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The map label for this gene is glmM [H]

Identifier: 55981025

GI number: 55981025

Start: 1000659

End: 1001972

Strand: Direct

Name: glmM [H]

Synonym: TTHA1056

Alternate gene names: 55981025

Gene position: 1000659-1001972 (Clockwise)

Preceding gene: 55981023

Following gene: 55981026

Centisome position: 54.1

GC content: 70.55

Gene sequence:

>1314_bases
ATGAGGCGCTACTTCGGCACCGACGGGGTGCGGGGGGAGGCAGGGAAGCCCCCTCTTACCCCGGAGTTTGTCCTAAAGCT
CGGCCAGGCGGCGGGGGCCTACTTCCTTGCCCAGGAAAAAAGGCCCGTGGTCCTCCTCGCCAAGGACACCCGGGAGTCCT
CGGACCTCCTGGAGGCCGCCCTGGCGGCGGGGCTTATGAGCCAGGGGGTGCGGGTGGAGCACCTCGGGGTCCTCCCCACC
CCGGGGGTCGCCCACCTCACCAAGGCCCTCAAGGCCACGGCGGGGGCGGTGATCTCGGCGAGCCACAACCCCTACCAGGA
CAACGGCATCAAGTTCTTCGGGCCCACGGGGGAGAAGCTCCCCGACGGGGCCGAGGAGGAGATTGAGCGCCTTCTCCTGG
AAGACCACCCCACCCGGGGGATCGGCACCGTGGGGGACTTCCGGGAGGCGGAGAGGATGTACCTGGACTTCCTCCTCGCC
CACGCCCCGGACCTCACGGGGCTCAAGGTGGGCCTGGACCTCGCCCACGGGGCCACCTACCGCATCGGGCCCAAGCTCTT
CCAGAAGGCGGGGGCCGAGGTCATGGCCTTCTTCAACACCCCGGACGGCCGGAACATCAACCGGGGCTGCGGCTCCACCC
ACCCCGAGGCCTTGAGCCGCTTCGTGGTGGAGCTCGGGCTGGACCTGGGAATCGCCTTTGACGGGGACGGGGACCGGGTG
CAGTTCATAGACCGCAAGGGGCGCCTCTTCCACGGGGACCACGTCCTCTACCTCGCCGCCTTGGCCTTTGGGGAGAAAGG
CGTGGTGGGGACGGTGATGAGCAACATGGCCCTGGAGGTGGCCCTCAAGGAAAGGGGCCTCGCCTTCCACCGGGCGGCGG
TGGGCGACCGGTACGTCCTGGAGAAGCTCAAGGAGACGGGCCTGGCCCTGGGAGGGGAGCCCTCGGGGCACGTGATCTTC
CTCCGCCACCACACCACGGGGGACGGCCTCCTCACCGCCCTCCTCACCCTGAAGGCCCTGAAGGCCCTGGGCGGGGACCT
CGCCGACTGGTACGAGGCGCTTCCCCTCTACCCCCAGGTGCTCCTCAACGTGCGGGTTTCCGACAAGGCCAAGGTGATGG
CGGACCCGAGGCTTGGGGAGGCCGTCCGCGAGGCCGAGGCCCGGCTAGGGGGGAGGGGCCGGGTGAACGTCCGCCCCTCG
GGCACGGAGCCCGTGGTCCGGGTCATGGTGGAGGCGGAGGAGGGGGCGGAGGAGGTGGCGCGGGAGCTCGCCGAGCGCGT
CCGGGCCCTCTCCCAAGAGGCCCAGGCGGTATGA

Upstream 100 bases:

>100_bases
TACTCAGCACATTGAGTAAATCAAGAGGCGGGCCCTGGGTAAGAGCACCCGGCGGAGGGTTCGTCCCACCCGCCCCACGG
GCCCTGGTATAGTGGCCGCC

Downstream 100 bases:

>100_bases
TGGACCCCGATGGCGGAACCCCTCGGCCACTACCAGGAGCAGCGGGTAGGGGTGTTCGTGGACACCCAGAACCTCTACCA
CTCGGCCCGGGACTACTACG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MRRYFGTDGVRGEAGKPPLTPEFVLKLGQAAGAYFLAQEKRPVVLLAKDTRESSDLLEAALAAGLMSQGVRVEHLGVLPT
PGVAHLTKALKATAGAVISASHNPYQDNGIKFFGPTGEKLPDGAEEEIERLLLEDHPTRGIGTVGDFREAERMYLDFLLA
HAPDLTGLKVGLDLAHGATYRIGPKLFQKAGAEVMAFFNTPDGRNINRGCGSTHPEALSRFVVELGLDLGIAFDGDGDRV
QFIDRKGRLFHGDHVLYLAALAFGEKGVVGTVMSNMALEVALKERGLAFHRAAVGDRYVLEKLKETGLALGGEPSGHVIF
LRHHTTGDGLLTALLTLKALKALGGDLADWYEALPLYPQVLLNVRVSDKAKVMADPRLGEAVREAEARLGGRGRVNVRPS
GTEPVVRVMVEAEEGAEEVARELAERVRALSQEAQAV

