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The map label for this gene is umuD [H]

Identifier: 54294587

GI number: 54294587

Start: 1857047

End: 1857463

Strand: Reverse

Name: umuD [H]

Synonym: lpl1663

Alternate gene names: 54294587

Gene position: 1857463-1857047 (Counterclockwise)

Preceding gene: 54294593

Following gene: 54294586

Centisome position: 55.52

GC content: 41.01

Gene sequence:

>417_bases
ATGAAATATCTTCAAGGAGAAAAGGAGTTCCCAGCGATTCCTTTATATACCAGTTCTGTAAGAGCTGGTTTTCCTTCTCC
GGGTGATGACTATATTGAATCCATGCTGGATTTGAATGAGTACCTGATCAAGCATCCTGCATCCACATTTTTTGTACGAG
CTTCTGGAGAATCCATGATAAACGCCGGCATTTACTCCGGTGATATTTTAATCGTTGATCGTGGCATAGAGGCTACTCAT
GGAAAAATTGTAATCGTTGCCCTGAATGGCGAATTGACAGTAAAACGTTTATCCCGTCAACATGGGCAAGTTAAGTTACT
GGCTGAAAACCCTGATTTTCCTCCTATAGATATTACAGAGGAATACGATATGGTGATTTGGGGAGTCGTCACACATGTTA
TTCATACGGTATTGTGA

Upstream 100 bases:

>100_bases
TGGTGGTGCACGAGCAGGCGCTGGACGCCCTCGAGGACAAGGTAAATATGGAGAAGCAACCAGATCAGTTCGTATACCTG
AATCTCGTATACAGGATGTG

Downstream 100 bases:

>100_bases
TGTTTGCGCTGGTCGATTGTAATAATTTTTATGTCTCGTGTGAGCGTTTATTTAAACCAGCCTTAGCGAATAAACCAATT
TTGGTCTTGTCTAATAATGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKYLQGEKEFPAIPLYTSSVRAGFPSPGDDYIESMLDLNEYLIKHPASTFFVRASGESMINAGIYSGDILIVDRGIEATH
GKIVIVALNGELTVKRLSRQHGQVKLLAENPDFPPIDITEEYDMVIWGVVTHVIHTVL

Sequences:

>Translated_138_residues
MKYLQGEKEFPAIPLYTSSVRAGFPSPGDDYIESMLDLNEYLIKHPASTFFVRASGESMINAGIYSGDILIVDRGIEATH
GKIVIVALNGELTVKRLSRQHGQVKLLAENPDFPPIDITEEYDMVIWGVVTHVIHTVL
>Mature_138_residues
MKYLQGEKEFPAIPLYTSSVRAGFPSPGDDYIESMLDLNEYLIKHPASTFFVRASGESMINAGIYSGDILIVDRGIEATH
GKIVIVALNGELTVKRLSRQHGQVKLLAENPDFPPIDITEEYDMVIWGVVTHVIHTVL

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=130, Percent_Identity=47.6923076923077, Blast_Score=131, Evalue=2e-32,
Organism=Escherichia coli, GI1790476, Length=137, Percent_Identity=35.036496350365, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 15329; Mature: 15329

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLQGEKEFPAIPLYTSSVRAGFPSPGDDYIESMLDLNEYLIKHPASTFFVRASGESMI
CCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEE
NAGIYSGDILIVDRGIEATHGKIVIVALNGELTVKRLSRQHGQVKLLAENPDFPPIDITE
ECCEECCCEEEEECCCCCCCCEEEEEEECCCEEEHHHHCCCCEEEEEECCCCCCCCCCCC
EYDMVIWGVVTHVIHTVL
CCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYLQGEKEFPAIPLYTSSVRAGFPSPGDDYIESMLDLNEYLIKHPASTFFVRASGESMI
CCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEE
NAGIYSGDILIVDRGIEATHGKIVIVALNGELTVKRLSRQHGQVKLLAENPDFPPIDITE
ECCEECCCEEEEECCCCCCCCEEEEEEECCCEEEHHHHCCCCEEEEEECCCCCCCCCCCC
EYDMVIWGVVTHVIHTVL
CCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]