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The map label for this gene is bsaA [H]

Identifier: 56963038

GI number: 56963038

Start: 1387466

End: 1387951

Strand: Direct

Name: bsaA [H]

Synonym: ABC1266

Alternate gene names: 56963038

Gene position: 1387466-1387951 (Clockwise)

Preceding gene: 56963037

Following gene: 56963039

Centisome position: 32.24

GC content: 42.59

Gene sequence:

>486_bases
TTGTCTGTGTACGATTTTTCGGTTAAAACGAGTAACGGCCAAGACGTTTCATTATCAGCTTACAAAGGCAATGTTTTGCT
CATTGTCAATACCGCAACTAAATGCGGCTTTGCTTCACAGTTTGCAGGGCTTGAAAAGCTGTACAATGACTATAAGGAAA
AAGGCTTTTATGTGCTCGGCTTTCCAAGCAACCAATTTTTAAACCAGGAGCCGGTTGCCGATGAAGACATGGAACAGGTG
TGTAAAATCAATTTCGGCGTTACGTTCCCACTGTTTGCAAAAACAGATGTGAAAGGCAAACATGCCAACCCGTTGTTCAA
TTATTTGAAAGCGGCCAAAAAGGGAATGTTGAGCGAAGAGATTAAATGGAACTTCACGAAATTTCTCGTCAACCGAAAAG
GCGAAGTCATTAAGCGTTATGCGCCTGCTACAAAACCGGAAACGATTGAAGCAGATGTCATCGAAGAACTGAAGGCCGAT
GCATAG

Upstream 100 bases:

>100_bases
TCATAGTGGGGACGATTTAGCTGCTGCTCGACCGGTGAAACAAATCGGTTTTAATTGGTGCCAAACCGCAGTATACTTAA
AGTGAAAGGAGCGAACCCGT

Downstream 100 bases:

>100_bases
AAAAGGCTGTGCAGCATAGGACGCTGCACAGTTTTTTTAGGAGGATGGCAATATGGCAAATCGTTTGGAAGATGAGGCTG
TTGAGTTTCTTTCCCTTTTT

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSVYDFSVKTSNGQDVSLSAYKGNVLLIVNTATKCGFASQFAGLEKLYNDYKEKGFYVLGFPSNQFLNQEPVADEDMEQV
CKINFGVTFPLFAKTDVKGKHANPLFNYLKAAKKGMLSEEIKWNFTKFLVNRKGEVIKRYAPATKPETIEADVIEELKAD
A

Sequences:

>Translated_161_residues
MSVYDFSVKTSNGQDVSLSAYKGNVLLIVNTATKCGFASQFAGLEKLYNDYKEKGFYVLGFPSNQFLNQEPVADEDMEQV
CKINFGVTFPLFAKTDVKGKHANPLFNYLKAAKKGMLSEEIKWNFTKFLVNRKGEVIKRYAPATKPETIEADVIEELKAD
A
>Mature_160_residues
SVYDFSVKTSNGQDVSLSAYKGNVLLIVNTATKCGFASQFAGLEKLYNDYKEKGFYVLGFPSNQFLNQEPVADEDMEQVC
KINFGVTFPLFAKTDVKGKHANPLFNYLKAAKKGMLSEEIKWNFTKFLVNRKGEVIKRYAPATKPETIEADVIEELKADA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI192455698, Length=153, Percent_Identity=39.2156862745098, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=38.7096774193548, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=38.7096774193548, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI15618997, Length=151, Percent_Identity=38.4105960264901, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=37.6923076923077, Blast_Score=91, Evalue=5e-19,
Organism=Homo sapiens, GI4557629, Length=178, Percent_Identity=30.3370786516854, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI41406084, Length=178, Percent_Identity=32.0224719101124, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI33186887, Length=178, Percent_Identity=30.3370786516854, Blast_Score=81, Evalue=5e-16,
Organism=Homo sapiens, GI6006001, Length=181, Percent_Identity=27.6243093922652, Blast_Score=77, Evalue=6e-15,
Organism=Homo sapiens, GI32967607, Length=183, Percent_Identity=28.9617486338798, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788003, Length=177, Percent_Identity=39.5480225988701, Blast_Score=137, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17506887, Length=157, Percent_Identity=49.0445859872611, Blast_Score=153, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=44.0251572327044, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=39.7515527950311, Blast_Score=122, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=33.9622641509434, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=182, Percent_Identity=31.8681318681319, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17550320, Length=182, Percent_Identity=30.2197802197802, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=36.8421052631579, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=153, Percent_Identity=47.0588235294118, Blast_Score=160, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6322228, Length=155, Percent_Identity=48.3870967741936, Blast_Score=158, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6322826, Length=155, Percent_Identity=38.7096774193548, Blast_Score=120, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24656772, Length=158, Percent_Identity=48.1012658227848, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24656767, Length=158, Percent_Identity=48.1012658227848, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24656777, Length=158, Percent_Identity=48.1012658227848, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI85726443, Length=155, Percent_Identity=38.7096774193548, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 18056; Mature: 17925

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYDFSVKTSNGQDVSLSAYKGNVLLIVNTATKCGFASQFAGLEKLYNDYKEKGFYVLG
CCEEEEEEECCCCCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEE
FPSNQFLNQEPVADEDMEQVCKINFGVTFPLFAKTDVKGKHANPLFNYLKAAKKGMLSEE
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHH
IKWNFTKFLVNRKGEVIKRYAPATKPETIEADVIEELKADA
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SVYDFSVKTSNGQDVSLSAYKGNVLLIVNTATKCGFASQFAGLEKLYNDYKEKGFYVLG
CEEEEEEECCCCCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEE
FPSNQFLNQEPVADEDMEQVCKINFGVTFPLFAKTDVKGKHANPLFNYLKAAKKGMLSEE
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCHH
IKWNFTKFLVNRKGEVIKRYAPATKPETIEADVIEELKADA
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]