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The map label for this gene is fadE44 [H]

Identifier: 54027302

GI number: 54027302

Start: 5630017

End: 5631177

Strand: Reverse

Name: fadE44 [H]

Synonym: nfa53280

Alternate gene names: 54027302

Gene position: 5631177-5630017 (Counterclockwise)

Preceding gene: 54027303

Following gene: 54027301

Centisome position: 93.52

GC content: 67.87

Gene sequence:

>1161_bases
ATGAGCTTCATCGAGAGCGACGAGCGCAAGCAGCTGCGGGCCGCGGTGGCCGCGCTGGCCGCCAAGTACACCTATCGCGA
CTACGTGCTGCCCAAGGCCCGCAAGAACGAGCCCCTCACCGAGTTGTGGGACGAGGCAGGGAAATTGGGCTTCCTCGGGG
TGAACCTGCCCGAGGAGTACGGCGGCGGCGGTGCGGGCATGTACGAGCTGGCACTGGTGATGGAGGAACTGTCCGCCCAA
GGCGCGGGCCTGCTGCTCATGGTGGTCTCCCCGGCCATCTGCGGCACCATCATCAGCCGCTACGGCACCGACGAGCAGAA
GCAGCAGTGGCTGCCCAAGCTCTCCGACGGCTCGGCCAAGATGGTCTTCGGCATCACCGAACCCGACGCCGGGTCCAACT
CCCACCAGATCACCACCACGGCCCGCCGTGACGGCGACGACTGGCTGCTGACCGGCCGCAAGATCTTCATCTCCGGCGTG
GACCAGGCCGAGGCGGTGCTGATCGTCGCGCGTACCGAGGACCACAAGACCGGCAAGCTCAAGCCCGCCCTGTTCATCGT
GCCCACCGACGCCCCCGGCTTCACCAAGGTGGCGCAGGAGATGGACATCATCGAGCCCGACCACCAGTTCAGCCTGTTCC
TCGACGACGTGCGCCTGCCCTCCAGCGCACTGGTCGGCCGGGAGGACGCCGCGCTGATGCAGCTGTTCGCCGGGCTGAAT
CCCGAGCGGATCATGGGTGCGGCGATGGCCGTCGGCGTGGCCCGCTACGCCATCGACCGTGCCGTCGAATACGCCAAGGA
GCGCACGGTGTGGAAGACGCCGATCGGTGCGCACCAAGGCATTTCGCATCCGTTGGCGCAGGTGAAGATCGAGCTGGAGA
TGGCCAAGCTGATGATGCAGAAGGCCGCCACCCTCTACGACGCGGGCGACGAGATGGGTGCGGCGGAAGCCGCCAACATG
GCCAAGTACGCCGCCGCCGAGGTCAGCATCAAGGCGCTCGACCAGGCCATCCAGACCCACGGCGGCGCGGGCCTGACCGC
CGACTACGGGCTGGCCGCGATGCTCGGCGCCGCCCGCATCGCGCGGATCGCGCCGGTGAGCCGGGAGATGGTGCTGAACT
TCGTGTCCCAGCACTCGCTCGGCCTGCCCAAGTCGTACTGA

Upstream 100 bases:

>100_bases
GCTCAGCGCGGTGAACGTCGCGGTCGGCCAGCAGGTCGACATCGGCACGGTATTGGCCGTCGTGGAACCCGCGGCCGACG
ACACAGAGAAGGACTGAGCC

Downstream 100 bases:

>100_bases
TCCGCGCCGTACCGATCCGCCGGAAGGGGAGCACGATGACCGACACCTCCACCGCGCCGCTGGTGCGCTACGACGTCCGC
GACCGCTTCGCCGTGCTGAC

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSFIESDERKQLRAAVAALAAKYTYRDYVLPKARKNEPLTELWDEAGKLGFLGVNLPEEYGGGGAGMYELALVMEELSAQ
GAGLLLMVVSPAICGTIISRYGTDEQKQQWLPKLSDGSAKMVFGITEPDAGSNSHQITTTARRDGDDWLLTGRKIFISGV
DQAEAVLIVARTEDHKTGKLKPALFIVPTDAPGFTKVAQEMDIIEPDHQFSLFLDDVRLPSSALVGREDAALMQLFAGLN
PERIMGAAMAVGVARYAIDRAVEYAKERTVWKTPIGAHQGISHPLAQVKIELEMAKLMMQKAATLYDAGDEMGAAEAANM
AKYAAAEVSIKALDQAIQTHGGAGLTADYGLAAMLGAARIARIAPVSREMVLNFVSQHSLGLPKSY

Sequences:

>Translated_386_residues
MSFIESDERKQLRAAVAALAAKYTYRDYVLPKARKNEPLTELWDEAGKLGFLGVNLPEEYGGGGAGMYELALVMEELSAQ
GAGLLLMVVSPAICGTIISRYGTDEQKQQWLPKLSDGSAKMVFGITEPDAGSNSHQITTTARRDGDDWLLTGRKIFISGV
DQAEAVLIVARTEDHKTGKLKPALFIVPTDAPGFTKVAQEMDIIEPDHQFSLFLDDVRLPSSALVGREDAALMQLFAGLN
PERIMGAAMAVGVARYAIDRAVEYAKERTVWKTPIGAHQGISHPLAQVKIELEMAKLMMQKAATLYDAGDEMGAAEAANM
AKYAAAEVSIKALDQAIQTHGGAGLTADYGLAAMLGAARIARIAPVSREMVLNFVSQHSLGLPKSY
>Mature_385_residues
SFIESDERKQLRAAVAALAAKYTYRDYVLPKARKNEPLTELWDEAGKLGFLGVNLPEEYGGGGAGMYELALVMEELSAQG
AGLLLMVVSPAICGTIISRYGTDEQKQQWLPKLSDGSAKMVFGITEPDAGSNSHQITTTARRDGDDWLLTGRKIFISGVD
QAEAVLIVARTEDHKTGKLKPALFIVPTDAPGFTKVAQEMDIIEPDHQFSLFLDDVRLPSSALVGREDAALMQLFAGLNP
ERIMGAAMAVGVARYAIDRAVEYAKERTVWKTPIGAHQGISHPLAQVKIELEMAKLMMQKAATLYDAGDEMGAAEAANMA
KYAAAEVSIKALDQAIQTHGGAGLTADYGLAAMLGAARIARIAPVSREMVLNFVSQHSLGLPKSY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=362, Percent_Identity=29.2817679558011, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI4557233, Length=343, Percent_Identity=32.3615160349854, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4501859, Length=361, Percent_Identity=29.6398891966759, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=28.8, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI4557231, Length=370, Percent_Identity=26.7567567567568, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI187960098, Length=370, Percent_Identity=26.7567567567568, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226958414, Length=338, Percent_Identity=28.4023668639053, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI38505218, Length=277, Percent_Identity=31.0469314079422, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI7656849, Length=362, Percent_Identity=24.8618784530387, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI48976061, Length=324, Percent_Identity=26.2345679012346, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI211971008, Length=324, Percent_Identity=26.2345679012346, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI76496475, Length=345, Percent_Identity=28.4057971014493, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4557235, Length=345, Percent_Identity=28.4057971014493, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI21361497, Length=347, Percent_Identity=26.5129682997118, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4503943, Length=339, Percent_Identity=25.9587020648968, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI7669494, Length=339, Percent_Identity=25.9587020648968, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=26.509186351706, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786223, Length=370, Percent_Identity=27.5675675675676, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081702, Length=332, Percent_Identity=25, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=370, Percent_Identity=31.6216216216216, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=389, Percent_Identity=28.5347043701799, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=28.9189189189189, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=29.6969696969697, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17508101, Length=330, Percent_Identity=27.8787878787879, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=28, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71990804, Length=279, Percent_Identity=32.9749103942652, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17533517, Length=338, Percent_Identity=26.3313609467456, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=335, Percent_Identity=26.5671641791045, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=335, Percent_Identity=25.9701492537313, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=219, Percent_Identity=31.5068493150685, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=27.7620396600567, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71982178, Length=238, Percent_Identity=30.2521008403361, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=282, Percent_Identity=28.0141843971631, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=284, Percent_Identity=27.112676056338, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=339, Percent_Identity=25.3687315634218, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24660351, Length=369, Percent_Identity=28.4552845528455, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21355753, Length=333, Percent_Identity=29.7297297297297, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI21356377, Length=329, Percent_Identity=30.3951367781155, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24666513, Length=364, Percent_Identity=30.2197802197802, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=29.0575916230367, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI281363737, Length=346, Percent_Identity=30.3468208092486, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19920834, Length=265, Percent_Identity=27.1698113207547, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41571; Mature: 41440

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIESDERKQLRAAVAALAAKYTYRDYVLPKARKNEPLTELWDEAGKLGFLGVNLPEEY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCCCHHH
GGGGAGMYELALVMEELSAQGAGLLLMVVSPAICGTIISRYGTDEQKQQWLPKLSDGSAK
CCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCE
MVFGITEPDAGSNSHQITTTARRDGDDWLLTGRKIFISGVDQAEAVLIVARTEDHKTGKL
EEEEECCCCCCCCCCEEEEECCCCCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCC
KPALFIVPTDAPGFTKVAQEMDIIEPDHQFSLFLDDVRLPSSALVGREDAALMQLFAGLN
CCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHCCC
PERIMGAAMAVGVARYAIDRAVEYAKERTVWKTPIGAHQGISHPLAQVKIELEMAKLMMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KAATLYDAGDEMGAAEAANMAKYAAAEVSIKALDQAIQTHGGAGLTADYGLAAMLGAARI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ARIAPVSREMVLNFVSQHSLGLPKSY
HHHCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SFIESDERKQLRAAVAALAAKYTYRDYVLPKARKNEPLTELWDEAGKLGFLGVNLPEEY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCCCHHH
GGGGAGMYELALVMEELSAQGAGLLLMVVSPAICGTIISRYGTDEQKQQWLPKLSDGSAK
CCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCE
MVFGITEPDAGSNSHQITTTARRDGDDWLLTGRKIFISGVDQAEAVLIVARTEDHKTGKL
EEEEECCCCCCCCCCEEEEECCCCCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCC
KPALFIVPTDAPGFTKVAQEMDIIEPDHQFSLFLDDVRLPSSALVGREDAALMQLFAGLN
CCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHCCCCHHHHHHHHHCCC
PERIMGAAMAVGVARYAIDRAVEYAKERTVWKTPIGAHQGISHPLAQVKIELEMAKLMMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KAATLYDAGDEMGAAEAANMAKYAAAEVSIKALDQAIQTHGGAGLTADYGLAAMLGAARI
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ARIAPVSREMVLNFVSQHSLGLPKSY
HHHCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]