Click here to switch to the map view.

The map label for this gene is napA [H]

Identifier: 54296827

GI number: 54296827

Start: 977187

End: 978626

Strand: Direct

Name: napA [H]

Synonym: lpp0868

Alternate gene names: 54296827

Gene position: 977187-978626 (Clockwise)

Preceding gene: 54296826

Following gene: 54296828

Centisome position: 27.89

GC content: 38.89

Gene sequence:

>1440_bases
ATGAGTAATTCAAAATGGTGGTTTCTTTTAGTCTGTTTCATTCCTGCTATTACTTTTGCATCTGAGGGGGGAGAGCATTC
AGATCCAGTCACCTCTGTTCTTCTGGGTGTCACTACTATTTTATTTTTAGCTATCATTGGTCGTTATTTAGCCAGACTTC
TTAATCAACCTGGCGTTCTTGGTGAATTACTGATAGGGATGATAGTTGGGAATCTCTCTTACTTTTTCGGAAGTGAATTA
GTAGTAATTCTTCGCGAAGGTTCTGCCATTTATGATGTTGTCAAAGAAATGTTAGCAGGAATTTCTTTAAATCAGGCGGT
AACTCATGTTATCCATAATTCCTATTATGCTAACCAGGTGATCCATGCCTTAAGTGGAGCAGAGGGAACTGAATATCTTA
AAATAGCCTATGTCGTTGATATTTTCTCACGTTATGGTGTCATATTTCTTCTTTTTATGGTTGGTCTTGAGACGTCACTT
TCTGATTTGAAAAAAACTGGCAAAGAATCCATTCTTGTTGCTGTGATCGGTATCGTTGCGCCAATGATTTTAGGGTTTGT
AGTGGCTTGTTTTATCATACCTAACTCAAATTACAAGATTAATTTATTTATCGGCGCTACCTTGAGTGCTACCAGCATTG
GTATTACAGCAAGTGTTCTTAAAGAGATGAATAAACTGAGTACACGGGAAGCAAGAACAATTCTTGGTGCGGCTACTTTG
GATGATATTTTAGGCCTGATTATTTTGGCGGTAGTCAGCAGTATAGTTATCAGTGGTGCTGTAAGCATCATGGTTGTAAT
GAAAATTATCATTTTAGCTCTACTGTTTTTCATTGGTACCTTGTTTATGGGGCCTTTTGTACTTCGGAAAGCAGTCGATT
TATTCCGTTTTCTGGAGCCTTGGGAATCCAAATTATTTATCTCATTCCTTTTTATTATGGCATTAGCCTGGTTGGCTTCA
TTTATACAGTTGGCGGCTATAATTGGTGCTTTTGCTGCGGGTGTCATTTTGCACGACGACTATTTTGGAGAGCAAAAAGC
CCATCATAAAGATCATCGCAGTATTCATCATTTGGTATCTCCCTTGGAAACTATATTGGCTCCTATGTTTTTTACTCTCA
TTGGGATACAGGTTAAGTTAGAAACTTTTTATGATTGGAATGTCATTGTTTTAGCGGGAGGCTTATCAGTAGCGGCCATT
CTTGGCAAGCTGCTTAGTGGCTTAGGCGCTAATCGACGGGATGATAGGCTGCTCATTGGTATAGGAATGTTGCCTCGTGG
AGAGGTAGGATTGGTTTTTGCTTCTATTGGCAGAACTATAGGCGTAATAAGTGATAATCTGTTTACCGCAATTGTATTGA
TGATCATGATCACAACCTTTATTGCGCCACCTTTATTAAAGATGCGATATGCCAAACCAAAAGAGGATAGGAATGCATGA

Upstream 100 bases:

>100_bases
CTGTTAGTAATGGAACTACTTGTGATGGTATGGTGTTGCAATTCAAAATTCCCTTGCATTTGGGAGAAAGCAGCATATTA
AGCTTATAGGATAAAGCGGT

Downstream 100 bases:

>100_bases
ATAATGTTTTATCGCAAGTTACATTTGATGTAAAACGTGCTTTGCAAGAGGACGTGGGCAATGGTGATGTTACTGCGGCT
TTGTTGCCTCAGCAGCTGAT

Product: hypothetical protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSNSKWWFLLVCFIPAITFASEGGEHSDPVTSVLLGVTTILFLAIIGRYLARLLNQPGVLGELLIGMIVGNLSYFFGSEL
VVILREGSAIYDVVKEMLAGISLNQAVTHVIHNSYYANQVIHALSGAEGTEYLKIAYVVDIFSRYGVIFLLFMVGLETSL
SDLKKTGKESILVAVIGIVAPMILGFVVACFIIPNSNYKINLFIGATLSATSIGITASVLKEMNKLSTREARTILGAATL
DDILGLIILAVVSSIVISGAVSIMVVMKIIILALLFFIGTLFMGPFVLRKAVDLFRFLEPWESKLFISFLFIMALAWLAS
FIQLAAIIGAFAAGVILHDDYFGEQKAHHKDHRSIHHLVSPLETILAPMFFTLIGIQVKLETFYDWNVIVLAGGLSVAAI
LGKLLSGLGANRRDDRLLIGIGMLPRGEVGLVFASIGRTIGVISDNLFTAIVLMIMITTFIAPPLLKMRYAKPKEDRNA

Sequences:

>Translated_479_residues
MSNSKWWFLLVCFIPAITFASEGGEHSDPVTSVLLGVTTILFLAIIGRYLARLLNQPGVLGELLIGMIVGNLSYFFGSEL
VVILREGSAIYDVVKEMLAGISLNQAVTHVIHNSYYANQVIHALSGAEGTEYLKIAYVVDIFSRYGVIFLLFMVGLETSL
SDLKKTGKESILVAVIGIVAPMILGFVVACFIIPNSNYKINLFIGATLSATSIGITASVLKEMNKLSTREARTILGAATL
DDILGLIILAVVSSIVISGAVSIMVVMKIIILALLFFIGTLFMGPFVLRKAVDLFRFLEPWESKLFISFLFIMALAWLAS
FIQLAAIIGAFAAGVILHDDYFGEQKAHHKDHRSIHHLVSPLETILAPMFFTLIGIQVKLETFYDWNVIVLAGGLSVAAI
LGKLLSGLGANRRDDRLLIGIGMLPRGEVGLVFASIGRTIGVISDNLFTAIVLMIMITTFIAPPLLKMRYAKPKEDRNA
>Mature_478_residues
SNSKWWFLLVCFIPAITFASEGGEHSDPVTSVLLGVTTILFLAIIGRYLARLLNQPGVLGELLIGMIVGNLSYFFGSELV
VILREGSAIYDVVKEMLAGISLNQAVTHVIHNSYYANQVIHALSGAEGTEYLKIAYVVDIFSRYGVIFLLFMVGLETSLS
DLKKTGKESILVAVIGIVAPMILGFVVACFIIPNSNYKINLFIGATLSATSIGITASVLKEMNKLSTREARTILGAATLD
DILGLIILAVVSSIVISGAVSIMVVMKIIILALLFFIGTLFMGPFVLRKAVDLFRFLEPWESKLFISFLFIMALAWLASF
IQLAAIIGAFAAGVILHDDYFGEQKAHHKDHRSIHHLVSPLETILAPMFFTLIGIQVKLETFYDWNVIVLAGGLSVAAIL
GKLLSGLGANRRDDRLLIGIGMLPRGEVGLVFASIGRTIGVISDNLFTAIVLMIMITTFIAPPLLKMRYAKPKEDRNA

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=410, Percent_Identity=25.1219512195122, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 52144; Mature: 52013

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSKWWFLLVCFIPAITFASEGGEHSDPVTSVLLGVTTILFLAIIGRYLARLLNQPGVL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GELLIGMIVGNLSYFFGSELVVILREGSAIYDVVKEMLAGISLNQAVTHVIHNSYYANQV
HHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IHALSGAEGTEYLKIAYVVDIFSRYGVIFLLFMVGLETSLSDLKKTGKESILVAVIGIVA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
PMILGFVVACFIIPNSNYKINLFIGATLSATSIGITASVLKEMNKLSTREARTILGAATL
HHHHHHHHHHHHCCCCCEEEEEEEECEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDILGLIILAVVSSIVISGAVSIMVVMKIIILALLFFIGTLFMGPFVLRKAVDLFRFLEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WESKLFISFLFIMALAWLASFIQLAAIIGAFAAGVILHDDYFGEQKAHHKDHRSIHHLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
PLETILAPMFFTLIGIQVKLETFYDWNVIVLAGGLSVAAILGKLLSGLGANRRDDRLLIG
HHHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEE
IGMLPRGEVGLVFASIGRTIGVISDNLFTAIVLMIMITTFIAPPLLKMRYAKPKEDRNA
ECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNSKWWFLLVCFIPAITFASEGGEHSDPVTSVLLGVTTILFLAIIGRYLARLLNQPGVL
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GELLIGMIVGNLSYFFGSELVVILREGSAIYDVVKEMLAGISLNQAVTHVIHNSYYANQV
HHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IHALSGAEGTEYLKIAYVVDIFSRYGVIFLLFMVGLETSLSDLKKTGKESILVAVIGIVA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
PMILGFVVACFIIPNSNYKINLFIGATLSATSIGITASVLKEMNKLSTREARTILGAATL
HHHHHHHHHHHHCCCCCEEEEEEEECEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDILGLIILAVVSSIVISGAVSIMVVMKIIILALLFFIGTLFMGPFVLRKAVDLFRFLEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WESKLFISFLFIMALAWLASFIQLAAIIGAFAAGVILHDDYFGEQKAHHKDHRSIHHLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
PLETILAPMFFTLIGIQVKLETFYDWNVIVLAGGLSVAAILGKLLSGLGANRRDDRLLIG
HHHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEE
IGMLPRGEVGLVFASIGRTIGVISDNLFTAIVLMIMITTFIAPPLLKMRYAKPKEDRNA
ECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]