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The map label for this gene is appC [H]

Identifier: 55981601

GI number: 55981601

Start: 1545705

End: 1546892

Strand: Reverse

Name: appC [H]

Synonym: TTHA1632

Alternate gene names: 55981601

Gene position: 1546892-1545705 (Counterclockwise)

Preceding gene: 55981602

Following gene: 55981595

Centisome position: 83.63

GC content: 67.0

Gene sequence:

>1188_bases
ATGGCGACCGCGACCGCTTCCCCTAAGCCCCGGACCTTCTTCAGCCTCTTCTGGCGCCGCCTCCGGCGGCACAAGATGGC
CATGGCGAGCCTTGTGGTCATCGTCCTCCTCGTCCTCATGGCCCTGTTCGCCCCCTGGATCGCCCCCTACGACCCCACGG
CCCAGCCCACGGGCGAGGACGTGGGGGCCTACTACTTCCTGCCCCCTTCTCCCGAACACCCCTTGGGCACGGACGACCTG
GGGCGGGACGTGCTTTCCCGGATCATCTACGGCTCCAGGATCTCCCTCCTCGTGGGGTTCGCCGTGGCCTTGTCCAGCGT
GATCATCGGGACCCTTATGGGCACCCTGGCGGGCTACTACGCCGGGCGGCCCCTCCGCTTCTACCTGGGCCCCTTGCGGC
GGGAGAAGGAGGGGTTTTATCCCTGGAGCTTCGCGCTTTGGCGGGTCTTCTCCTGGGTGCTCTACTACGGGGTCTTGTAC
CTCGCGGTCTCCGTGGCCTGGACCTTGGCGGCGGAGGGGATCCGGGCGGGAAGCCTATGGGGCTACCTGGGCTTCGGCCT
CGTCCTGGCCCTCGCCCTTTGGGCCGCCTGGTTCGGGCTTAGGGGGGAGATCCGCCTGGACCTGGACGTGGCCATAAGCC
GCCTCATTGACTTTATGCTCACCATCCCCACCCTCCCCCTCCTCTTGGTGCTCTCCGCCCTCCTGCGGGACCCCGAGGTG
GCGGTGGGGCGCTGGGCTCAGGGGGTGTTTGGGGACGCCGCCAGCGTGTTCATCATCATCACCATCCTCGTTTTCTTTGG
CTGGCTGGGGACGGCAAGGCTCGTGCGGGGGAGCATCCTCTCCCTGAGGGAGATGGACTACGCCACCGCCGCCCAGGCCC
TGGGGGCCACGGACTTCCGCATCATGTTCCGCCACCTGGTGCCCAACACCATGGCCCCCCTCATCGTCCAGGCCACCTTG
CAGGTGGGCCAGGCCATCCTGGTGGAGGCGGCCCTCTCCTTCCTCGGGTTTGGCATCCAGCCCCCCGTGGCCACCTGGGG
CAACATGCTCACCAACGCCCAAGAGTACATCTTCATCGCCCCTTGGCTTGCCCTGCCGCCGGGCTTCATGATCTTCATCA
CGGTCCTGGCCTTCAACTACCTCGGGGACGGGCTTAGGGACGCTTTGGACCCGAGGAGCCGCCTCTAA

Upstream 100 bases:

>100_bases
CCTGGCCTTTCTGGCCCTGATGACGGCCCTCTTCAACCTCCTGGCGGACCTGGCCTACGCGGTGGTGGATCCCCGGATCC
GTTACAGCTAGAGGTGCTTC

Downstream 100 bases:

>100_bases
GGCCGTCCCATGCCGGCTTGCGCCGGCATGGGGGTTTAGGGGCTGAGCTTCTCCTCGGGGTAGGCGGCCTCCACGAAGTA
AAGGCCGTGGGCCGGGGCGG

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MATATASPKPRTFFSLFWRRLRRHKMAMASLVVIVLLVLMALFAPWIAPYDPTAQPTGEDVGAYYFLPPSPEHPLGTDDL
GRDVLSRIIYGSRISLLVGFAVALSSVIIGTLMGTLAGYYAGRPLRFYLGPLRREKEGFYPWSFALWRVFSWVLYYGVLY
LAVSVAWTLAAEGIRAGSLWGYLGFGLVLALALWAAWFGLRGEIRLDLDVAISRLIDFMLTIPTLPLLLVLSALLRDPEV
AVGRWAQGVFGDAASVFIIITILVFFGWLGTARLVRGSILSLREMDYATAAQALGATDFRIMFRHLVPNTMAPLIVQATL
QVGQAILVEAALSFLGFGIQPPVATWGNMLTNAQEYIFIAPWLALPPGFMIFITVLAFNYLGDGLRDALDPRSRL

Sequences:

>Translated_395_residues
MATATASPKPRTFFSLFWRRLRRHKMAMASLVVIVLLVLMALFAPWIAPYDPTAQPTGEDVGAYYFLPPSPEHPLGTDDL
GRDVLSRIIYGSRISLLVGFAVALSSVIIGTLMGTLAGYYAGRPLRFYLGPLRREKEGFYPWSFALWRVFSWVLYYGVLY
LAVSVAWTLAAEGIRAGSLWGYLGFGLVLALALWAAWFGLRGEIRLDLDVAISRLIDFMLTIPTLPLLLVLSALLRDPEV
AVGRWAQGVFGDAASVFIIITILVFFGWLGTARLVRGSILSLREMDYATAAQALGATDFRIMFRHLVPNTMAPLIVQATL
QVGQAILVEAALSFLGFGIQPPVATWGNMLTNAQEYIFIAPWLALPPGFMIFITVLAFNYLGDGLRDALDPRSRL
>Mature_394_residues
ATATASPKPRTFFSLFWRRLRRHKMAMASLVVIVLLVLMALFAPWIAPYDPTAQPTGEDVGAYYFLPPSPEHPLGTDDLG
RDVLSRIIYGSRISLLVGFAVALSSVIIGTLMGTLAGYYAGRPLRFYLGPLRREKEGFYPWSFALWRVFSWVLYYGVLYL
AVSVAWTLAAEGIRAGSLWGYLGFGLVLALALWAAWFGLRGEIRLDLDVAISRLIDFMLTIPTLPLLLVLSALLRDPEVA
VGRWAQGVFGDAASVFIIITILVFFGWLGTARLVRGSILSLREMDYATAAQALGATDFRIMFRHLVPNTMAPLIVQATLQ
VGQAILVEAALSFLGFGIQPPVATWGNMLTNAQEYIFIAPWLALPPGFMIFITVLAFNYLGDGLRDALDPRSRL

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=186, Percent_Identity=39.247311827957, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787760, Length=185, Percent_Identity=37.8378378378378, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789964, Length=122, Percent_Identity=50, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789889, Length=194, Percent_Identity=35.5670103092784, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787498, Length=218, Percent_Identity=33.4862385321101, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787549, Length=121, Percent_Identity=42.9752066115703, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788505, Length=194, Percent_Identity=28.3505154639175, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43616; Mature: 43485

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATATASPKPRTFFSLFWRRLRRHKMAMASLVVIVLLVLMALFAPWIAPYDPTAQPTGED
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VGAYYFLPPSPEHPLGTDDLGRDVLSRIIYGSRISLLVGFAVALSSVIIGTLMGTLAGYY
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRPLRFYLGPLRREKEGFYPWSFALWRVFSWVLYYGVLYLAVSVAWTLAAEGIRAGSLW
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
GYLGFGLVLALALWAAWFGLRGEIRLDLDVAISRLIDFMLTIPTLPLLLVLSALLRDPEV
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AVGRWAQGVFGDAASVFIIITILVFFGWLGTARLVRGSILSLREMDYATAAQALGATDFR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IMFRHLVPNTMAPLIVQATLQVGQAILVEAALSFLGFGIQPPVATWGNMLTNAQEYIFIA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEE
PWLALPPGFMIFITVLAFNYLGDGLRDALDPRSRL
CHHHCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCC
>Mature Secondary Structure 
ATATASPKPRTFFSLFWRRLRRHKMAMASLVVIVLLVLMALFAPWIAPYDPTAQPTGED
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VGAYYFLPPSPEHPLGTDDLGRDVLSRIIYGSRISLLVGFAVALSSVIIGTLMGTLAGYY
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGRPLRFYLGPLRREKEGFYPWSFALWRVFSWVLYYGVLYLAVSVAWTLAAEGIRAGSLW
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
GYLGFGLVLALALWAAWFGLRGEIRLDLDVAISRLIDFMLTIPTLPLLLVLSALLRDPEV
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AVGRWAQGVFGDAASVFIIITILVFFGWLGTARLVRGSILSLREMDYATAAQALGATDFR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IMFRHLVPNTMAPLIVQATLQVGQAILVEAALSFLGFGIQPPVATWGNMLTNAQEYIFIA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEE
PWLALPPGFMIFITVLAFNYLGDGLRDALDPRSRL
CHHHCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]