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The map label for this gene is rtn [H]

Identifier: 54294490

GI number: 54294490

Start: 1737443

End: 1739041

Strand: Direct

Name: rtn [H]

Synonym: lpl1559

Alternate gene names: 54294490

Gene position: 1737443-1739041 (Clockwise)

Preceding gene: 54294488

Following gene: 54294491

Centisome position: 51.93

GC content: 32.15

Gene sequence:

>1599_bases
ATGAGTAAGGTTATTCACAAATTATCTTTATTTCTTTTTAAGAAATTTAAAATCATATGGATTCTCTTAACTATTGGTAT
CCTGATTTCAGCTTTTTATGCTAATTGGAATATTAACCAAAAAAGAGCTTATAAAGATTTAAAAGAAGTTGCAATCAATC
TCAGCAACAACATAGATGGTTTTATCGAAGATCTACTTCAGGAAATCTATGCTTTGCCTGTATATGGGAAAAAAATTGTC
GATTGTAAATCAGATTTATATCCATTCTTGGAACATATCACTCTGAATAATCCTAAAATCTCTGGTGTAATTATTAGTGA
CAACAAGCACAATCAATTTTGTTCAACTTTACCCAATAATAAAGATCTTATTGCAACACCGATTCGTTCACGTTCTATTA
TAGGCCCCTATAATTTACCATTATTTGACCAGCCCGTTTATCTGATCCAGCAAAAAATGGGCAATTACCTTATAGGTGTT
TTAGTTATTGCTTCTGTCTTAAAAAGTGAATTACAAACAGATAAAAATCAATCCACTTCTATAGCCCTATATAATGAATA
TGAGAAAAAAAATATCTTTCGTATTCGATATACTGAACAAAATAAAAACTGGGTATTAAGCAATACGCAAGAAACTGACA
CACAATATACCCCATTAGGTCTCGTTGCTATAGAAAAACTACAAAGCATAAATGGTGTTTCTGTCGTTGTTTCTGAAAAC
AATAAAACCATCCGTCATAACTTTTGGTATGGTCAAACAATAACCATTCTTATTATTTTGATCTGTTCCTTTATTTTGTA
TGCCCTTATAAAAAACATGATGACCAAACGTTATTCATTGCAAGGTGCAATAAAACTGGCCATTAAAAATGAGGAATTTT
ATCCGGTATATCAACCTTTGTTTGATTGTGATGAAGAACGGTTCACAGGGGTTGAAGTATTATTGCGATGGGAAAATGAA
GACAGTCAAATCATTATGCCTGATTTTTTTATTGCTGAAGCAGAAGCTACCGGGTTAATTGTGCCAATTACTCTTCAAAT
CATAGAAATTGCCTGCAAAGAATTTAGATCTCTATTAGAAGAACGTTCTTACTTCCACCTTGCATTTAACATTTCTGCAC
TACATTTCACAGATTCAGTATTTTTCAATCAATTCCATAAGCTAATAGAAAAATATAATATTTCACCGCATCAAATAATC
TTTGAAATTACTGAAAGAGAGCTCCTCGACAAAAACGACACCACTTTTATCAATAAAATGCAAGAACTAAGGCAAGCAGG
TTTTTCACTTGCTGTTGATGATTATGGGACTGGCCATGCCAGCATTAGTTATTTGCAACATTTTCCATTCAATTATTTAA
AAATTGATAAATTATTTGTTCAAGCAATTGGTTCTAATGATATTATCGAATCATTAAATGACGCCATTATCCAGATGGCA
AAAGGATTAAACTTAGTTACTATAGCAGAAGGCGTGGAAACAAAAGACCAAGCTAATTACCTGGCAAATAATGGTGTTCG
TTTACAACAAGGCTGGTATTATTCCAAAGGGCTATCCATTGCTGAATTAACAGCCTTGCTTAAAGGAGAAAAAATATGA

Upstream 100 bases:

>100_bases
TGTCATAATAACTGTTGTAACACAGATAAAAAAATTATTGGGAAATTAGCAGAAATCACATTAAACTCTATAGAAGAAGC
CTATAACAAAGCTCAAGGAT

Downstream 100 bases:

>100_bases
GGAATTATATTTTTTATGGTTTACTACTATTAATTGGTTTATCCCATCAAGGCTTTACTGCCCCAATGATGAAAAAAGGA
AGTTATTGGAAATGCGTAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDGFIEDLLQEIYALPVYGKKIV
DCKSDLYPFLEHITLNNPKISGVIISDNKHNQFCSTLPNNKDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGV
LVIASVLKSELQTDKNQSTSIALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTPLGLVAIEKLQSINGVSVVVSEN
NKTIRHNFWYGQTITILIILICSFILYALIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPLFDCDEERFTGVEVLLRWENE
DSQIIMPDFFIAEAEATGLIVPITLQIIEIACKEFRSLLEERSYFHLAFNISALHFTDSVFFNQFHKLIEKYNISPHQII
FEITERELLDKNDTTFINKMQELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI

