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The map label for this gene is mtnN [H]

Identifier: 55981519

GI number: 55981519

Start: 1476715

End: 1477377

Strand: Reverse

Name: mtnN [H]

Synonym: TTHA1550

Alternate gene names: 55981519

Gene position: 1477377-1476715 (Counterclockwise)

Preceding gene: 55981520

Following gene: 55981518

Centisome position: 79.87

GC content: 74.36

Gene sequence:

>663_bases
GTGACCGCCTTCTTCGCCGCCGAGCCCGAGGAGGCCTCCGCCCTCCGGGAGGCTTTGGGGGCGGGGGAGGCCTTGGAGGC
CCCCTTCCCCCTCCACCGGGGCGAGGGGGTCTTGGTGGCGGAAACGGGCGTGGGCAAGGTGGCGGCCGCCCTGGCCGTGG
CCCACGTCCTCACCCGCTTCCGCCCCTCGGAGAGCTTCTTCCTGGGGGTGGCGGGGGCCCTGGACCCTTCCCTCCGCGCC
TTGGACCTCCTCCTGGCGGAGAAGGCGGTCCAGTGGGACGTGGACCTCACCCCCTTCGGCCGCAAGCCGGGGGAGACCGC
CTTTGGGGTGGCCTTCTTCCCCTCGGACCCCGCCCTCCTCGCCCGGGCGGAGAAGGCCGCCCTGGCCTTGGGCCTTCCCT
TCCGGCGGGGGGTGGTGGCCACGGGGGACCGCTTTCTGGCCCAAAGGGAGGAGGCGGAAAGGCTTCGCGCCCTCCACGGG
GCGGACGCCGTGGAGATGGAGGGGGCCGCGGCCCTCATGGTGGCCTGGCGCTTCCGCCACCCCATGGTCCTCCTGCGCGT
GGTGACGGACGGGGCCGGGGAGGGGGCGGCCTTGGACTTCCAGGCCTTTTTGCGGGAGGCCGCAAGGCGCCTTGGGCTCC
TCGCCCGGGCCCTGGTAGAGTGA

Upstream 100 bases:

>100_bases
GCAACTACCGGGACCATGACCTTCCTGGCGCCAAGGCCTGGGCGGAGAAGGTGCTAAAGGCGGGGCTTAGGGTCCAGGCC
ACCGTTCCCCTGGAGGCGAG

Downstream 100 bases:

>100_bases
GGAGGGGGTTCCATGGAAATCCGGCTCTTCTCGGGGAGCGCCCACCCCGACTTGGCCCGGCGGGTGGCGGAGGCCCTGGG
GGTGCCCTTGGGCAAGGCCC

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTAFFAAEPEEASALREALGAGEALEAPFPLHRGEGVLVAETGVGKVAAALAVAHVLTRFRPSESFFLGVAGALDPSLRA
LDLLLAEKAVQWDVDLTPFGRKPGETAFGVAFFPSDPALLARAEKAALALGLPFRRGVVATGDRFLAQREEAERLRALHG
ADAVEMEGAAALMVAWRFRHPMVLLRVVTDGAGEGAALDFQAFLREAARRLGLLARALVE

Sequences:

>Translated_220_residues
MTAFFAAEPEEASALREALGAGEALEAPFPLHRGEGVLVAETGVGKVAAALAVAHVLTRFRPSESFFLGVAGALDPSLRA
LDLLLAEKAVQWDVDLTPFGRKPGETAFGVAFFPSDPALLARAEKAALALGLPFRRGVVATGDRFLAQREEAERLRALHG
ADAVEMEGAAALMVAWRFRHPMVLLRVVTDGAGEGAALDFQAFLREAARRLGLLARALVE
>Mature_219_residues
TAFFAAEPEEASALREALGAGEALEAPFPLHRGEGVLVAETGVGKVAAALAVAHVLTRFRPSESFFLGVAGALDPSLRAL
DLLLAEKAVQWDVDLTPFGRKPGETAFGVAFFPSDPALLARAEKAALALGLPFRRGVVATGDRFLAQREEAERLRALHGA
DAVEMEGAAALMVAWRFRHPMVLLRVVTDGAGEGAALDFQAFLREAARRLGLLARALVE

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=228, Percent_Identity=32.0175438596491, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 23338; Mature: 23207

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAFFAAEPEEASALREALGAGEALEAPFPLHRGEGVLVAETGVGKVAAALAVAHVLTRF
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
RPSESFFLGVAGALDPSLRALDLLLAEKAVQWDVDLTPFGRKPGETAFGVAFFPSDPALL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHH
ARAEKAALALGLPFRRGVVATGDRFLAQREEAERLRALHGADAVEMEGAAALMVAWRFRH
HHHHHHHHEECCCHHCCEEECCHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCC
PMVLLRVVTDGAGEGAALDFQAFLREAARRLGLLARALVE
CEEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAFFAAEPEEASALREALGAGEALEAPFPLHRGEGVLVAETGVGKVAAALAVAHVLTRF
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
RPSESFFLGVAGALDPSLRALDLLLAEKAVQWDVDLTPFGRKPGETAFGVAFFPSDPALL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHH
ARAEKAALALGLPFRRGVVATGDRFLAQREEAERLRALHGADAVEMEGAAALMVAWRFRH
HHHHHHHHEECCCHHCCEEECCHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCC
PMVLLRVVTDGAGEGAALDFQAFLREAARRLGLLARALVE
CEEEEEEEECCCCCCCEECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]