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The map label for this gene is htpG [H]

Identifier: 54294255

GI number: 54294255

Start: 1476381

End: 1478252

Strand: Direct

Name: htpG [H]

Synonym: lpl1320

Alternate gene names: 54294255

Gene position: 1476381-1478252 (Clockwise)

Preceding gene: 54294254

Following gene: 54294259

Centisome position: 44.13

GC content: 37.87

Gene sequence:

>1872_bases
ATGGTTAGCAAGCAGCAAACTATGGGATTTCAAACAGAAGTAAAGCAAATGCTTCATTTGGTTGTGCATTCTCTATATAG
CAACAAAGAGATTTTTCTTAGAGAATTAATTTCTAATGCTTCTGATGCCTTGGACAAGTTACGATTTTTAGCTTTATCAA
ACGGTTCATTGTTTGAAAATGATTCTGATTTGAAAATTAGCATCCAGATTAATGAAAAGCTTCAAACCATTACCATCAGC
GATAATGGGATTGGTCTGAGTTGGGAAGAGGCAGTAGAAAATTTGGGGACAATTGCAAAATCCGGAACAAAAGAATTTAT
TAGCCAATTAACTGGTGAACAAGCAAAGGATTCTCAACTAATAGGACAGTTTGGAGTGGGTTTTTATTCCGCGTTTATCG
TTGCTGATAAAGTAACAGTTAAAAGTCGCCGCGCTGGGTTACAACCTGAAGATGGAATTGTATGGGAGTCTAAGGGTGAT
GGTGAATTTACTATAGGATATGAAAAAAAATCGACCCGCGGCACAGAAATTACCTTGCACTTAAAACCTGAAAACGACGA
GTTTTTAAGTGATTGGCGTATTCGCGGTATTATTAGTAAATACTCTGATCATATTTGTTGGCCTATTGTGATGAAAAAGC
TTTCAGAGGAAGGCAAGGAATCAAAAGAATTTGAAACAGTAAACAAGGCGACGGCACTTTGGACATTACAGAAATCTGAA
ATTGGCGAAGAAGACTATAAGCAACTGTATAAACATATTTCTCATGATTACATGGATCCATTAACCTGGTCTCATAACCA
TGTTGAAGGAAAACACGAGTATATTACTTTGCTTTACATACCAGCCCATGCCCCATTTGATTTATGGCAGCATGAAGCCA
AACATGGGCTAAAGCTTTATGTAAAGCGTGTATTTATTATGGATGAAGCGACACAATTTTTACCCCGATATTTACGATTT
ATAAAAGGGATTGTGGATGCCAGTGATTTACCGCTTAATATTTCTCGAGAAATATTACAGGATAACAAGCAGGTAGAATC
TATTCGAGCTGCATGCACCAAACGTGTTTTGTCTATGCTTGAAAAAATGGCTACCAATGATAAAGAAACCTATCAGAAGT
TTTGGAATGAATTTGGGCTTGTGCTAAAAGAAGGACCTATTGAGGATTTCGCTAATAAGGAAGCGATTGCCAAGTTGCTT
CGTTTTTCTACTACAGCAAGCGGTAGTGAGAAACAAGAAGTATCGCTGGAGGAATATGTTAGTCGCATGAAAGAAGGGCA
GGATAAAATTTATTATATTACCGCATCGAGCTACAATGCTGCTAAAAATAGTCCTCATTTGGAAATATTCAGGAAAAAGG
GAATTGAGGTATTATTGCTCAGTGATAAAGTCGATGAATGGCTTGTAGGTTATATGAATGAATTTACAGGCAAAAAACTA
CAGTCAATTTCAAAAGGCAAGGTTGAATTGGGGGATGATGAAACTTCCGAACAAATTAAAGAACAGGAAAAAACTCTGGA
GCCATTGATTAAGCATATTAAATCAGTTCTCAATGAGCGAGTTAAAGATGTATTACTGACTAATCGTCTTACTGATTCCC
CTGCATGTGTTGTTGCTGATGAGCAAGACATGGGATTGGAAATGCAAAGAATTTTGCAAGCTGCAGGTCAACAGATTCCA
GTGAGCAAACCTATTTTTGAAATCAATCCGGAGCATGCCCTGATTAAGCGGTTGCATGATATTCAGGATGACAACCAATT
CGAATTATGGGTTACTATGCTGTTTGAACAAGCTGTGTTGGCAGAAGGAGGGCAATTGGATAATCCCGCTGATTTTGTGA
ATCGGGTTAACAGACTCCTGGTTTCCTCCTAG

Upstream 100 bases:

