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The map label for this gene is luxS

Identifier: 55981520

GI number: 55981520

Start: 1477374

End: 1477841

Strand: Reverse

Name: luxS

Synonym: TTHA1551

Alternate gene names: 55981520

Gene position: 1477841-1477374 (Counterclockwise)

Preceding gene: 55981527

Following gene: 55981519

Centisome position: 79.89

GC content: 68.8

Gene sequence:

>468_bases
ATGGCCGAGGTGGAGAGCTTCAGCCTGGACCACACCAAGGTCAAGGCCCCCTACGTGCGCCTGGCGGGGAGGAAGGCCCT
CGCGGGGGGCGTGGTGGAGAAGTACGACCTGAGGCTTGCCCAGCCCAACCGGGAGGCCCTGCCCACGGGGGCCTTGCACA
CCCTGGAGCACCTCCTCGCGGGGTATTTGCGGGACCACCTCCCGGGGGTCATTGACCTCTCCCCCATGGGCTGCCGCACG
GGGTTTTACCTGGTGGTGGAAGGCCCCGTGGGGGAGGAAAAGGTCCTCGAGGCCTTCGCCCAGGCCTTGAAGGACGTCCT
CGCCCACGAGGGGGAGGTCCCCGGGGCGAGCTTCAGGGAGTGCGGCAACTACCGGGACCATGACCTTCCTGGCGCCAAGG
CCTGGGCGGAGAAGGTGCTAAAGGCGGGGCTTAGGGTCCAGGCCACCGTTCCCCTGGAGGCGAGGTGA

Upstream 100 bases:

>100_bases
ACGCCTCCTGGAACCCAAGGGGCGGAAAAAGTCCGGGGGGCTTTGGAGCCTGGGCCTTTCCCTGCTCCCGTCCTGCCCCC
GGGTGGTGTGTAATGGGGGC

Downstream 100 bases:

>100_bases
CCGCCTTCTTCGCCGCCGAGCCCGAGGAGGCCTCCGCCCTCCGGGAGGCTTTGGGGGCGGGGGAGGCCTTGGAGGCCCCC
TTCCCCCTCCACCGGGGCGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MAEVESFSLDHTKVKAPYVRLAGRKALAGGVVEKYDLRLAQPNREALPTGALHTLEHLLAGYLRDHLPGVIDLSPMGCRT
GFYLVVEGPVGEEKVLEAFAQALKDVLAHEGEVPGASFRECGNYRDHDLPGAKAWAEKVLKAGLRVQATVPLEAR

Sequences:

>Translated_155_residues
MAEVESFSLDHTKVKAPYVRLAGRKALAGGVVEKYDLRLAQPNREALPTGALHTLEHLLAGYLRDHLPGVIDLSPMGCRT
GFYLVVEGPVGEEKVLEAFAQALKDVLAHEGEVPGASFRECGNYRDHDLPGAKAWAEKVLKAGLRVQATVPLEAR
>Mature_154_residues
AEVESFSLDHTKVKAPYVRLAGRKALAGGVVEKYDLRLAQPNREALPTGALHTLEHLLAGYLRDHLPGVIDLSPMGCRTG
FYLVVEGPVGEEKVLEAFAQALKDVLAHEGEVPGASFRECGNYRDHDLPGAKAWAEKVLKAGLRVQATVPLEAR

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family

Homologues:

Organism=Escherichia coli, GI1789043, Length=156, Percent_Identity=39.1025641025641, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LUXS_THET2 (Q72IE6)

Other databases:

- EMBL:   AE017221
- RefSeq:   YP_005155.1
- ProteinModelPortal:   Q72IE6
- SMR:   Q72IE6
- STRING:   Q72IE6
- GeneID:   2774483
- GenomeReviews:   AE017221_GR
- eggNOG:   COG1854
- HOGENOM:   HBG347473
- OMA:   VRIAKTM
- PhylomeDB:   Q72IE6
- ProtClustDB:   PRK02260
- BioCyc:   TTHE262724:TT_C1186-MONOMER
- HAMAP:   MF_00091
- InterPro:   IPR011249
- InterPro:   IPR003815
- Gene3D:   G3DSA:3.30.1360.80
- PIRSF:   PIRSF006160
- PRINTS:   PR01487
- ProDom:   PD013172

Pfam domain/function: PF02664 LuxS; SSF63411 Metalloenz_metal-bd

EC number: =4.4.1.21

Molecular weight: Translated: 16824; Mature: 16692

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVESFSLDHTKVKAPYVRLAGRKALAGGVVEKYDLRLAQPNREALPTGALHTLEHLLA
CCCCCCCCCCCHHHCCCHHHHCCCHHHHCCCHHHHHEEECCCCCCCCCCHHHHHHHHHHH
GYLRDHLPGVIDLSPMGCRTGFYLVVEGPVGEEKVLEAFAQALKDVLAHEGEVPGASFRE
HHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
CGNYRDHDLPGAKAWAEKVLKAGLRVQATVPLEAR
HCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure 
AEVESFSLDHTKVKAPYVRLAGRKALAGGVVEKYDLRLAQPNREALPTGALHTLEHLLA
CCCCCCCCCCHHHCCCHHHHCCCHHHHCCCHHHHHEEECCCCCCCCCCHHHHHHHHHHH
GYLRDHLPGVIDLSPMGCRTGFYLVVEGPVGEEKVLEAFAQALKDVLAHEGEVPGASFRE
HHHHHHCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
CGNYRDHDLPGAKAWAEKVLKAGLRVQATVPLEAR
HCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA