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The map label for this gene is erpA [H]

Identifier: 55981604

GI number: 55981604

Start: 1550036

End: 1550416

Strand: Reverse

Name: erpA [H]

Synonym: TTHA1635

Alternate gene names: 55981604

Gene position: 1550416-1550036 (Counterclockwise)

Preceding gene: 55981611

Following gene: 55981603

Centisome position: 83.82

GC content: 66.93

Gene sequence:

>381_bases
ATGGTGGAAACCCAAGAGGCGGTCATCCGCATCACCCCCCTGGCGGCGGAGAAGGCCAAGGAGATCCTTGCCCGCTACGG
CAAGGAGCACGCGGCCATCCGCGTCTACATCAAGTCCGGCGGCTGCTCGGGCTTCCAGTACGGCATGGCCGTGGACGAAA
GGGAGCTTCCGGGGGACACCTTCGTGGAGATGCACGGGGTGCGCCTGGTGGTGGACCGGATGTCCCTGCCCTACCTCGTG
GGCTCGGAGATTGACTGGGTGGAAAGCCTCATGGGCGGGGGCTTTACCGTCCATAACCCCAATGCGGCCAGCACCTGCGG
CTGCGGCCACTCCTTCCGCACCAAGGACCAGGAGGGGGCCCCCCGCACCTGCGGGCACTGA

Upstream 100 bases:

>100_bases
CCTGCACCGCCCGTAGCTCCATGGGTCCATCCTACCTCTGGAAGCTCCCTCACCTTCTCCTACCCCTTCCGTGCTAGCCT
TAGGGGTAAGGAGGTTCGGC

Downstream 100 bases:

>100_bases
GCGTCCGCTTCGCCACGTGGGAGGCTCGTCGGGGCTTCTATAGGCTTTCGCCGCGGTGGGCCACTCAGGGGGCAAAGGGG
CCTGGCTTCAGGCCCCTTTA

Product: iron-sulfur cluster biosynthesis protein IscA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MVETQEAVIRITPLAAEKAKEILARYGKEHAAIRVYIKSGGCSGFQYGMAVDERELPGDTFVEMHGVRLVVDRMSLPYLV
GSEIDWVESLMGGGFTVHNPNAASTCGCGHSFRTKDQEGAPRTCGH

Sequences:

>Translated_126_residues
MVETQEAVIRITPLAAEKAKEILARYGKEHAAIRVYIKSGGCSGFQYGMAVDERELPGDTFVEMHGVRLVVDRMSLPYLV
GSEIDWVESLMGGGFTVHNPNAASTCGCGHSFRTKDQEGAPRTCGH
>Mature_126_residues
MVETQEAVIRITPLAAEKAKEILARYGKEHAAIRVYIKSGGCSGFQYGMAVDERELPGDTFVEMHGVRLVVDRMSLPYLV
GSEIDWVESLMGGGFTVHNPNAASTCGCGHSFRTKDQEGAPRTCGH

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=33.9622641509434, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI160420328, Length=114, Percent_Identity=37.719298245614, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786351, Length=104, Percent_Identity=51.9230769230769, Blast_Score=111, Evalue=1e-26,
Organism=Escherichia coli, GI1788877, Length=104, Percent_Identity=36.5384615384615, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1787974, Length=104, Percent_Identity=32.6923076923077, Blast_Score=68, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=118, Percent_Identity=36.4406779661017, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=109, Percent_Identity=31.1926605504587, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193209025, Length=109, Percent_Identity=31.1926605504587, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=36.7924528301887, Blast_Score=81, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=32.0754716981132, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13701; Mature: 13701

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVETQEAVIRITPLAAEKAKEILARYGKEHAAIRVYIKSGGCSGFQYGMAVDERELPGDT
CCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEECCCEECCCCCCCCC
FVEMHGVRLVVDRMSLPYLVGSEIDWVESLMGGGFTVHNPNAASTCGCGHSFRTKDQEGA
EEEECCEEEEEECCCCCEEECCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCC
PRTCGH
CCCCCC
>Mature Secondary Structure
MVETQEAVIRITPLAAEKAKEILARYGKEHAAIRVYIKSGGCSGFQYGMAVDERELPGDT
CCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEECCCEECCCCCCCCC
FVEMHGVRLVVDRMSLPYLVGSEIDWVESLMGGGFTVHNPNAASTCGCGHSFRTKDQEGA
EEEECCEEEEEECCCCCEEECCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCC
PRTCGH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA