| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is purB [H]
Identifier: 54293778
GI number: 54293778
Start: 945559
End: 946929
Strand: Reverse
Name: purB [H]
Synonym: lpl0834
Alternate gene names: 54293778
Gene position: 946929-945559 (Counterclockwise)
Preceding gene: 54293780
Following gene: 54293777
Centisome position: 28.3
GC content: 38.66
Gene sequence:
>1371_bases ATGACACTTACTGCATTAAACGCGATTTCACCCATAGATGGTCGTTATGTCAATAAAACCAGAGCATTAAGTCCCTATTT TAGTGAGTTTGCATTAACCTATTATCGTTTAATGGTTGAAATCAAGTGGTTTGAATCATTAGCTGCTAACGACACTATTC CAGAAGTCCCTGCTTTAGATAACAAGGCTCGTAAATTTTTATCTGATCTTATTTCCAATTTTAATGAATCAGAAGCTGAA AAAATAAAAGAATTTGAAAAACAAACCAATCATGACGTTAAAGCCGTAGAGTATTATCTTAAGGATAAATTTCAGGAAAA TGAACAACTCAAATCTTGCGTTGCTTTCATACACTTTGCCTGCACTTCAGAGGACATCAATAACCTGGCTTATGCTTTAA TGATCAAACAAGCGATAGCCCAAGTTATACAACCTACTATAGCTGAGATCATGGGAAGCATTACGCTTCTTGGGAAACAA CATGCTGACGTTGCGATGCTCTCAAGAACGCATGGTCAACCAGCAACACCAACCACCATGGGTAAAGAATTGGTCAATTT TGTAGCTCGCCTTAAACGACCCCAGCAACAATTGGCAGAAGTATTAATCCCTGCCAAATTTAATGGAGCTGTTGGCAATT ACAATGCTCACGTAGCAGCCTATCCCGAAGTGGACTGGCGTAAGCATTGCGCTAATTTTGTTACATCCCTGGGTTTATCC TTTAACGCCTATACCACTCAAATTGAACCACATGATGGCATAGCGGAAGTCTCACAGATTATGGTGAGAATTAATAATAT TCTTCTGGATTATACCCAAGACATATGGAGCTATATTTCTCTTGGCTACTTTAAGCAAAAAACAATTGCCGAAGAAGTAG GCTCATCGACCATGCCGCACAAGGTAAATCCTATAGACTTTGAAAATGCCGAAGGCAATTTAGGTCTGTCTAATGCTTTA TTTATTCATTTTGCCAATAAATTAACTCAATCACGCATGCAAAGAGACCTGTCTGATTCGACTGTCTTACGTAACTTGGG CGTAGCCTTCTCTTACAGTTTGATTGCCTATCACTCAGTAGCCAAAGGTAATGACAAATTACAAATCAATAAATCAGCTC TACAAAAAGATTTATCCGAAAACTGGGAAGTTTTAGCAGAGGCCATACAAACTGTCATGCGCCGCTACAATGAACCCAAT GCCTATGAACAATTAAAAGAGCTTACACGAGGACAAATGATAGACGCTGAAAACCTTAAACAATTTATTAAAACCCTGTC TATTCCCGAAGAAGCAAAATCAGAATTAATGAAATTAACTCCAGAGACTTACACCGGTCTTGCGACCCAATTGGTCAAGG CTTTTTCATGA
Upstream 100 bases:
>100_bases CAAATTTACGCTAATTTTCTAGAATATTTATCGCTTTAATTCACATCTTGTCCTGCATCTAATATTATATACGCTTTAAT ATTGGAATAAGCTACCTATC
Downstream 100 bases:
>100_bases GTGATCAGCTATCACAACAAGGCCAATCGTTCGAATTCGATGTTCTCGTCATTGGGACAGGGTTAGCAGGGTTACATTAT TGTCTGCAGCTTTTAGCTAT
Product: adenylosuccinate lyase
Products: NA
Alternate protein names: ASL; Adenylosuccinase; ASase [H]
Number of amino acids: Translated: 456; Mature: 455
Protein sequence:
>456_residues MTLTALNAISPIDGRYVNKTRALSPYFSEFALTYYRLMVEIKWFESLAANDTIPEVPALDNKARKFLSDLISNFNESEAE KIKEFEKQTNHDVKAVEYYLKDKFQENEQLKSCVAFIHFACTSEDINNLAYALMIKQAIAQVIQPTIAEIMGSITLLGKQ HADVAMLSRTHGQPATPTTMGKELVNFVARLKRPQQQLAEVLIPAKFNGAVGNYNAHVAAYPEVDWRKHCANFVTSLGLS FNAYTTQIEPHDGIAEVSQIMVRINNILLDYTQDIWSYISLGYFKQKTIAEEVGSSTMPHKVNPIDFENAEGNLGLSNAL FIHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSVAKGNDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPN AYEQLKELTRGQMIDAENLKQFIKTLSIPEEAKSELMKLTPETYTGLATQLVKAFS
Sequences:
>Translated_456_residues MTLTALNAISPIDGRYVNKTRALSPYFSEFALTYYRLMVEIKWFESLAANDTIPEVPALDNKARKFLSDLISNFNESEAE KIKEFEKQTNHDVKAVEYYLKDKFQENEQLKSCVAFIHFACTSEDINNLAYALMIKQAIAQVIQPTIAEIMGSITLLGKQ HADVAMLSRTHGQPATPTTMGKELVNFVARLKRPQQQLAEVLIPAKFNGAVGNYNAHVAAYPEVDWRKHCANFVTSLGLS FNAYTTQIEPHDGIAEVSQIMVRINNILLDYTQDIWSYISLGYFKQKTIAEEVGSSTMPHKVNPIDFENAEGNLGLSNAL FIHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSVAKGNDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPN AYEQLKELTRGQMIDAENLKQFIKTLSIPEEAKSELMKLTPETYTGLATQLVKAFS >Mature_455_residues TLTALNAISPIDGRYVNKTRALSPYFSEFALTYYRLMVEIKWFESLAANDTIPEVPALDNKARKFLSDLISNFNESEAEK IKEFEKQTNHDVKAVEYYLKDKFQENEQLKSCVAFIHFACTSEDINNLAYALMIKQAIAQVIQPTIAEIMGSITLLGKQH ADVAMLSRTHGQPATPTTMGKELVNFVARLKRPQQQLAEVLIPAKFNGAVGNYNAHVAAYPEVDWRKHCANFVTSLGLSF NAYTTQIEPHDGIAEVSQIMVRINNILLDYTQDIWSYISLGYFKQKTIAEEVGSSTMPHKVNPIDFENAEGNLGLSNALF IHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSVAKGNDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPNA YEQLKELTRGQMIDAENLKQFIKTLSIPEEAKSELMKLTPETYTGLATQLVKAFS
Specific function: De novo purine biosynthesis; eighth step. [C]
COG id: COG0015
COG function: function code F; Adenylosuccinate lyase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily [H]
Homologues:
Organism=Escherichia coli, GI1787376, Length=452, Percent_Identity=56.858407079646, Blast_Score=542, Evalue=1e-155,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013539 - InterPro: IPR000362 - InterPro: IPR020557 - InterPro: IPR008948 - InterPro: IPR022761 - InterPro: IPR004769 [H]
Pfam domain/function: PF08328 ASL_C; PF00206 Lyase_1 [H]
EC number: =4.3.2.2 [H]
Molecular weight: Translated: 51419; Mature: 51288
Theoretical pI: Translated: 6.36; Mature: 6.36
Prosite motif: PS00163 FUMARATE_LYASES
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTLTALNAISPIDGRYVNKTRALSPYFSEFALTYYRLMVEIKWFESLAANDTIPEVPALD CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC NKARKFLSDLISNFNESEAEKIKEFEKQTNHDVKAVEYYLKDKFQENEQLKSCVAFIHFA HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH CTSEDINNLAYALMIKQAIAQVIQPTIAEIMGSITLLGKQHADVAMLSRTHGQPATPTTM HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHH GKELVNFVARLKRPQQQLAEVLIPAKFNGAVGNYNAHVAAYPEVDWRKHCANFVTSLGLS HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC FNAYTTQIEPHDGIAEVSQIMVRINNILLDYTQDIWSYISLGYFKQKTIAEEVGSSTMPH CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC KVNPIDFENAEGNLGLSNALFIHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSV CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH AKGNDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPNAYEQLKELTRGQMIDAENLK HCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH QFIKTLSIPEEAKSELMKLTPETYTGLATQLVKAFS HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCC >Mature Secondary Structure TLTALNAISPIDGRYVNKTRALSPYFSEFALTYYRLMVEIKWFESLAANDTIPEVPALD CCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC NKARKFLSDLISNFNESEAEKIKEFEKQTNHDVKAVEYYLKDKFQENEQLKSCVAFIHFA HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH CTSEDINNLAYALMIKQAIAQVIQPTIAEIMGSITLLGKQHADVAMLSRTHGQPATPTTM HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHH GKELVNFVARLKRPQQQLAEVLIPAKFNGAVGNYNAHVAAYPEVDWRKHCANFVTSLGLS HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC FNAYTTQIEPHDGIAEVSQIMVRINNILLDYTQDIWSYISLGYFKQKTIAEEVGSSTMPH CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC KVNPIDFENAEGNLGLSNALFIHFANKLTQSRMQRDLSDSTVLRNLGVAFSYSLIAYHSV CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH AKGNDKLQINKSALQKDLSENWEVLAEAIQTVMRRYNEPNAYEQLKELTRGQMIDAENLK HCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH QFIKTLSIPEEAKSELMKLTPETYTGLATQLVKAFS HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA