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The map label for this gene is trmI [H]

Identifier: 55980578

GI number: 55980578

Start: 577206

End: 577973

Strand: Reverse

Name: trmI [H]

Synonym: TTHA0609

Alternate gene names: 55980578

Gene position: 577973-577206 (Counterclockwise)

Preceding gene: 55980579

Following gene: 55980577

Centisome position: 31.25

GC content: 70.57

Gene sequence:

>768_bases
GTGGCGTGGCCGGGACCGCTACTCCTCAAAGACCGCAAGGGCCGGGCCTACCTGGTCTTCCCCAAGGAAGGGGGCGTCTT
CCACCACCACAAGGGGAGCGTCCCCCACGAGGCCCTCCTCGAGGCGGGCCCCGGGGGGGTGGTGCGGACCCACCTGGGGG
AGGAGCTTTCCGTCCACCGCCCGACCCTGGAGGAGTACCTCCTCCACATGAAGCGGAGCGCCACCCCCACCTACCCCAAG
GACGCGAGCGCCATGGTGACCCTCCTGGACCTCGCCCCGGGGATGCGGGTCCTCGAGGCGGGCACGGGCTCCGGGGGCCT
CACCCTCTTCCTGGCCCGGGCCGTGGGGGAGAAGGGCCTGGTGGAAAGCTACGAGGCCAGGCCCCACCACCTGGCCCAGG
CGGAACGGAACGTCCGGGCCTTCTGGCAGGTGGAGAACGTCCGCTTCCACCTGGGAAAGCTTGAGGAGGCGGAGCTGGAG
GAGGCGGCCTACGACGGGGTGGCCCTGGACCTGATGGAGCCCTGGAAGGCCCTGGAGAAGGCGGCCCTGGCCCTGAAGCC
GGACCGGTTTCTCGTGGCCTACCTGCCCAACATCACCCAGGTCCTGGAGCTCGTCCGGGCCGCTGAGGCCCACCCCTTCC
GGCTGGAAAGGGTCTTGGAGGTGGGCTGGCGGGAGTGGGAGGTCAGGCTTCCCGTGGCCCACCCCCGGTTCCAGCAGGTG
GGGCACACCGCCTTTCTCGTGGCCCTTAGGCGATGGAAGGCCTCCTGA

Upstream 100 bases:

>100_bases
TCGTGGGGCCCTTCCGCCTCCCGAACCCCTTTGACCTGGAGCGGTACCGGGACTACCTGGCCCTCGCCGAGGCCCTTTAG
GCCTCCCGAGGAGGTGCCCC

Downstream 100 bases:

>100_bases
TCCACGCCGTCTTGCGGGAGCTTGAGAAGGAGCTCCCCGCCCAGAACCTCGGCCTCGCCTTCCCCGAGGAGGGGACGGCG
GCCATCCTCCTCAAGGGCCG

Product: tRNA (adenine-N(1)-)-methyltransferase

Products: NA

Alternate protein names: tRNA(m1A58)-methyltransferase; tRNA(m1A58)MTase [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MAWPGPLLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEALLEAGPGGVVRTHLGEELSVHRPTLEEYLLHMKRSATPTYPK
DASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELE
EAAYDGVALDLMEPWKALEKAALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQV
GHTAFLVALRRWKAS

Sequences:

>Translated_255_residues
MAWPGPLLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEALLEAGPGGVVRTHLGEELSVHRPTLEEYLLHMKRSATPTYPK
DASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELE
EAAYDGVALDLMEPWKALEKAALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQV
GHTAFLVALRRWKAS
>Mature_254_residues
AWPGPLLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEALLEAGPGGVVRTHLGEELSVHRPTLEEYLLHMKRSATPTYPKD
ASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELEE
AAYDGVALDLMEPWKALEKAALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQVG
HTAFLVALRRWKAS

Specific function: Catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. Is required for cell growth at extreme temperatures [H]

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmI family [H]

Homologues:

Organism=Homo sapiens, GI222831587, Length=221, Percent_Identity=35.2941176470588, Blast_Score=131, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 28568; Mature: 28437

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWPGPLLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEALLEAGPGGVVRTHLGEELSVHR
CCCCCCEEEECCCCCEEEEEECCCCEEECCCCCCCHHHHHHCCCCCEEEHHCCCCCCCCC
PTLEEYLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGL
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCC
VESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELEEAAYDGVALDLMEPWKALEK
HHHHCCCCHHHHHHHCCCEEEEEEECCEEECCCCCHHHHHHHHHCCEEEHHHHHHHHHHH
AALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQV
HHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHH
GHTAFLVALRRWKAS
CHHHHHHHHHHHCCC
>Mature Secondary Structure 
AWPGPLLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEALLEAGPGGVVRTHLGEELSVHR
CCCCCEEEECCCCCEEEEEECCCCEEECCCCCCCHHHHHHCCCCCEEEHHCCCCCCCCC
PTLEEYLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGL
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCC
VESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELEEAAYDGVALDLMEPWKALEK
HHHHCCCCHHHHHHHCCCEEEEEEECCEEECCCCCHHHHHHHHHCCEEEHHHHHHHHHHH
AALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQV
HHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHH
GHTAFLVALRRWKAS
CHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA