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The map label for this gene is sglT [H]

Identifier: 54026477

GI number: 54026477

Start: 4668612

End: 4670369

Strand: Reverse

Name: sglT [H]

Synonym: nfa45040

Alternate gene names: 54026477

Gene position: 4670369-4668612 (Counterclockwise)

Preceding gene: 54026478

Following gene: 54026476

Centisome position: 77.57

GC content: 66.1

Gene sequence:

>1758_bases
GTGCCGCTTGCCGATTCCCTGTTCCTGACCTCCGCCGCACCCGGATCGCCCGCCGCCGCGGTGCGTTTCGAGGCGGTCGA
GACGCTGCGCCTGGACGCCGATCCGGTCGACTACGCGCTGGTCGCGTTGTATTTCGTGTTCGTGCTCGGTATCGGATTGC
TGGCGCGCAGCCGGGTCTCCTCCAGCATCGACTTCTTCCTGTCCGGCCGGTCGCTGCCAGCCTGGGTGACCGGCCTGGCC
TTCATCTCGGCCAACCTCGGCGCGGTCGAGATCATGGGCATGTCGGCCAACGGCGCCGAATACGGATTCCCCACCTTCCA
CTATTTCTGGATCGGCGCGATTCCGGCCATGCTGTTCCTCGGCGTGGTGATGATGCCGTTCTATTACGGCTCCAAGGTGC
GCAGCGTGCCGGAGTTCATGCGCAGGCGCTTCGGCACCGGCGCGCACCTGGTGAACGCGCTCAGCTTCGCCACCGCGCAG
ATCCTCATCGCCGGGGTCAACCTGTACCTGCTCGGCTCGATCCTCAATGTGCTGCTCGGCTGGCCGCTGTGGGTCTCGGT
GGTCGCCGCCGCGGCGATCGTGCTGTCCTACATCACCCTCGGCGGGCTCTCGGCCGCCATCTACAACGAAGTTCTGCAGT
TCTTCGTCATCGTCGCGGCACTGCTGCCGTTGACCCTCGTCGGCCTGCACCGGGTGGGCGGCTGGGACGGGCTGACCGAA
CGGGTCACCGCCTCGCCGGGTGGCGCCGCCCAGCTGGATTCGTGGCCGGGCAACGCGCTCAGCGGGTTCACCGACAACTT
CCTGTCGGTGCTCGGCATCGTCTTCGGTCTCGGCTTCGTGCTGTCCTTCGGTTACTGGACCACCAACTTCGTCGAGGTCC
AGCGCGCGATGGCGACCAACTCGATCTCCGCGGCCCGGCGCACGCCCATCATCGGCGCCTACCCGAAGATGTTCATCCCG
CTCATCGTGGTCATCCCCGGCATGATCAGCGCTGTGCTCGTGCCGGAGATGATCGAGTACAAGCAGGCCAAGGCGGCCGA
TCCGGATTTCAGCGGCGATGTCACCTACAACCAGGCCCTGCTGTACCTGATGAAGGAGGTCCTGCCGAACGGTCTGCTCG
GGGTGGGCCTGGCCGGTCTGCTCGCGGCGTTCATGGCGGGCATGGCCGCCAACGTCTCGGCCTTCAACACCGTGTTCAGC
TTCGACCTCTGGCAGCAGTACGTGGTGAAGGACCGGCCCGACGGCTATTACCTCACCGTCGGCAGGCTGGCCACGGTCGG
GGCGACGGTCGCGGCCATCTTCACCGCGTTCATCGCGGGCAATTTCAGCAACATGATGGACTACCTGCAGACGCTGTTCA
GCTTCTTCAACGCGCCGCTGTTCGCGACGTTCATCCTCGGCATGTTCTGGAAGCGGATGACCCCGACCGCGGGCTGGGCG
GGCCTGGTGGCCGGAACCGGTTCGGCCATCGTCATCTTCCTGCTGCACGAGATGGAGGTCTTCCAACTGTCCGGCCAGGG
TGCCAGTTTCGTCGCCGCCGGCGTTGCCTTCGTGGTCGACATCCTGGTCAGCGTCGCGGTGACGATGGTGACCCAGCCCA
AGCCGGCCGCCGAACTGGTGGGGCTGGTGTACTCCGAGACACCCGCACAGCTGCGCACCGACCCCGAGGCGGCCACGCTG
CCCTGGTATCAGCGCCCCGTGCTGCTCGCGGGCATCGCCCTGGTGCTGGTCATTCTGCTCAACATCTTCGTGGGATAG

Upstream 100 bases:

>100_bases
GGACGCCGCAGGTCGGTGCGGGGTCGCTGTCGCCGCACGAAGCCGCTCGCCGCGCGCGACCCGCTCGTCGAGTGGTGCCA
CCGCAAGGAGGGACACCGCT

Downstream 100 bases:

