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The map label for this gene is dtpA [H]

Identifier: 54294424

GI number: 54294424

Start: 1660967

End: 1662454

Strand: Direct

Name: dtpA [H]

Synonym: lpl1493

Alternate gene names: 54294424

Gene position: 1660967-1662454 (Clockwise)

Preceding gene: 54294423

Following gene: 54294425

Centisome position: 49.65

GC content: 36.76

Gene sequence:

>1488_bases
ATGCCCCAAGGTACATTTGCATTATTTTTTATACAAGTGGTTTCTACTTTAAGCTTTAGTGTTCTTTATTCAACTCTTGT
ATTGTACATGAAAGGTAAACTTGGTTTACCCATAGCCACAGCAAACAGCATCATGGGCGTATTTATTGCCTACAATTTTG
CGCTGCATCTGTTAGGTGGTTTTTGGGGAGGCAGACTGCTCTCCAATCGCTCCTTATTTTGTGTTGGGATGATCGCGCAA
ATTTTAGGATGTGTTTTGCTCTCTATAGGAAATACAACTTTTTTATATTATGGCTTGGCTGCATTCTTAACAGGTTCAGG
GTTAAATGTAACATGTGTAAATTGTATGCTGACTCAGCAATTTACACCTGAAGACTCTCGAAGAGAAACCGCATTTCTCT
GGAATTATGCGGGAATGAATATTGGCTTTTTTATTGGATTTAGCCTCAGTGGGGCGTTCCAGATTTCTCAAAACTATCAA
AGGCTTTTTCTTTTAAGCAGTTTAGGTAATCTTGTTGCTTTGCTTATATGCCTTTATTTCTGGCAACAATTACATGATAA
AAACACTACTTACTCAAGAAAGGACAAACCTGCACAAAGAAAAGCAACAGCATTGGGGATTGGGCTAATTTTTGTACTTC
CATTTATTTTAAGACAATTATTGCAGTATGCTGATTGGGCCAATAAATTGGTTATTGTCACTGGAATTATTATGCTCATA
TTAATCTTGATATTAGCCCAACAACAATCTACAAAAGAAGCAAGAGACAAGATTTATGGATTTGCAGTATTAATGTTGGT
TGGTACTGTATTTTGGATGTTATATCAAATTGGCCCAATGGGGTTAACAGTATTCATTGACCATAATGTGCAACGACAAT
ATGGTAATTGGATTATTCCGCCACAGTGGTTTCAAAATATTAATACAGTAGTCATAGTATTCGGAGGGCCACTATTGGGT
TTCATCTTAAATAGAATGCGTCAAAATGGATCTCAGATAAATATTCCTACTCAATTTGCTTTCGCATTATTTTTTATAGG
GGTTGCTTTTGCTATCTTACCAATAGGTATCAATTACGCTAATCAGCATGGTATGGTTAATCCGGGTTGGGTAGTAATAA
GCTTTATATTACAAAGTATTGGCGAACTTCTAATATCTCCAATTGGCTATGCGATGATAGGAGCGTTAGCCCCAACCTCA
CTCCAGGGGGTCATGATGGGAATGTGGATGCTGAATACTGGAGTTGGCGCCACTCTATCCAGTTATAGCTCAAACTTAAT
GATTATTGGTCAAGAAAGTACTTCTCCTTTATTAACTAATGAGGGTTACAGTCATGTCTTTTTGATGCTTGGTTTGTTTG
CAATAGGATCATCCGTTATCCTTTTCATTTTAGTGCCTAAACTAAGAAAGCTGATCAAAGAAAAAAACTTGAATGGCTTT
AAACAGTCTGGCTTAGAGGTAACTGAAAGAGTAGCTTTATGTGAGTAG

Upstream 100 bases:

>100_bases
TTGTCCACAAGGGTTAGTGTTAATATTCAAGAAGAGCTCAACTAGCAAGGGAAAGCATACAATGTTGATTTTGAGTAAAA
GAAGAGGACTATGGAGTTCC

Downstream 100 bases:

>100_bases
TCCCTTTGTCCCAATTATAACGGCAGATATCGATTGGCGTGATGATCTGCCGTATTCCTTACAATTTGATGATATTTACT
ATTCTGCTGAAGGTGGAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MPQGTFALFFIQVVSTLSFSVLYSTLVLYMKGKLGLPIATANSIMGVFIAYNFALHLLGGFWGGRLLSNRSLFCVGMIAQ
ILGCVLLSIGNTTFLYYGLAAFLTGSGLNVTCVNCMLTQQFTPEDSRRETAFLWNYAGMNIGFFIGFSLSGAFQISQNYQ
RLFLLSSLGNLVALLICLYFWQQLHDKNTTYSRKDKPAQRKATALGIGLIFVLPFILRQLLQYADWANKLVIVTGIIMLI
LILILAQQQSTKEARDKIYGFAVLMLVGTVFWMLYQIGPMGLTVFIDHNVQRQYGNWIIPPQWFQNINTVVIVFGGPLLG
FILNRMRQNGSQINIPTQFAFALFFIGVAFAILPIGINYANQHGMVNPGWVVISFILQSIGELLISPIGYAMIGALAPTS
LQGVMMGMWMLNTGVGATLSSYSSNLMIIGQESTSPLLTNEGYSHVFLMLGLFAIGSSVILFILVPKLRKLIKEKNLNGF
KQSGLEVTERVALCE