Sequences:

>Translated_532_residues
MSKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDGFIEDLLQEIYALPVYGKKIV
DCKSDLYPFLEHITLNNPKISGVIISDNKHNQFCSTLPNNKDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGV
LVIASVLKSELQTDKNQSTSIALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTPLGLVAIEKLQSINGVSVVVSEN
NKTIRHNFWYGQTITILIILICSFILYALIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPLFDCDEERFTGVEVLLRWENE
DSQIIMPDFFIAEAEATGLIVPITLQIIEIACKEFRSLLEERSYFHLAFNISALHFTDSVFFNQFHKLIEKYNISPHQII
FEITERELLDKNDTTFINKMQELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI
>Mature_531_residues
SKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDGFIEDLLQEIYALPVYGKKIVD
CKSDLYPFLEHITLNNPKISGVIISDNKHNQFCSTLPNNKDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGVL
VIASVLKSELQTDKNQSTSIALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTPLGLVAIEKLQSINGVSVVVSENN
KTIRHNFWYGQTITILIILICSFILYALIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPLFDCDEERFTGVEVLLRWENED
SQIIMPDFFIAEAEATGLIVPITLQIIEIACKEFRSLLEERSYFHLAFNISALHFTDSVFFNQFHKLIEKYNISPHQIIF
EITERELLDKNDTTFINKMQELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMAK
GLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=290, Percent_Identity=35.5172413793103, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=36.4341085271318, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI87081845, Length=278, Percent_Identity=31.6546762589928, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87081743, Length=291, Percent_Identity=31.9587628865979, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1790496, Length=248, Percent_Identity=35.0806451612903, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=37.2881355932203, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081921, Length=262, Percent_Identity=35.8778625954198, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI226510982, Length=248, Percent_Identity=33.4677419354839, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1787541, Length=235, Percent_Identity=31.9148936170213, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=29.7520661157025, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=26.7489711934156, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082096, Length=254, Percent_Identity=25.9842519685039, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787410, Length=122, Percent_Identity=29.5081967213115, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 61135; Mature: 61004

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCH
FIEDLLQEIYALPVYGKKIVDCKSDLYPFLEHITLNNPKISGVIISDNKHNQFCSTLPNN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHCCCCC
KDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGVLVIASVLKSELQTDKNQSTS
CCEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTPLGLVAIEKLQSINGVSVVVSEN
EEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
NKTIRHNFWYGQTITILIILICSFILYALIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPL
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHH
FDCDEERFTGVEVLLRWENEDSQIIMPDFFIAEAEATGLIVPITLQIIEIACKEFRSLLE
HCCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
ERSYFHLAFNISALHFTDSVFFNQFHKLIEKYNISPHQIIFEITERELLDKNDTTFINKM
HCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHHHHCCCCCHHHHHHH
QELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
HHHHHCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI
CCCCEEEEECCCCCCHHHHHHHCCCEEEECCEEECCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SKVIHKLSLFLFKKFKIIWILLTIGILISAFYANWNINQKRAYKDLKEVAINLSNNIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCH
FIEDLLQEIYALPVYGKKIVDCKSDLYPFLEHITLNNPKISGVIISDNKHNQFCSTLPNN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHCCCCC
KDLIATPIRSRSIIGPYNLPLFDQPVYLIQQKMGNYLIGVLVIASVLKSELQTDKNQSTS
CCEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IALYNEYEKKNIFRIRYTEQNKNWVLSNTQETDTQYTPLGLVAIEKLQSINGVSVVVSEN
EEEEECCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECC
NKTIRHNFWYGQTITILIILICSFILYALIKNMMTKRYSLQGAIKLAIKNEEFYPVYQPL
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHH
FDCDEERFTGVEVLLRWENEDSQIIMPDFFIAEAEATGLIVPITLQIIEIACKEFRSLLE
HCCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHH
ERSYFHLAFNISALHFTDSVFFNQFHKLIEKYNISPHQIIFEITERELLDKNDTTFINKM
HCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHCCCHHHEEEEEHHHHHCCCCCHHHHHHH
QELRQAGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMA
HHHHHCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI
CCCCEEEEECCCCCCHHHHHHHCCCEEEECCEEECCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]