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The map label for this gene is appB [H]

Identifier: 55981602

GI number: 55981602

Start: 1546902

End: 1547912

Strand: Reverse

Name: appB [H]

Synonym: TTHA1633

Alternate gene names: 55981602

Gene position: 1547912-1546902 (Counterclockwise)

Preceding gene: 55981603

Following gene: 55981601

Centisome position: 83.68

GC content: 66.57

Gene sequence:

>1011_bases
GTGTTCGCCTACACGGTGCGCAGGCTTTTGCAGATGATCCCCCTGCTCTTCGCGGCCAGCGTGGTGATCTACGCCCTCCT
GGCCCTGCAGCCGGGGGACCCTTTGGACGAGCTCAGGCGGCAGAACCCCCGCATGACCGCCGAGCAGTTTGAGGCCTTGA
AGCGGGCCTACGGCCTGGACCAGCCCCTCCACATCCGGTACTTCAAGTGGCTCAACCGGGCCTTGCGCGGCGACCTAGGC
TACAGCCGCACCTACGGGATCCCGGCGGCGGAGTACGTCTTTGTCCAGCGTCTGCCCAAAACCCTGATCCTTTCCGGGCT
CGCCCTGACCCTGGCCCTCGTGGTGGCCATCCCCGTGGGGGTTTTCTCCGCCGTGCGGCAGTACTCCCTGGCCGACTACG
CCATCACCTTTCTCTCCTTCGTGGGCTTTTCCATGCCCGTTTTCTTCCTGGGGATCCTCCTCCTCTACCTCTTCGCCATC
GTCCTGCCGGAGAGCATCCCGGGCTTTCCCCGCTTCCCCACGGGCGGGGTGCCCGGGGTGCTCTGGGAGGACGTGCGCTC
TGGGGCGGTGAGCCTCTGGGAGTTCTTGGGCCAGTGGGCCTGGCACCTCGTCCTCCCCGTCCTCACCCTCTCGGCGTTGC
AGATGGCGGAGTGGACGCGCTTCATGCGGGCCTCTCTCCTCGAGGTCCTCTCCCAGGACTACATCCGCACCGCCCGGGCC
AAGGGGCTCGCCGAGCGGGTGGTGCTCTACAAGCACGCCCTCAGGAACGCCCTGATCCCCATCGTGACCCTGGTGGGCCT
CGCCATTCCCGGGGTCTTGGGCGGGGCCACCATCACCGAAACCATCTTCAGCTATCCCGGGATGGGCCGGGCCATCTTTG
ACGCCCTGGTGGAGAAGGACTACAACGTGGCCATGGCCGCCCTGGCCTTTCTGGCCCTGATGACGGCCCTCTTCAACCTC
CTGGCGGACCTGGCCTACGCGGTGGTGGATCCCCGGATCCGTTACAGCTAG

Upstream 100 bases:

>100_bases
CGAAGTACGCCCTTTCCACCAGGTAACCCGGGTGGTATAGTGAGGCCCGCTGGGCTTTAGCCCAGCGGGCTTTTTGGTGG
AACAAACGGGAGGTACAAGG

Downstream 100 bases:

>100_bases
AGGTGCTTCATGGCGACCGCGACCGCTTCCCCTAAGCCCCGGACCTTCTTCAGCCTCTTCTGGCGCCGCCTCCGGCGGCA
CAAGATGGCCATGGCGAGCC

Product: peptide ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MFAYTVRRLLQMIPLLFAASVVIYALLALQPGDPLDELRRQNPRMTAEQFEALKRAYGLDQPLHIRYFKWLNRALRGDLG
YSRTYGIPAAEYVFVQRLPKTLILSGLALTLALVVAIPVGVFSAVRQYSLADYAITFLSFVGFSMPVFFLGILLLYLFAI
VLPESIPGFPRFPTGGVPGVLWEDVRSGAVSLWEFLGQWAWHLVLPVLTLSALQMAEWTRFMRASLLEVLSQDYIRTARA
KGLAERVVLYKHALRNALIPIVTLVGLAIPGVLGGATITETIFSYPGMGRAIFDALVEKDYNVAMAALAFLALMTALFNL
LADLAYAVVDPRIRYS