Sequences:

>Translated_437_residues
MRRYFGTDGVRGEAGKPPLTPEFVLKLGQAAGAYFLAQEKRPVVLLAKDTRESSDLLEAALAAGLMSQGVRVEHLGVLPT
PGVAHLTKALKATAGAVISASHNPYQDNGIKFFGPTGEKLPDGAEEEIERLLLEDHPTRGIGTVGDFREAERMYLDFLLA
HAPDLTGLKVGLDLAHGATYRIGPKLFQKAGAEVMAFFNTPDGRNINRGCGSTHPEALSRFVVELGLDLGIAFDGDGDRV
QFIDRKGRLFHGDHVLYLAALAFGEKGVVGTVMSNMALEVALKERGLAFHRAAVGDRYVLEKLKETGLALGGEPSGHVIF
LRHHTTGDGLLTALLTLKALKALGGDLADWYEALPLYPQVLLNVRVSDKAKVMADPRLGEAVREAEARLGGRGRVNVRPS
GTEPVVRVMVEAEEGAEEVARELAERVRALSQEAQAV
>Mature_437_residues
MRRYFGTDGVRGEAGKPPLTPEFVLKLGQAAGAYFLAQEKRPVVLLAKDTRESSDLLEAALAAGLMSQGVRVEHLGVLPT
PGVAHLTKALKATAGAVISASHNPYQDNGIKFFGPTGEKLPDGAEEEIERLLLEDHPTRGIGTVGDFREAERMYLDFLLA
HAPDLTGLKVGLDLAHGATYRIGPKLFQKAGAEVMAFFNTPDGRNINRGCGSTHPEALSRFVVELGLDLGIAFDGDGDRV
QFIDRKGRLFHGDHVLYLAALAFGEKGVVGTVMSNMALEVALKERGLAFHRAAVGDRYVLEKLKETGLALGGEPSGHVIF
LRHHTTGDGLLTALLTLKALKALGGDLADWYEALPLYPQVLLNVRVSDKAKVMADPRLGEAVREAEARLGGRGRVNVRPS
GTEPVVRVMVEAEEGAEEVARELAERVRALSQEAQAV

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=46.4125560538117, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1788361, Length=446, Percent_Identity=28.6995515695067, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786904, Length=509, Percent_Identity=23.5756385068762, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 46969; Mature: 46969

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRYFGTDGVRGEAGKPPLTPEFVLKLGQAAGAYFLAQEKRPVVLLAKDTRESSDLLEAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHHHHHH
LAAGLMSQGVRVEHLGVLPTPGVAHLTKALKATAGAVISASHNPYQDNGIKFFGPTGEKL
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEECCCCCCC
PDGAEEEIERLLLEDHPTRGIGTVGDFREAERMYLDFLLAHAPDLTGLKVGLDLAHGATY
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEE
RIGPKLFQKAGAEVMAFFNTPDGRNINRGCGSTHPEALSRFVVELGLDLGIAFDGDGDRV
ECCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCEE
QFIDRKGRLFHGDHVLYLAALAFGEKGVVGTVMSNMALEVALKERGLAFHRAAVGDRYVL
EEEECCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHH
EKLKETGLALGGEPSGHVIFLRHHTTGDGLLTALLTLKALKALGGDLADWYEALPLYPQV
HHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHH
LLNVRVSDKAKVMADPRLGEAVREAEARLGGRGRVNVRPSGTEPVVRVMVEAEEGAEEVA
HEEEEECCCCCEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCHHHHH
RELAERVRALSQEAQAV
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRYFGTDGVRGEAGKPPLTPEFVLKLGQAAGAYFLAQEKRPVVLLAKDTRESSDLLEAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHHHHHH
LAAGLMSQGVRVEHLGVLPTPGVAHLTKALKATAGAVISASHNPYQDNGIKFFGPTGEKL
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCEEEECCCCCCC
PDGAEEEIERLLLEDHPTRGIGTVGDFREAERMYLDFLLAHAPDLTGLKVGLDLAHGATY
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEE
RIGPKLFQKAGAEVMAFFNTPDGRNINRGCGSTHPEALSRFVVELGLDLGIAFDGDGDRV
ECCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCEE
QFIDRKGRLFHGDHVLYLAALAFGEKGVVGTVMSNMALEVALKERGLAFHRAAVGDRYVL
EEEECCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHH
EKLKETGLALGGEPSGHVIFLRHHTTGDGLLTALLTLKALKALGGDLADWYEALPLYPQV
HHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHH
LLNVRVSDKAKVMADPRLGEAVREAEARLGGRGRVNVRPSGTEPVVRVMVEAEEGAEEVA
HEEEEECCCCCEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCHHHHH
RELAERVRALSQEAQAV
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788726 [H]