Click here to switch to the map view.

The map label for this gene is xseA [H]

Identifier: 54293801

GI number: 54293801

Start: 972669

End: 974000

Strand: Reverse

Name: xseA [H]

Synonym: lpl0857

Alternate gene names: 54293801

Gene position: 974000-972669 (Counterclockwise)

Preceding gene: 54293807

Following gene: 54293800

Centisome position: 29.11

GC content: 40.09

Gene sequence:

>1332_bases
ATGAGTAGTCAATTGCCAATACTGACCGTGAGCCAGCTAAATAGACAAGTGAAAGGTTTTCTCGAGAATGAAATAGGCCT
TGTGCATGTCGAAGGCGAAATCTCTAACTTAAGCAAACCTTCTTCAGGACATTACTATTTCACCCTTAAAGACAGCACAG
CGCAAATTCGTTGCGCCTTTTTTAAAAATCGACATTCCAGTTCTCTGCTTAGAAATTTTAATGATGGTCAACAAATTGTT
GCCAGTGGCAAATTAAGTCTGTATGAAGCTCGGGGAGAATATCAGCTTATTGTTGAAGAGATAGTTGAAGCAGGAATGGG
GATTCTCTATCAACGATTTGAAGAGTTAAAAATCAAACTGGCCAGAGAAGGCTTATTCAATCCTGAGAGAAAAAAAACAC
TGCCCAGAATACCAGAAACGATTGGCATCATTACATCACCTACCGGAGCAGCTATCCAGGACATTCTCTCGACTCTGGCC
CGTCGATTCCCAATAGCGAGAATTATTATTTATCCAAGTGAGGTTCAAGGGCAAGCCGCCCCTCAACAACTAGTCAATGC
CTTAAAACTGGCTAATACCCATAAACGATGCCAGGTTCTCATCCTGGCGCGCGGCGGTGGCAGCATTGAAGACTTGTGGG
CTTTTAATGATGAATACCTTGCTCGACAAATTGCAATCAGCGAAATTCCTGTTGTTTCTGGTATTGGTCATGAAACAGAT
TTCACAATTGCTGATTTTGTAGCAGATTATCGCGCTGAAACGCCTACTGCTGCCGCTACGGCTGTTACTCCAAACTGCAT
CGAATTATTCAATATTCTTGATACGGCTATTTATCGATTGCATGATGCCATCATCAGACTGGTTAAAGGGTTGCAATTAA
AGCTCAATCATTTGATAGATAAAATTGCCTCACCCAGGCAAACTATCTCAACATACTGGCAAACCCTGGATTATCTGGAG
AGACAGTTAATATCTGCTATGACTCAATTTATTAACTTAAACATTAACAAGATGAATCTTTTTTCAACACGATTGCAAGC
TAACAATCCAAAAACACAAATTGAACGAACTAAAATCCAACTACGACAATTAATATTGCAATTAACCCAAGAGATCCGGA
TAAAAGTAAACCAATTAAAACATCAACTATCCACCAATCTTTCCACTTTACATGCTGTAAGCCCCTTGGCTACACTAGAT
AGAGGTTATGCTATTGTGAGTAAAAACCAAAGAATACTCTTTGCTGCCCAACAGGCACAAATTGGAGATACTATCGATGT
CCGTTTAGCAAAAGGAAGTCTTGCTTGTGAGGTTACTCAAATTAAGGATTGA

Upstream 100 bases:

>100_bases
ATAACCTTAAATGAAATAACATCTCACTACAATATAATTTTATTTCTTTAATTAGTTATTGTTGTTAACAACCTTTTGAT
TTGATGAGATTTTTACCACC

Downstream 100 bases:

>100_bases
CTAAAATCATGAAGAAACTATTACATTCACTTGCCTGTCTATTGATATTAATAAGCTCTGCAAAATTATCCTATGGCCTG
GCTCTACCAGAAAATCATTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSSSLLRNFNDGQQIV
ASGKLSLYEARGEYQLIVEEIVEAGMGILYQRFEELKIKLAREGLFNPERKKTLPRIPETIGIITSPTGAAIQDILSTLA
RRFPIARIIIYPSEVQGQAAPQQLVNALKLANTHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLE
RQLISAMTQFINLNINKMNLFSTRLQANNPKTQIERTKIQLRQLILQLTQEIRIKVNQLKHQLSTNLSTLHAVSPLATLD
RGYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD

Sequences:

>Translated_443_residues
MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSSSLLRNFNDGQQIV
ASGKLSLYEARGEYQLIVEEIVEAGMGILYQRFEELKIKLAREGLFNPERKKTLPRIPETIGIITSPTGAAIQDILSTLA
RRFPIARIIIYPSEVQGQAAPQQLVNALKLANTHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLE
RQLISAMTQFINLNINKMNLFSTRLQANNPKTQIERTKIQLRQLILQLTQEIRIKVNQLKHQLSTNLSTLHAVSPLATLD
RGYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD
>Mature_442_residues
SSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSSSLLRNFNDGQQIVA
SGKLSLYEARGEYQLIVEEIVEAGMGILYQRFEELKIKLAREGLFNPERKKTLPRIPETIGIITSPTGAAIQDILSTLAR
RFPIARIIIYPSEVQGQAAPQQLVNALKLANTHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETDF
TIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLER
QLISAMTQFINLNINKMNLFSTRLQANNPKTQIERTKIQLRQLILQLTQEIRIKVNQLKHQLSTNLSTLHAVSPLATLDR
GYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=446, Percent_Identity=41.9282511210762, Blast_Score=347, Evalue=8e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49655; Mature: 49524

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAF
CCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEEEEECCCCEEEEEE
FKNRHSSSLLRNFNDGQQIVASGKLSLYEARGEYQLIVEEIVEAGMGILYQRFEELKIKL
HHCCCHHHHHHCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREGLFNPERKKTLPRIPETIGIITSPTGAAIQDILSTLARRFPIARIIIYPSEVQGQAA
HHHCCCCCHHHCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
PQQLVNALKLANTHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCC
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLID
CHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIASPRQTISTYWQTLDYLERQLISAMTQFINLNINKMNLFSTRLQANNPKTQIERTKIQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCHHHHHHHHHH
LRQLILQLTQEIRIKVNQLKHQLSTNLSTLHAVSPLATLDRGYAIVSKNQRILFAAQQAQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHCCCEEEEECCCEEEEEECCCC
IGDTIDVRLAKGSLACEVTQIKD
CCCCEEEEEECCCEEEEEEECCC
>Mature Secondary Structure 
SSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAF
CCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEEEEECCCCEEEEEE
FKNRHSSSLLRNFNDGQQIVASGKLSLYEARGEYQLIVEEIVEAGMGILYQRFEELKIKL
HHCCCHHHHHHCCCCCHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AREGLFNPERKKTLPRIPETIGIITSPTGAAIQDILSTLARRFPIARIIIYPSEVQGQAA
HHHCCCCCHHHCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
PQQLVNALKLANTHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCC
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLID
CHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIASPRQTISTYWQTLDYLERQLISAMTQFINLNINKMNLFSTRLQANNPKTQIERTKIQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCHHHHHHHHHH
LRQLILQLTQEIRIKVNQLKHQLSTNLSTLHAVSPLATLDRGYAIVSKNQRILFAAQQAQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHCCCEEEEECCCEEEEEECCCC
IGDTIDVRLAKGSLACEVTQIKD
CCCCEEEEEECCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA