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The map label for this gene is umuC [H]

Identifier: 54294586

GI number: 54294586

Start: 1855791

End: 1857047

Strand: Reverse

Name: umuC [H]

Synonym: lpl1662

Alternate gene names: 54294586

Gene position: 1857047-1855791 (Counterclockwise)

Preceding gene: 54294587

Following gene: 54294583

Centisome position: 55.51

GC content: 39.06

Gene sequence:

>1257_bases
ATGTTTGCGCTGGTCGATTGTAATAATTTTTATGTCTCGTGTGAGCGTTTATTTAAACCAGCCTTAGCGAATAAACCAAT
TTTGGTCTTGTCTAATAATGATGGTTGTGTGATTGCGCGATCTAATGAAGTAAAAGCTTTGGGTGTTCAAATGGGAGTAC
CTTATTTTGCAGTCAAAGCATTATGCAAGCAGCATAAAGTGCATGTGTTTTCATCCAATTACACATTGTATGCTGATATG
TCACGTCGGGTTATGTCAGTTCTTGAAGACAATTGGCCAGCAATAGAGATTTACTCCATTGATGAAGCTTTTCTTGATTT
GAATACTTTGCCCCAATCTGAACATAATGAGTTTTGTCGCAAGTTACAGAAAATTGTTTTGCGCTATACCGGTATTCCCG
TATCCATAGGCATAGGGGCAACCAAAACCCTGGCTAAACTCGCAAACCATATTGCGAAAAAGGAATTAAGAACTCCTGTG
TTTAACATTGAAAATCAATATCATTGGTTAGCTAAAATAGTTGTTGGCGAGGTATGGGGGATAGGGCGGCAATGGGGTAA
AAAGTTAGTACAACAGGGAATTTATACAGCTCATGACTTGGCTGGTATGGATTTGCAATTAATTAAAAAATTATTTAGTG
TTGTATTGCAACGAACAGTGCTTGAGTTGCGTGGGGTTTCATGTGGCAGTTTACAGGATTTTGAATCAAGAAAAAGCATA
ATATCTTCCAAATCCTTTGGTTCTATGCAAACAGAGTATTCTGCTCTTGCTCAGGCCATCAGCAGCCATTGTGCCAGAGC
TTGGGAAAAGTTACGTCATCAAAAATTGATGGCATGCCATCTTTCCATATTTATCAAAACCAATCGATTCCGTTTGGATT
TGCCACAATATCAGCAAACTATAGGGTTTAAGTTGATTAATCCAACTGATGATCTGCGACATTTAATTCGTTGTGCCAAA
TTGTGCCTGCGTAAAATATTTCGTCCTGGATTCCATTACCAAAAGGTAGGCATATATTTGGGAGATTTAATTGAAAAAAA
CTGTTTGCAACTGGATCTGTTTAACCAAGTTTCAGAGAAAGAGTTAAATCAGGCAGAGCGATTGATGTCGGTATTAGGTG
CAATCAATACGAAATATGGCCGTCATACCTTACGTTTGGCAGCAGAAGGATATGTGAAGCCTTGGGCTATGCGGGCACAG
TTACGTTCTCCCAGCTATACCACTTCCTGGTCTGAATTGCCTGTGGTCATTATTTAA

Upstream 100 bases:

>100_bases
TACTGGCTGAAAACCCTGATTTTCCTCCTATAGATATTACAGAGGAATACGATATGGTGATTTGGGGAGTCGTCACACAT
GTTATTCATACGGTATTGTG

Downstream 100 bases:

>100_bases
AGAGAAATTTATAGGTACTATGTCATCCGGGAAATCATGTTAGGTCACCCGGATGACAGCCTGGTTTAATAACCCAGGCT
GGAAGTTAATGTCGAACAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MFALVDCNNFYVSCERLFKPALANKPILVLSNNDGCVIARSNEVKALGVQMGVPYFAVKALCKQHKVHVFSSNYTLYADM
SRRVMSVLEDNWPAIEIYSIDEAFLDLNTLPQSEHNEFCRKLQKIVLRYTGIPVSIGIGATKTLAKLANHIAKKELRTPV
FNIENQYHWLAKIVVGEVWGIGRQWGKKLVQQGIYTAHDLAGMDLQLIKKLFSVVLQRTVLELRGVSCGSLQDFESRKSI
ISSKSFGSMQTEYSALAQAISSHCARAWEKLRHQKLMACHLSIFIKTNRFRLDLPQYQQTIGFKLINPTDDLRHLIRCAK
LCLRKIFRPGFHYQKVGIYLGDLIEKNCLQLDLFNQVSEKELNQAERLMSVLGAINTKYGRHTLRLAAEGYVKPWAMRAQ
LRSPSYTTSWSELPVVII

Sequences:

>Translated_418_residues
MFALVDCNNFYVSCERLFKPALANKPILVLSNNDGCVIARSNEVKALGVQMGVPYFAVKALCKQHKVHVFSSNYTLYADM
SRRVMSVLEDNWPAIEIYSIDEAFLDLNTLPQSEHNEFCRKLQKIVLRYTGIPVSIGIGATKTLAKLANHIAKKELRTPV
FNIENQYHWLAKIVVGEVWGIGRQWGKKLVQQGIYTAHDLAGMDLQLIKKLFSVVLQRTVLELRGVSCGSLQDFESRKSI
ISSKSFGSMQTEYSALAQAISSHCARAWEKLRHQKLMACHLSIFIKTNRFRLDLPQYQQTIGFKLINPTDDLRHLIRCAK
LCLRKIFRPGFHYQKVGIYLGDLIEKNCLQLDLFNQVSEKELNQAERLMSVLGAINTKYGRHTLRLAAEGYVKPWAMRAQ
LRSPSYTTSWSELPVVII
>Mature_418_residues
MFALVDCNNFYVSCERLFKPALANKPILVLSNNDGCVIARSNEVKALGVQMGVPYFAVKALCKQHKVHVFSSNYTLYADM
SRRVMSVLEDNWPAIEIYSIDEAFLDLNTLPQSEHNEFCRKLQKIVLRYTGIPVSIGIGATKTLAKLANHIAKKELRTPV
FNIENQYHWLAKIVVGEVWGIGRQWGKKLVQQGIYTAHDLAGMDLQLIKKLFSVVLQRTVLELRGVSCGSLQDFESRKSI
ISSKSFGSMQTEYSALAQAISSHCARAWEKLRHQKLMACHLSIFIKTNRFRLDLPQYQQTIGFKLINPTDDLRHLIRCAK
LCLRKIFRPGFHYQKVGIYLGDLIEKNCLQLDLFNQVSEKELNQAERLMSVLGAINTKYGRHTLRLAAEGYVKPWAMRAQ
LRSPSYTTSWSELPVVII

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=420, Percent_Identity=47.3809523809524, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 47614; Mature: 47614

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALVDCNNFYVSCERLFKPALANKPILVLSNNDGCVIARSNEVKALGVQMGVPYFAVKA
CEEEEECCCHHEEHHHHHHHHHCCCCEEEEECCCCEEEEECCCCEEEEHHHCCHHHHHHH
LCKQHKVHVFSSNYTLYADMSRRVMSVLEDNWPAIEIYSIDEAFLDLNTLPQSEHNEFCR
HHHHCCEEEEECCEEEEEHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCHHHHHHH
KLQKIVLRYTGIPVSIGIGATKTLAKLANHIAKKELRTPVFNIENQYHWLAKIVVGEVWG
HHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
IGRQWGKKLVQQGIYTAHDLAGMDLQLIKKLFSVVLQRTVLELRGVSCGSLQDFESRKSI
CHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ISSKSFGSMQTEYSALAQAISSHCARAWEKLRHQKLMACHLSIFIKTNRFRLDLPQYQQT
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEECCHHHHHH
IGFKLINPTDDLRHLIRCAKLCLRKIFRPGFHYQKVGIYLGDLIEKNCLQLDLFNQVSEK
HCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNQAERLMSVLGAINTKYGRHTLRLAAEGYVKPWAMRAQLRSPSYTTSWSELPVVII
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEEC
>Mature Secondary Structure
MFALVDCNNFYVSCERLFKPALANKPILVLSNNDGCVIARSNEVKALGVQMGVPYFAVKA
CEEEEECCCHHEEHHHHHHHHHCCCCEEEEECCCCEEEEECCCCEEEEHHHCCHHHHHHH
LCKQHKVHVFSSNYTLYADMSRRVMSVLEDNWPAIEIYSIDEAFLDLNTLPQSEHNEFCR
HHHHCCEEEEECCEEEEEHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCHHHHHHH
KLQKIVLRYTGIPVSIGIGATKTLAKLANHIAKKELRTPVFNIENQYHWLAKIVVGEVWG
HHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
IGRQWGKKLVQQGIYTAHDLAGMDLQLIKKLFSVVLQRTVLELRGVSCGSLQDFESRKSI
CHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ISSKSFGSMQTEYSALAQAISSHCARAWEKLRHQKLMACHLSIFIKTNRFRLDLPQYQQT
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEECCHHHHHH
IGFKLINPTDDLRHLIRCAKLCLRKIFRPGFHYQKVGIYLGDLIEKNCLQLDLFNQVSEK
HCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELNQAERLMSVLGAINTKYGRHTLRLAAEGYVKPWAMRAQLRSPSYTTSWSELPVVII
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2989817; 2989816; 8905232; 9278503; 1320188 [H]