Sequences:

>Translated_336_residues
MFAYTVRRLLQMIPLLFAASVVIYALLALQPGDPLDELRRQNPRMTAEQFEALKRAYGLDQPLHIRYFKWLNRALRGDLG
YSRTYGIPAAEYVFVQRLPKTLILSGLALTLALVVAIPVGVFSAVRQYSLADYAITFLSFVGFSMPVFFLGILLLYLFAI
VLPESIPGFPRFPTGGVPGVLWEDVRSGAVSLWEFLGQWAWHLVLPVLTLSALQMAEWTRFMRASLLEVLSQDYIRTARA
KGLAERVVLYKHALRNALIPIVTLVGLAIPGVLGGATITETIFSYPGMGRAIFDALVEKDYNVAMAALAFLALMTALFNL
LADLAYAVVDPRIRYS
>Mature_336_residues
MFAYTVRRLLQMIPLLFAASVVIYALLALQPGDPLDELRRQNPRMTAEQFEALKRAYGLDQPLHIRYFKWLNRALRGDLG
YSRTYGIPAAEYVFVQRLPKTLILSGLALTLALVVAIPVGVFSAVRQYSLADYAITFLSFVGFSMPVFFLGILLLYLFAI
VLPESIPGFPRFPTGGVPGVLWEDVRSGAVSLWEFLGQWAWHLVLPVLTLSALQMAEWTRFMRASLLEVLSQDYIRTARA
KGLAERVVLYKHALRNALIPIVTLVGLAIPGVLGGATITETIFSYPGMGRAIFDALVEKDYNVAMAALAFLALMTALFNL
LADLAYAVVDPRIRYS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=350, Percent_Identity=36.8571428571429, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787053, Length=336, Percent_Identity=36.0119047619048, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=35.8208955223881, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1787497, Length=335, Percent_Identity=31.6417910447761, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1787761, Length=333, Percent_Identity=34.2342342342342, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788504, Length=373, Percent_Identity=27.8820375335121, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=32.2344322344322, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37397; Mature: 37397

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAYTVRRLLQMIPLLFAASVVIYALLALQPGDPLDELRRQNPRMTAEQFEALKRAYGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCC
QPLHIRYFKWLNRALRGDLGYSRTYGIPAAEYVFVQRLPKTLILSGLALTLALVVAIPVG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFSAVRQYSLADYAITFLSFVGFSMPVFFLGILLLYLFAIVLPESIPGFPRFPTGGVPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
LWEDVRSGAVSLWEFLGQWAWHLVLPVLTLSALQMAEWTRFMRASLLEVLSQDYIRTARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLAERVVLYKHALRNALIPIVTLVGLAIPGVLGGATITETIFSYPGMGRAIFDALVEKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCC
YNVAMAALAFLALMTALFNLLADLAYAVVDPRIRYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFAYTVRRLLQMIPLLFAASVVIYALLALQPGDPLDELRRQNPRMTAEQFEALKRAYGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCC
QPLHIRYFKWLNRALRGDLGYSRTYGIPAAEYVFVQRLPKTLILSGLALTLALVVAIPVG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFSAVRQYSLADYAITFLSFVGFSMPVFFLGILLLYLFAIVLPESIPGFPRFPTGGVPGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
LWEDVRSGAVSLWEFLGQWAWHLVLPVLTLSALQMAEWTRFMRASLLEVLSQDYIRTARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGLAERVVLYKHALRNALIPIVTLVGLAIPGVLGGATITETIFSYPGMGRAIFDALVEKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCC
YNVAMAALAFLALMTALFNLLADLAYAVVDPRIRYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]