAAAAGATGGGGCAGCTTGGCTTGCTCGGTTTGC
CGTTCCCCGAAAAATACGGCGGGTCAGGAGGAGATACGGTCTCTTATGCACTTGCTGTCGAAGAAATCGGCTACGCATGC
GGGGGTACCGGTTTGAGTTATGCTGCAGCGGTATCTCTTGGTGCAAGTCCGATTTTCTACTACGGCACAGAAGAACAAAA
GCAAACCTATTTAGTTCCACTTGCAAAAGGCGAATCCCTTGGTGCATTCGGGTTAACAGAACCAAATGCTGGTTCTGACG
CGGGTGGGACGCAGACAAAAGCTGTCTTTGAAAACGGCGACTATATTCTCAATGGTGAGAAATGTTGGATCACGAATGCG
ATGTACGCGCAAACCGTTATCATTACTGCCGTTACCGGAACGCAATCAAACGGCAAAAAACGGATTTCAGCGTTTATTGT
ACCAACAGATACACCTGGTTTTACGATTACGGCTCCTTACGACAAAATGGGTGTCCGCGCTTCAAACACATGTGAACTTG
TCCTTGAAGATGTCCGTGTCCCTGAAAGCAATTTGCTCGGCGATCCTGGAAAAGGCTTCAGTCAATTCCTTTACACGTTG
GATGGTGGGCGAATTTCAATTGCAGCCCTTGCAGTCGGCATTGCCCAAGCTGCCTTTGACCGGGCGTTAGCCTATGCGAA
AGAACGAAAACAATTTTCGAAGCCGATCGGCTCATTCCAAGCGATTCAATTTAAGCTAGCCGATATGGCGATGGAAATTG
AACTTGCTCGTAATATGGTGCACAAGGCAGCTGCTTTAAAGGATGCAGGAGCACCGTTTGGCAAAGAAGCGGCCTATGCC
AAACTGTTCGCTTCTGAAATGGCAACACGCACATGCAACCAGGCCTTGCAAATTCATGGCGGCTATGGCTATATGCGCGA
ATATGAAGTAGAACGGATGCTCCGTGATGCCAAGCTATTGGAAATTGGCGAAGGCACTTCGGAAATCCAACGCCTTGTCA
TTGCTAGGCATTTAGGGTTAGCAGCTTTACAGCAAAAGGAGGCGAAACGGTGA

Upstream 100 bases:

>100_bases
ACGAAAAAGAGTACGTTACGATTTTGGTAACGCTTTCATTTCTAAAAGTTGGCTTTTTCCTGAACGGTCGCTCAGATTAT
GAAAAGAAGGAGAGCATGCC

Downstream 100 bases:

>100_bases
TCAATACAGTATTAATTGCCAACCGTGGCGAAATTGCCTCGCGCATTATCCGTACATGCAAAAAGCTTGGCGTAAAGACT
ATCGCTGTTTATTCAGAAGC

Product: butyryl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MTVRLTKDQEMIKDMVRQFARKEIAPLARELDRDSRFPETIFKKMGQLGLLGLPFPEKYGGSGGDTVSYALAVEEIGYAC
GGTGLSYAAAVSLGASPIFYYGTEEQKQTYLVPLAKGESLGAFGLTEPNAGSDAGGTQTKAVFENGDYILNGEKCWITNA
MYAQTVIITAVTGTQSNGKKRISAFIVPTDTPGFTITAPYDKMGVRASNTCELVLEDVRVPESNLLGDPGKGFSQFLYTL
DGGRISIAALAVGIAQAAFDRALAYAKERKQFSKPIGSFQAIQFKLADMAMEIELARNMVHKAAALKDAGAPFGKEAAYA
KLFASEMATRTCNQALQIHGGYGYMREYEVERMLRDAKLLEIGEGTSEIQRLVIARHLGLAALQQKEAKR

Sequences:

>Translated_390_residues
MTVRLTKDQEMIKDMVRQFARKEIAPLARELDRDSRFPETIFKKMGQLGLLGLPFPEKYGGSGGDTVSYALAVEEIGYAC
GGTGLSYAAAVSLGASPIFYYGTEEQKQTYLVPLAKGESLGAFGLTEPNAGSDAGGTQTKAVFENGDYILNGEKCWITNA
MYAQTVIITAVTGTQSNGKKRISAFIVPTDTPGFTITAPYDKMGVRASNTCELVLEDVRVPESNLLGDPGKGFSQFLYTL
DGGRISIAALAVGIAQAAFDRALAYAKERKQFSKPIGSFQAIQFKLADMAMEIELARNMVHKAAALKDAGAPFGKEAAYA
KLFASEMATRTCNQALQIHGGYGYMREYEVERMLRDAKLLEIGEGTSEIQRLVIARHLGLAALQQKEAKR
>Mature_389_residues
TVRLTKDQEMIKDMVRQFARKEIAPLARELDRDSRFPETIFKKMGQLGLLGLPFPEKYGGSGGDTVSYALAVEEIGYACG
GTGLSYAAAVSLGASPIFYYGTEEQKQTYLVPLAKGESLGAFGLTEPNAGSDAGGTQTKAVFENGDYILNGEKCWITNAM
YAQTVIITAVTGTQSNGKKRISAFIVPTDTPGFTITAPYDKMGVRASNTCELVLEDVRVPESNLLGDPGKGFSQFLYTLD
GGRISIAALAVGIAQAAFDRALAYAKERKQFSKPIGSFQAIQFKLADMAMEIELARNMVHKAAALKDAGAPFGKEAAYAK
LFASEMATRTCNQALQIHGGYGYMREYEVERMLRDAKLLEIGEGTSEIQRLVIARHLGLAALQQKEAKR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=48.5411140583554, Blast_Score=355, Evalue=5e-98,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=40.6417112299465, Blast_Score=281, Evalue=5e-76,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=40, Blast_Score=279, Evalue=4e-75,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=40.3693931398417, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=40.3693931398417, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=41.2979351032448, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI21361497, Length=367, Percent_Identity=39.7820163487738, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=34.5744680851064, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI76496475, Length=396, Percent_Identity=36.8686868686869, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI4557235, Length=396, Percent_Identity=36.8686868686869, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=35.7333333333333, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=33.7765957446808, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI7669494, Length=352, Percent_Identity=34.375, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI48976061, Length=332, Percent_Identity=31.0240963855422, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI211971008, Length=332, Percent_Identity=31.0240963855422, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI38505218, Length=398, Percent_Identity=27.8894472361809, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI218563752, Length=238, Percent_Identity=27.3109243697479, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=33.6842105263158, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1786223, Length=386, Percent_Identity=31.6062176165803, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI87081702, Length=340, Percent_Identity=25.2941176470588, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082384, Length=269, Percent_Identity=27.5092936802974, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=41.0666666666667, Blast_Score=285, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=41.0526315789474, Blast_Score=280, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17570075, Length=388, Percent_Identity=40.7216494845361, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=40, Blast_Score=271, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17508101, Length=383, Percent_Identity=38.3812010443864, Blast_Score=265, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=38.4408602150538, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=34.2175066312997, Blast_Score=217, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI71990804, Length=308, Percent_Identity=39.6103896103896, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=32.5396825396825, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=36, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17505929, Length=357, Percent_Identity=31.3725490196078, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=30.6068601583113, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=36.5942028985507, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=38.135593220339, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=297, Percent_Identity=33.6700336700337, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=32.3651452282158, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=30, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=178, Percent_Identity=33.1460674157303, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=273, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=273, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=46.3611859838275, Blast_Score=338, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=45.2879581151832, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=41.6445623342175, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24660351, Length=383, Percent_Identity=40.4699738903394, Blast_Score=270, Evalue=9e-73,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=39.7849462365591, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI281363737, Length=384, Percent_Identity=35.9375, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=33.5064935064935, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 42258; Mature: 42127

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRLTKDQEMIKDMVRQFARKEIAPLARELDRDSRFPETIFKKMGQLGLLGLPFPEKYG
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCCCCHHHC
GSGGDTVSYALAVEEIGYACGGTGLSYAAAVSLGASPIFYYGTEEQKQTYLVPLAKGESL
CCCCCHHHHEEEHHHHCHHCCCCCHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCC
GAFGLTEPNAGSDAGGTQTKAVFENGDYILNGEKCWITNAMYAQTVIITAVTGTQSNGKK
CCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCEEEEECHHHHEEEEEEEEECCCCCCCE
RISAFIVPTDTPGFTITAPYDKMGVRASNTCELVLEDVRVPESNLLGDPGKGFSQFLYTL
EEEEEEEECCCCCEEEECCHHHHCCCCCCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHEE
DGGRISIAALAVGIAQAAFDRALAYAKERKQFSKPIGSFQAIQFKLADMAMEIELARNMV
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
HKAAALKDAGAPFGKEAAYAKLFASEMATRTCNQALQIHGGYGYMREYEVERMLRDAKLL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHE
EIGEGTSEIQRLVIARHLGLAALQQKEAKR
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVRLTKDQEMIKDMVRQFARKEIAPLARELDRDSRFPETIFKKMGQLGLLGLPFPEKYG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCCCCHHHC
GSGGDTVSYALAVEEIGYACGGTGLSYAAAVSLGASPIFYYGTEEQKQTYLVPLAKGESL
CCCCCHHHHEEEHHHHCHHCCCCCHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCC
GAFGLTEPNAGSDAGGTQTKAVFENGDYILNGEKCWITNAMYAQTVIITAVTGTQSNGKK
CCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCEEEEECHHHHEEEEEEEEECCCCCCCE
RISAFIVPTDTPGFTITAPYDKMGVRASNTCELVLEDVRVPESNLLGDPGKGFSQFLYTL
EEEEEEEECCCCCEEEECCHHHHCCCCCCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHEE
DGGRISIAALAVGIAQAAFDRALAYAKERKQFSKPIGSFQAIQFKLADMAMEIELARNMV
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
HKAAALKDAGAPFGKEAAYAKLFASEMATRTCNQALQIHGGYGYMREYEVERMLRDAKLL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHE
EIGEGTSEIQRLVIARHLGLAALQQKEAKR
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]