Sequences:

>Translated_495_residues
MPQGTFALFFIQVVSTLSFSVLYSTLVLYMKGKLGLPIATANSIMGVFIAYNFALHLLGGFWGGRLLSNRSLFCVGMIAQ
ILGCVLLSIGNTTFLYYGLAAFLTGSGLNVTCVNCMLTQQFTPEDSRRETAFLWNYAGMNIGFFIGFSLSGAFQISQNYQ
RLFLLSSLGNLVALLICLYFWQQLHDKNTTYSRKDKPAQRKATALGIGLIFVLPFILRQLLQYADWANKLVIVTGIIMLI
LILILAQQQSTKEARDKIYGFAVLMLVGTVFWMLYQIGPMGLTVFIDHNVQRQYGNWIIPPQWFQNINTVVIVFGGPLLG
FILNRMRQNGSQINIPTQFAFALFFIGVAFAILPIGINYANQHGMVNPGWVVISFILQSIGELLISPIGYAMIGALAPTS
LQGVMMGMWMLNTGVGATLSSYSSNLMIIGQESTSPLLTNEGYSHVFLMLGLFAIGSSVILFILVPKLRKLIKEKNLNGF
KQSGLEVTERVALCE
>Mature_494_residues
PQGTFALFFIQVVSTLSFSVLYSTLVLYMKGKLGLPIATANSIMGVFIAYNFALHLLGGFWGGRLLSNRSLFCVGMIAQI
LGCVLLSIGNTTFLYYGLAAFLTGSGLNVTCVNCMLTQQFTPEDSRRETAFLWNYAGMNIGFFIGFSLSGAFQISQNYQR
LFLLSSLGNLVALLICLYFWQQLHDKNTTYSRKDKPAQRKATALGIGLIFVLPFILRQLLQYADWANKLVIVTGIIMLIL
ILILAQQQSTKEARDKIYGFAVLMLVGTVFWMLYQIGPMGLTVFIDHNVQRQYGNWIIPPQWFQNINTVVIVFGGPLLGF
ILNRMRQNGSQINIPTQFAFALFFIGVAFAILPIGINYANQHGMVNPGWVVISFILQSIGELLISPIGYAMIGALAPTSL
QGVMMGMWMLNTGVGATLSSYSSNLMIIGQESTSPLLTNEGYSHVFLMLGLFAIGSSVILFILVPKLRKLIKEKNLNGFK
QSGLEVTERVALCE

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=477, Percent_Identity=27.8825995807128, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789911, Length=478, Percent_Identity=26.7782426778243, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1790572, Length=492, Percent_Identity=27.0325203252033, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1786927, Length=422, Percent_Identity=23.9336492890995, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54760; Mature: 54629

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00589 PTS_HPR_SER ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGTFALFFIQVVSTLSFSVLYSTLVLYMKGKLGLPIATANSIMGVFIAYNFALHLLGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHH
FWGGRLLSNRSLFCVGMIAQILGCVLLSIGNTTFLYYGLAAFLTGSGLNVTCVNCMLTQQ
HHCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECC
FTPEDSRRETAFLWNYAGMNIGFFIGFSLSGAFQISQNYQRLFLLSSLGNLVALLICLYF
CCCCCCCCCEEEEEEECCCCEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
WQQLHDKNTTYSRKDKPAQRKATALGIGLIFVLPFILRQLLQYADWANKLVIVTGIIMLI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LILILAQQQSTKEARDKIYGFAVLMLVGTVFWMLYQIGPMGLTVFIDHNVQRQYGNWIIP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCC
PQWFQNINTVVIVFGGPLLGFILNRMRQNGSQINIPTQFAFALFFIGVAFAILPIGINYA
HHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCC
NQHGMVNPGWVVISFILQSIGELLISPIGYAMIGALAPTSLQGVMMGMWMLNTGVGATLS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHH
SYSSNLMIIGQESTSPLLTNEGYSHVFLMLGLFAIGSSVILFILVPKLRKLIKEKNLNGF
HCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KQSGLEVTERVALCE
HHCCHHHHHHHHCCC
>Mature Secondary Structure 
PQGTFALFFIQVVSTLSFSVLYSTLVLYMKGKLGLPIATANSIMGVFIAYNFALHLLGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHHHH
FWGGRLLSNRSLFCVGMIAQILGCVLLSIGNTTFLYYGLAAFLTGSGLNVTCVNCMLTQQ
HHCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECC
FTPEDSRRETAFLWNYAGMNIGFFIGFSLSGAFQISQNYQRLFLLSSLGNLVALLICLYF
CCCCCCCCCEEEEEEECCCCEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
WQQLHDKNTTYSRKDKPAQRKATALGIGLIFVLPFILRQLLQYADWANKLVIVTGIIMLI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LILILAQQQSTKEARDKIYGFAVLMLVGTVFWMLYQIGPMGLTVFIDHNVQRQYGNWIIP
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCC
PQWFQNINTVVIVFGGPLLGFILNRMRQNGSQINIPTQFAFALFFIGVAFAILPIGINYA
HHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCC
NQHGMVNPGWVVISFILQSIGELLISPIGYAMIGALAPTSLQGVMMGMWMLNTGVGATLS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHH
SYSSNLMIIGQESTSPLLTNEGYSHVFLMLGLFAIGSSVILFILVPKLRKLIKEKNLNGF
HCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KQSGLEVTERVALCE
HHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]