Click here to switch to the map view.

The map label for this gene is nhaA2 [H]

Identifier: 55980579

GI number: 55980579

Start: 577994

End: 578857

Strand: Reverse

Name: nhaA2 [H]

Synonym: TTHA0610

Alternate gene names: 55980579

Gene position: 578857-577994 (Counterclockwise)

Preceding gene: 55980580

Following gene: 55980578

Centisome position: 31.29

GC content: 74.31

Gene sequence:

>864_bases
ATGAAGCGCCTCGCCGTCCTCCTCCTCGGCCTGGGGGCCGCCTGGGCCCAGATCGCCGCCCCCCTGGAGCGCTTCTCCCC
CGGCCCCCTGCCGGAAGGGGCCCGGATCCAGACGGAGGCCAGGTCCGGCCGCCTCTACGCCGTGCGCTACGAGGGCCCGG
TGAACGCAAGCCTCATGGGCCGGATCCTCTCCGCGGCCACGGGGGTGCCGGGCCACGCCCAGGGCTTCGTGGCCTGGTAC
GGGAAGAACCAAGCCCTCCTCCGCCGGGGCCCCGTGGAGCTCAACGTGGAGGGCGCCTTCCTCCTCAAGCTCGCCGTGGG
GGCCTGGGCCGAGATGGAGGTGCGGCCCCTCCTCACAGAGGAGGCCCTCTTCGGGGAGGACCGGCACGTCCTCGGGGAGA
AGGGGGTGGTGGTCCGGGTCTTCTCCGACTTCCAGTGCCCCTACTGCCAGCGCCTCGCCCGGGAGGTCCTCCCCGCCCTC
AAGGCCATGGCCCGGGAAGGGCGGCTCCGCCTCGCCTACCGCCACTTTCCCCTCTACGAGATCCACCCCGAGGCGGTGCC
CGCGGCGGTGGCCAGCGAGTGCGCCGCGGCCCAGGGGGCCTTCTGGGCCTACCACGACCTCCTCATGGCGGGGTCCGGGT
GGGACTACCCGGCCCTGGCGAGGCGGCTCGGCTTGGACCCCAAGGCCTTCCAGGCCTGCCTCGAGGACCCCGCCTCCCGG
GCCCCGGTGGAGGCGGACCGGGCGCTGGCGGAGAGGCTCGGCCTGCCCGGCACCCCCTCGGTCTTCGTGGGGCCCTTCCG
CCTCCCGAACCCCTTTGACCTGGAGCGGTACCGGGACTACCTGGCCCTCGCCGAGGCCCTTTAG

Upstream 100 bases:

>100_bases
CCTTCGCCGAGGCCCCCGACCCCTTCCTGGCCCAGCCGGTGGAGGTGCAGGTGGGCGGCGCCGTGGTCTTCGTCCTGCCC
GTGGAGCACTTCGTCAAGCT

Downstream 100 bases:

>100_bases
GCCTCCCGAGGAGGTGCCCCGTGGCGTGGCCGGGACCGCTACTCCTCAAAGACCGCAAGGGCCGGGCCTACCTGGTCTTC
CCCAAGGAAGGGGGCGTCTT

Product: hypothetical protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKRLAVLLLGLGAAWAQIAAPLERFSPGPLPEGARIQTEARSGRLYAVRYEGPVNASLMGRILSAATGVPGHAQGFVAWY
GKNQALLRRGPVELNVEGAFLLKLAVGAWAEMEVRPLLTEEALFGEDRHVLGEKGVVVRVFSDFQCPYCQRLAREVLPAL
KAMAREGRLRLAYRHFPLYEIHPEAVPAAVASECAAAQGAFWAYHDLLMAGSGWDYPALARRLGLDPKAFQACLEDPASR
APVEADRALAERLGLPGTPSVFVGPFRLPNPFDLERYRDYLALAEAL

Sequences:

>Translated_287_residues
MKRLAVLLLGLGAAWAQIAAPLERFSPGPLPEGARIQTEARSGRLYAVRYEGPVNASLMGRILSAATGVPGHAQGFVAWY
GKNQALLRRGPVELNVEGAFLLKLAVGAWAEMEVRPLLTEEALFGEDRHVLGEKGVVVRVFSDFQCPYCQRLAREVLPAL
KAMAREGRLRLAYRHFPLYEIHPEAVPAAVASECAAAQGAFWAYHDLLMAGSGWDYPALARRLGLDPKAFQACLEDPASR
APVEADRALAERLGLPGTPSVFVGPFRLPNPFDLERYRDYLALAEAL
>Mature_287_residues
MKRLAVLLLGLGAAWAQIAAPLERFSPGPLPEGARIQTEARSGRLYAVRYEGPVNASLMGRILSAATGVPGHAQGFVAWY
GKNQALLRRGPVELNVEGAFLLKLAVGAWAEMEVRPLLTEEALFGEDRHVLGEKGVVVRVFSDFQCPYCQRLAREVLPAL
KAMAREGRLRLAYRHFPLYEIHPEAVPAAVASECAAAQGAFWAYHDLLMAGSGWDYPALARRLGLDPKAFQACLEDPASR
APVEADRALAERLGLPGTPSVFVGPFRLPNPFDLERYRDYLALAEAL

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 31343; Mature: 31343

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLAVLLLGLGAAWAQIAAPLERFSPGPLPEGARIQTEARSGRLYAVRYEGPVNASLMG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHH
RILSAATGVPGHAQGFVAWYGKNQALLRRGPVELNVEGAFLLKLAVGAWAEMEVRPLLTE
HHHHHHCCCCCCCCCEEEEECCCHHHHCCCCEEEECCHHEEEHHHHCCCCCCEECHHHHH
EALFGEDRHVLGEKGVVVRVFSDFQCPYCQRLAREVLPALKAMAREGRLRLAYRHFPLYE
HHHCCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEE
IHPEAVPAAVASECAAAQGAFWAYHDLLMAGSGWDYPALARRLGLDPKAFQACLEDPASR
ECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
APVEADRALAERLGLPGTPSVFVGPFRLPNPFDLERYRDYLALAEAL
CCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRLAVLLLGLGAAWAQIAAPLERFSPGPLPEGARIQTEARSGRLYAVRYEGPVNASLMG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHH
RILSAATGVPGHAQGFVAWYGKNQALLRRGPVELNVEGAFLLKLAVGAWAEMEVRPLLTE
HHHHHHCCCCCCCCCEEEEECCCHHHHCCCCEEEECCHHEEEHHHHCCCCCCEECHHHHH
EALFGEDRHVLGEKGVVVRVFSDFQCPYCQRLAREVLPALKAMAREGRLRLAYRHFPLYE
HHHCCCCCHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEE
IHPEAVPAAVASECAAAQGAFWAYHDLLMAGSGWDYPALARRLGLDPKAFQACLEDPASR
ECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
APVEADRALAERLGLPGTPSVFVGPFRLPNPFDLERYRDYLALAEAL
CCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA