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The map label for this gene is sipT [H]

Identifier: 55981337

GI number: 55981337

Start: 1305375

End: 1306181

Strand: Reverse

Name: sipT [H]

Synonym: TTHA1368

Alternate gene names: 55981337

Gene position: 1306181-1305375 (Counterclockwise)

Preceding gene: 55981338

Following gene: 55981333

Centisome position: 70.61

GC content: 67.41

Gene sequence:

>807_bases
ATGAAGGCCTTTTGGGACTACTTGTTCAAGGAGTGGTTCCGCCAGGTGGGGGAGGCCCTCCTGGTGGCCTTTTTGGTCAC
CACCTTCGTCTTCACCACGGTGGGGGTGGTGGGGCAGAGCATGTACCCCACCTTGAGGAACGGCGAGCGGGTCCTGGTGC
CCAAGTGGGAGACCTGGCTCGTCCGCCTGGGGTTCATGGAGTGGCGGCGGGGGGAGATCGCCATCCTCAAGCCCCCGGAG
GGCACCCCCTTCTCCACGGCCCGCTTCCCCGTTTTGGGCTTCTCCTTCCGGGCCTTCTTCATCAAGCGCATCGTGGCCGT
CCCCGGGGACGAGGTCTACGTGGACCGGGGGGTGGTTTACGTGAACGGGAAGCCCTTGGCGGAGACCCACATCACGGACC
GGATCACCCCCTGGCCCGACTCCTTCCCCGGGGTGTGCTACGAGGGGGGGCGCCTCACCCGGATCGTCACCCAGCAAGGG
GATTTCCCGGTGGAGCTTCTTCCCGCCTACCTCCGGCCCCTCAAGGAGATGCTCCTCCCCCCCTCGCAGGAGACTTTGGC
CCGAAGCGAGCTTGGGGAGGTCTGCGAGGTGGGGCGGATCAAGCTGAAGCCGGGGTACTACTTCGTCATGGGGGACAACC
GCACCCTAGGGGGCTCGGAGGACTCCCGCACCTTCGGCCCGATCCCCGTGGAGAGGATCGCGGGGCGGGCGAGCTTCGTC
TGGTGGCCCGTGGTGGTGCGGGAGGAGGGGGGCTTTAGGCTCAACCTCCGCGCCCTCGCCATCCCCCCCGCCTACCGCCT
GGAGTGA

Upstream 100 bases:

>100_bases
TCGGGGAGGTTGCGGTGCAGGACTTCCTCCGCCTCGAGGAGGCGGTGGAGGCGGGCAGGAAGGCGGCCAAGCGCTTTCTG
GAGAGTAGAGTGGGGGAGGT

Downstream 100 bases:

>100_bases
GCTCACTCCAGGACGACCACCACGAGCCTCCCGGGCCCGTGCACCCCTTTGACCATTACCTGGCCGATGTCGGCGCTCTT
GGAGGGGCCGGAGTGGAGGC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKAFWDYLFKEWFRQVGEALLVAFLVTTFVFTTVGVVGQSMYPTLRNGERVLVPKWETWLVRLGFMEWRRGEIAILKPPE
GTPFSTARFPVLGFSFRAFFIKRIVAVPGDEVYVDRGVVYVNGKPLAETHITDRITPWPDSFPGVCYEGGRLTRIVTQQG
DFPVELLPAYLRPLKEMLLPPSQETLARSELGEVCEVGRIKLKPGYYFVMGDNRTLGGSEDSRTFGPIPVERIAGRASFV
WWPVVVREEGGFRLNLRALAIPPAYRLE

Sequences:

>Translated_268_residues
MKAFWDYLFKEWFRQVGEALLVAFLVTTFVFTTVGVVGQSMYPTLRNGERVLVPKWETWLVRLGFMEWRRGEIAILKPPE
GTPFSTARFPVLGFSFRAFFIKRIVAVPGDEVYVDRGVVYVNGKPLAETHITDRITPWPDSFPGVCYEGGRLTRIVTQQG
DFPVELLPAYLRPLKEMLLPPSQETLARSELGEVCEVGRIKLKPGYYFVMGDNRTLGGSEDSRTFGPIPVERIAGRASFV
WWPVVVREEGGFRLNLRALAIPPAYRLE
>Mature_268_residues
MKAFWDYLFKEWFRQVGEALLVAFLVTTFVFTTVGVVGQSMYPTLRNGERVLVPKWETWLVRLGFMEWRRGEIAILKPPE
GTPFSTARFPVLGFSFRAFFIKRIVAVPGDEVYVDRGVVYVNGKPLAETHITDRITPWPDSFPGVCYEGGRLTRIVTQQG
DFPVELLPAYLRPLKEMLLPPSQETLARSELGEVCEVGRIKLKPGYYFVMGDNRTLGGSEDSRTFGPIPVERIAGRASFV
WWPVVVREEGGFRLNLRALAIPPAYRLE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 30496; Mature: 30496

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFWDYLFKEWFRQVGEALLVAFLVTTFVFTTVGVVGQSMYPTLRNGERVLVPKWETWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECHHHHH
VRLGFMEWRRGEIAILKPPEGTPFSTARFPVLGFSFRAFFIKRIVAVPGDEVYVDRGVVY
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCEEEEECCEEE
VNGKPLAETHITDRITPWPDSFPGVCYEGGRLTRIVTQQGDFPVELLPAYLRPLKEMLLP
ECCCCCCHHHCCCCCCCCCCCCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC
PSQETLARSELGEVCEVGRIKLKPGYYFVMGDNRTLGGSEDSRTFGPIPVERIAGRASFV
CCHHHHHHHHHHHHHHCCCEEECCCEEEEEECCEECCCCCCCCCCCCCCHHHHCCCCEEE
WWPVVVREEGGFRLNLRALAIPPAYRLE
EEEEEEEECCCEEEEEEEEECCCCCCCC
>Mature Secondary Structure
MKAFWDYLFKEWFRQVGEALLVAFLVTTFVFTTVGVVGQSMYPTLRNGERVLVPKWETWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECHHHHH
VRLGFMEWRRGEIAILKPPEGTPFSTARFPVLGFSFRAFFIKRIVAVPGDEVYVDRGVVY
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCCEEEEECCEEE
VNGKPLAETHITDRITPWPDSFPGVCYEGGRLTRIVTQQGDFPVELLPAYLRPLKEMLLP
ECCCCCCHHHCCCCCCCCCCCCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC
PSQETLARSELGEVCEVGRIKLKPGYYFVMGDNRTLGGSEDSRTFGPIPVERIAGRASFV
CCHHHHHHHHHHHHHHCCCEEECCCEEEEEECCEECCCCCCCCCCCCCCHHHHCCCCEEE
WWPVVVREEGGFRLNLRALAIPPAYRLE
EEEEEEEECCCEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 9823656 [H]