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The map label for this gene is mutT3 [H]

Identifier: 54027315

GI number: 54027315

Start: 5645664

End: 5646392

Strand: Reverse

Name: mutT3 [H]

Synonym: nfa53410

Alternate gene names: 54027315

Gene position: 5646392-5645664 (Counterclockwise)

Preceding gene: 54027319

Following gene: 54027313

Centisome position: 93.77

GC content: 75.03

Gene sequence:

>729_bases
GTGATGCGTGGTGACGGTGACGGGTGGTCGGAGGGCCCGGACGGGCTACGGCACTGGGGCAAGTACGGCGCTGCCGGGTT
GTTGCTGCGGGCGCCGTTGGCGGGCGGCGGCTCGGCGGTGCTGTTGCAGCATCGGGCGCCGTGGAGCCACCAGGGCGGCA
CCTGGGCGCTGCCGGGTGGCGCCAAGGACAGCCACGAGTCCTCCGTGCACGCCGCCGTGCGCGAGGCGTGGGAGGAAGCG
GGCATCGACCCCACCGCCGTGCGAGTGCGCGCCGAACGGGTGACCGCGTCGGCGTTGAGCGGCTGGACCTACACCACCGT
CGTCGCCGACACCGACCAGACCCTGCGCACCAGCCGCGACCGGGAGAGCCTCGAACTGGCGTGGGTCCCCGAGGACGAGG
TCACCGACCGCCCCCTGCACCCCGGCTTCGCCGCCGCCTGGCCCGCCCTGCGCGCCACCCCTGCTCGCGCCTGCCTGAGC
GAGCTGGACGACGCCGACACCGTGGCCGCGGCCCTGCCCCGCACCGTCGACCTCGCCGACCAGGGCTTCCTCTGGTTGCA
CTCCGACCCCGACGGACCCGGCGGCTACGCCCGCATCGTCGCCGACACTGCCGACACTGCCGACACTGCCGACTCCGCCG
ACACTGCCGAGTCCGGCGGTGCGCCGGAGGGGCAGTCGGGCGCGCTGGTGCGCACGGTGTCGCTCACGGTGCGGCAGATC
CTCGCCTGA

Upstream 100 bases:

>100_bases
GCGTCGCAGTTTATTGTGGTCCTACCGATGCCGCGGTGCGTCGATCACCCCGGGGCGGGTGCGACGGGGGAACGCCGCCG
CGGCGCAACGAGGATGGTTT

Downstream 100 bases:

>100_bases
GCACAGCGTGCCGCCGCCTCCGGCCGCCGACCTGCTCAGGAGGCTGTGCTGAATTTCGCCTGAGCGGGGCGGCCTGCGTG
GTGATGCTGCGCTGCCGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MMRGDGDGWSEGPDGLRHWGKYGAAGLLLRAPLAGGGSAVLLQHRAPWSHQGGTWALPGGAKDSHESSVHAAVREAWEEA
GIDPTAVRVRAERVTASALSGWTYTTVVADTDQTLRTSRDRESLELAWVPEDEVTDRPLHPGFAAAWPALRATPARACLS
ELDDADTVAAALPRTVDLADQGFLWLHSDPDGPGGYARIVADTADTADTADSADTAESGGAPEGQSGALVRTVSLTVRQI
LA

Sequences:

>Translated_242_residues
MMRGDGDGWSEGPDGLRHWGKYGAAGLLLRAPLAGGGSAVLLQHRAPWSHQGGTWALPGGAKDSHESSVHAAVREAWEEA
GIDPTAVRVRAERVTASALSGWTYTTVVADTDQTLRTSRDRESLELAWVPEDEVTDRPLHPGFAAAWPALRATPARACLS
ELDDADTVAAALPRTVDLADQGFLWLHSDPDGPGGYARIVADTADTADTADSADTAESGGAPEGQSGALVRTVSLTVRQI
LA
>Mature_242_residues
MMRGDGDGWSEGPDGLRHWGKYGAAGLLLRAPLAGGGSAVLLQHRAPWSHQGGTWALPGGAKDSHESSVHAAVREAWEEA
GIDPTAVRVRAERVTASALSGWTYTTVVADTDQTLRTSRDRESLELAWVPEDEVTDRPLHPGFAAAWPALRATPARACLS
ELDDADTVAAALPRTVDLADQGFLWLHSDPDGPGGYARIVADTADTADTADSADTAESGGAPEGQSGALVRTVSLTVRQI
LA

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equa

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 25379; Mature: 25379

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRGDGDGWSEGPDGLRHWGKYGAAGLLLRAPLAGGGSAVLLQHRAPWSHQGGTWALPGG
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEECCCC
AKDSHESSVHAAVREAWEEAGIDPTAVRVRAERVTASALSGWTYTTVVADTDQTLRTSRD
CCCCHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHHHCCCEEEEEEECCCHHHHHCCC
RESLELAWVPEDEVTDRPLHPGFAAAWPALRATPARACLSELDDADTVAAALPRTVDLAD
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCEEECC
QGFLWLHSDPDGPGGYARIVADTADTADTADSADTAESGGAPEGQSGALVRTVSLTVRQI
CCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCCCCCCEEEHHHHHHHHH
LA
HC
>Mature Secondary Structure
MMRGDGDGWSEGPDGLRHWGKYGAAGLLLRAPLAGGGSAVLLQHRAPWSHQGGTWALPGG
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEECCCC
AKDSHESSVHAAVREAWEEAGIDPTAVRVRAERVTASALSGWTYTTVVADTDQTLRTSRD
CCCCHHHHHHHHHHHHHHHHCCCHHHEEEEHHHHHHHHHCCCEEEEEEECCCHHHHHCCC
RESLELAWVPEDEVTDRPLHPGFAAAWPALRATPARACLSELDDADTVAAALPRTVDLAD
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCHHHHHHHCCCCEEECC
QGFLWLHSDPDGPGGYARIVADTADTADTADSADTAESGGAPEGQSGALVRTVSLTVRQI
CCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHCCCCCCCCCCCEEEHHHHHHHHH
LA
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]