>100_bases
TTTTCTCCTTTTTTAGCGCTATCCCCTTGAAATTCAATAGATCAACCCTATATGAGAAGGTAATTATTACGAACACAACT
ATTAACGGGGAGATTGTTTA

Downstream 100 bases:

>100_bases
AATTCTATAGGGCTGGCAAGCAATCCCGGATTAGAACAAATCATTATCCGGGATGAGCTGAACATAAAATAAAAAGGCTC
AAAAATGAGCCTTTTTATTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKSTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
IGEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
IKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFTGKKL
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQIP
VSKPIFEINPEHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS

Sequences:

>Translated_623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKSTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
IGEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
IKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFTGKKL
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQIP
VSKPIFEINPEHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS
>Mature_623_residues
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFENDSDLKISIQINEKLQTITIS
DNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQLIGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGD
GEFTIGYEKKSTRGTEITLHLKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
IGEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLYVKRVFIMDEATQFLPRYLRF
IKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSMLEKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLL
RFSTTASGSEKQEVSLEEYVSRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFTGKKL
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVADEQDMGLEMQRILQAAGQQIP
VSKPIFEINPEHALIKRLHDIQDDNQFELWVTMLFEQAVLAEGGQLDNPADFVNRVNRLLVSS

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=630, Percent_Identity=37.1428571428571, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=38.7254901960784, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=38.7254901960784, Blast_Score=274, Evalue=2e-73,
Organism=Homo sapiens, GI4507677, Length=416, Percent_Identity=36.5384615384615, Blast_Score=272, Evalue=9e-73,
Organism=Homo sapiens, GI20149594, Length=216, Percent_Identity=43.9814814814815, Blast_Score=183, Evalue=4e-46,
Organism=Escherichia coli, GI1786679, Length=621, Percent_Identity=61.8357487922705, Blast_Score=815, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=671, Percent_Identity=39.344262295082, Blast_Score=452, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17542208, Length=674, Percent_Identity=36.2017804154303, Blast_Score=405, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI115535205, Length=648, Percent_Identity=33.0246913580247, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=36.7579908675799, Blast_Score=259, Evalue=4e-69,
Organism=Saccharomyces cerevisiae, GI6323840, Length=674, Percent_Identity=38.8724035608309, Blast_Score=443, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6325016, Length=678, Percent_Identity=38.4955752212389, Blast_Score=441, Evalue=1e-124,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=37.956204379562, Blast_Score=460, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=681, Percent_Identity=36.417033773862, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24586016, Length=642, Percent_Identity=34.7352024922118, Blast_Score=358, Evalue=5e-99,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71095; Mature: 71095

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFEN
CCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKSTRGTEITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEE
LKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHH
IGEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VKRVFIMDEATQFLPRYLRFIKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSML
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYV
HHHHCCCHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHCCCCCCCHHCCCHHHHH
SRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFTGKKL
HHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVAD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
EQDMGLEMQRILQAAGQQIPVSKPIFEINPEHALIKRLHDIQDDNQFELWVTMLFEQAVL
CCCCCHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEGGQLDNPADFVNRVNRLLVSS
HCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSKQQTMGFQTEVKQMLHLVVHSLYSNKEIFLRELISNASDALDKLRFLALSNGSLFEN
CCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DSDLKISIQINEKLQTITISDNGIGLSWEEAVENLGTIAKSGTKEFISQLTGEQAKDSQL
CCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKSRRAGLQPEDGIVWESKGDGEFTIGYEKKSTRGTEITLH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEE
LKPENDEFLSDWRIRGIISKYSDHICWPIVMKKLSEEGKESKEFETVNKATALWTLQKSE
ECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEHHH
IGEEDYKQLYKHISHDYMDPLTWSHNHVEGKHEYITLLYIPAHAPFDLWQHEAKHGLKLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VKRVFIMDEATQFLPRYLRFIKGIVDASDLPLNISREILQDNKQVESIRAACTKRVLSML
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
EKMATNDKETYQKFWNEFGLVLKEGPIEDFANKEAIAKLLRFSTTASGSEKQEVSLEEYV
HHHHCCCHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHCCCCCCCHHCCCHHHHH
SRMKEGQDKIYYITASSYNAAKNSPHLEIFRKKGIEVLLLSDKVDEWLVGYMNEFTGKKL
HHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHH
QSISKGKVELGDDETSEQIKEQEKTLEPLIKHIKSVLNERVKDVLLTNRLTDSPACVVAD
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
EQDMGLEMQRILQAAGQQIPVSKPIFEINPEHALIKRLHDIQDDNQFELWVTMLFEQAVL
CCCCCHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AEGGQLDNPADFVNRVNRLLVSS
HCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA