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The map label for this gene is tthHB8IR

Identifier: 55981553

GI number: 55981553

Start: 1507447

End: 1508238

Strand: Direct

Name: tthHB8IR

Synonym: TTHA1584

Alternate gene names: 55981553

Gene position: 1507447-1508238 (Clockwise)

Preceding gene: 55981552

Following gene: 55981555

Centisome position: 81.49

GC content: 51.39

Gene sequence:

>792_bases
ATGGCCCCTACACAAGCCCAGAAAGTGCTGGAAGCTTTTGAGGATTTTCTGAAGTGTTTGGACCTCGAGAGCTACCAAGA
AAAATACCGCCCCATCAAAACAGTAGAGCAAGACCTACCTAGAGAGCTTAACCCACTTCCAGACTTGTACGACCACTATT
GGAAGCCCAACGGGAACACCCTTCACTTTCCAGATTTTGAAACTTTCTTCGACCAGTGGTGGGAGAAGCGCCTCCGGCCC
CTAAACGAGTTTATTCGCAAGTATTTTTGGGGATGTTCCTATGAATTTGTCCGTCTCGGCTTAGAAGCGAGGCTCTACCG
GACCGCTGTTTCCATTTGGACGCAATTTCACTTTTGCTATCGCTGGAACGCCTCTTGTCAACTTCGCTTGACGGCCACCT
GGGAGTTGGACGCCCAGGGGATAGATGCACAAATTCAAGCAGAAGACCGCCTGATAGGCATTCAGATAAAAAAGGAAACC
TATCGCTCGGAAGCCCGGGAGGGAAACCGCTTCCTAAGAAGGCGCGAACATTCCGCCCTCCTGGAAGTTCCCTACACGCT
GCAAAGCCCAGAGGAACTCGAAAGAAAAGCCCAGCGTGCCCGAACCAGAGAAGAAGCCTACCGCTTGTGGGTCAAAATCG
CCCACCATCTAGAACGGCTTCCCAACGGATTCGTCATCTTCCGAGAAAGCTACGTAAAGGACTTGGAAAACTTTTTAAAG
CAAAACGCCACTACATTGTCCGGACTCATACCCTGGGATAAGGTAGCCCGGGAAGCCCTCACCGGCCCGTGA

Upstream 100 bases:

>100_bases
AAAACCCTTTACAGGGACTTTGTTCCTCACTTGACGCTTAGAATGTTGGAGCGGATACCTGCGTTGCTTCCCCGAAAGGG
GAACACCGAGAGGAGGAAAC

Downstream 100 bases:

>100_bases
GGTACACCCGGAGGACGAGCCCCACGCAGAAGAGAAGCCCCAGGGCCACGAAAAGCTCGGGGCGCTTGGGCGGGTCCTTG
AGGCCCCGGTAGAACCACCC

Product: type II restriction enzyme TthHB8I

Products: NA

Alternate protein names: R.TthHB8I; Endonuclease TthHB8I; Type II restriction enzyme TthHB8I

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MAPTQAQKVLEAFEDFLKCLDLESYQEKYRPIKTVEQDLPRELNPLPDLYDHYWKPNGNTLHFPDFETFFDQWWEKRLRP
LNEFIRKYFWGCSYEFVRLGLEARLYRTAVSIWTQFHFCYRWNASCQLRLTATWELDAQGIDAQIQAEDRLIGIQIKKET
YRSEAREGNRFLRRREHSALLEVPYTLQSPEELERKAQRARTREEAYRLWVKIAHHLERLPNGFVIFRESYVKDLENFLK
QNATTLSGLIPWDKVAREALTGP

Sequences:

>Translated_263_residues
MAPTQAQKVLEAFEDFLKCLDLESYQEKYRPIKTVEQDLPRELNPLPDLYDHYWKPNGNTLHFPDFETFFDQWWEKRLRP
LNEFIRKYFWGCSYEFVRLGLEARLYRTAVSIWTQFHFCYRWNASCQLRLTATWELDAQGIDAQIQAEDRLIGIQIKKET
YRSEAREGNRFLRRREHSALLEVPYTLQSPEELERKAQRARTREEAYRLWVKIAHHLERLPNGFVIFRESYVKDLENFLK
QNATTLSGLIPWDKVAREALTGP
>Mature_262_residues
APTQAQKVLEAFEDFLKCLDLESYQEKYRPIKTVEQDLPRELNPLPDLYDHYWKPNGNTLHFPDFETFFDQWWEKRLRPL
NEFIRKYFWGCSYEFVRLGLEARLYRTAVSIWTQFHFCYRWNASCQLRLTATWELDAQGIDAQIQAEDRLIGIQIKKETY
RSEAREGNRFLRRREHSALLEVPYTLQSPEELERKAQRARTREEAYRLWVKIAHHLERLPNGFVIFRESYVKDLENFLKQ
NATTLSGLIPWDKVAREALTGP

Specific function: Recognizes the double-stranded sequence TCGA and cleaves after T-1

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): T2T8_THET8 (P29748)

Other databases:

- EMBL:   M76680
- EMBL:   M74795
- EMBL:   AP008226
- RefSeq:   YP_144850.1
- ProteinModelPortal:   P29748
- STRING:   P29748
- REBASE:   1831
- GeneID:   3170138
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA1584
- NMPDR:   fig|300852.3.peg.1896
- OMA:   LECNSEL
- ProtClustDB:   CLSK2395607
- BioCyc:   TTHE300852:TTHA1584-MONOMER
- InterPro:   IPR019073

Pfam domain/function: PF09573 RE_TaqI

EC number: =3.1.21.4

Molecular weight: Translated: 31584; Mature: 31453

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTQAQKVLEAFEDFLKCLDLESYQEKYRPIKTVEQDLPRELNPLPDLYDHYWKPNGNT
CCCHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHCCHHCCCCHHHHHHHCCCCCCE
LHFPDFETFFDQWWEKRLRPLNEFIRKYFWGCSYEFVRLGLEARLYRTAVSIWTQFHFCY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
RWNASCQLRLTATWELDAQGIDAQIQAEDRLIGIQIKKETYRSEAREGNRFLRRREHSAL
EECCCEEEEEEEEEEECCCCCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LEVPYTLQSPEELERKAQRARTREEAYRLWVKIAHHLERLPNGFVIFRESYVKDLENFLK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
QNATTLSGLIPWDKVAREALTGP
CCCHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure 
APTQAQKVLEAFEDFLKCLDLESYQEKYRPIKTVEQDLPRELNPLPDLYDHYWKPNGNT
CCHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHCCHHCCCCHHHHHHHCCCCCCE
LHFPDFETFFDQWWEKRLRPLNEFIRKYFWGCSYEFVRLGLEARLYRTAVSIWTQFHFCY
EECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
RWNASCQLRLTATWELDAQGIDAQIQAEDRLIGIQIKKETYRSEAREGNRFLRRREHSAL
EECCCEEEEEEEEEEECCCCCCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LEVPYTLQSPEELERKAQRARTREEAYRLWVKIAHHLERLPNGFVIFRESYVKDLENFLK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
QNATTLSGLIPWDKVAREALTGP
CCCHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339363