>100_bases
GGAGATCCGATGCTGTTCGACATCCGCACCATCGTGGCCGCGCTGCTCGGCAGTTACGGGATCATCCTGGTGATCACCGG
GCTGGTCCACGACACCGCCG

Product: putative transporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MPLADSLFLTSAAPGSPAAAVRFEAVETLRLDADPVDYALVALYFVFVLGIGLLARSRVSSSIDFFLSGRSLPAWVTGLA
FISANLGAVEIMGMSANGAEYGFPTFHYFWIGAIPAMLFLGVVMMPFYYGSKVRSVPEFMRRRFGTGAHLVNALSFATAQ
ILIAGVNLYLLGSILNVLLGWPLWVSVVAAAAIVLSYITLGGLSAAIYNEVLQFFVIVAALLPLTLVGLHRVGGWDGLTE
RVTASPGGAAQLDSWPGNALSGFTDNFLSVLGIVFGLGFVLSFGYWTTNFVEVQRAMATNSISAARRTPIIGAYPKMFIP
LIVVIPGMISAVLVPEMIEYKQAKAADPDFSGDVTYNQALLYLMKEVLPNGLLGVGLAGLLAAFMAGMAANVSAFNTVFS
FDLWQQYVVKDRPDGYYLTVGRLATVGATVAAIFTAFIAGNFSNMMDYLQTLFSFFNAPLFATFILGMFWKRMTPTAGWA
GLVAGTGSAIVIFLLHEMEVFQLSGQGASFVAAGVAFVVDILVSVAVTMVTQPKPAAELVGLVYSETPAQLRTDPEAATL
PWYQRPVLLAGIALVLVILLNIFVG

Sequences:

>Translated_585_residues
MPLADSLFLTSAAPGSPAAAVRFEAVETLRLDADPVDYALVALYFVFVLGIGLLARSRVSSSIDFFLSGRSLPAWVTGLA
FISANLGAVEIMGMSANGAEYGFPTFHYFWIGAIPAMLFLGVVMMPFYYGSKVRSVPEFMRRRFGTGAHLVNALSFATAQ
ILIAGVNLYLLGSILNVLLGWPLWVSVVAAAAIVLSYITLGGLSAAIYNEVLQFFVIVAALLPLTLVGLHRVGGWDGLTE
RVTASPGGAAQLDSWPGNALSGFTDNFLSVLGIVFGLGFVLSFGYWTTNFVEVQRAMATNSISAARRTPIIGAYPKMFIP
LIVVIPGMISAVLVPEMIEYKQAKAADPDFSGDVTYNQALLYLMKEVLPNGLLGVGLAGLLAAFMAGMAANVSAFNTVFS
FDLWQQYVVKDRPDGYYLTVGRLATVGATVAAIFTAFIAGNFSNMMDYLQTLFSFFNAPLFATFILGMFWKRMTPTAGWA
GLVAGTGSAIVIFLLHEMEVFQLSGQGASFVAAGVAFVVDILVSVAVTMVTQPKPAAELVGLVYSETPAQLRTDPEAATL
PWYQRPVLLAGIALVLVILLNIFVG
>Mature_584_residues
PLADSLFLTSAAPGSPAAAVRFEAVETLRLDADPVDYALVALYFVFVLGIGLLARSRVSSSIDFFLSGRSLPAWVTGLAF
ISANLGAVEIMGMSANGAEYGFPTFHYFWIGAIPAMLFLGVVMMPFYYGSKVRSVPEFMRRRFGTGAHLVNALSFATAQI
LIAGVNLYLLGSILNVLLGWPLWVSVVAAAAIVLSYITLGGLSAAIYNEVLQFFVIVAALLPLTLVGLHRVGGWDGLTER
VTASPGGAAQLDSWPGNALSGFTDNFLSVLGIVFGLGFVLSFGYWTTNFVEVQRAMATNSISAARRTPIIGAYPKMFIPL
IVVIPGMISAVLVPEMIEYKQAKAADPDFSGDVTYNQALLYLMKEVLPNGLLGVGLAGLLAAFMAGMAANVSAFNTVFSF
DLWQQYVVKDRPDGYYLTVGRLATVGATVAAIFTAFIAGNFSNMMDYLQTLFSFFNAPLFATFILGMFWKRMTPTAGWAG
LVAGTGSAIVIFLLHEMEVFQLSGQGASFVAAGVAFVVDILVSVAVTMVTQPKPAAELVGLVYSETPAQLRTDPEAATLP
WYQRPVLLAGIALVLVILLNIFVG

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI17941285, Length=461, Percent_Identity=28.8503253796095, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI14140236, Length=557, Percent_Identity=25.3141831238779, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI4507031, Length=579, Percent_Identity=26.5975820379965, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4507033, Length=561, Percent_Identity=28.1639928698752, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI206597483, Length=600, Percent_Identity=27.3333333333333, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI110835708, Length=552, Percent_Identity=27.7173913043478, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI206597487, Length=624, Percent_Identity=26.2820512820513, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI109659836, Length=472, Percent_Identity=27.7542372881356, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI109659839, Length=483, Percent_Identity=26.9151138716356, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI4507035, Length=460, Percent_Identity=25.2173913043478, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI157671931, Length=469, Percent_Identity=22.6012793176972, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI256985183, Length=435, Percent_Identity=24.5977011494253, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI167466278, Length=470, Percent_Identity=24.468085106383, Blast_Score=83, Evalue=8e-16,
Organism=Escherichia coli, GI1790113, Length=459, Percent_Identity=23.9651416122004, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566512, Length=389, Percent_Identity=23.1362467866324, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641117, Length=464, Percent_Identity=23.0603448275862, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573698, Length=459, Percent_Identity=20.9150326797386, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651739, Length=448, Percent_Identity=20.9821428571429, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24651741, Length=475, Percent_Identity=18.7368421052632, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362054, Length=403, Percent_Identity=24.8138957816377, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281362052, Length=403, Percent_Identity=24.8138957816377, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281362050, Length=403, Percent_Identity=24.8138957816377, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648056, Length=403, Percent_Identity=24.8138957816377, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356827, Length=403, Percent_Identity=24.8138957816377, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24645928, Length=463, Percent_Identity=22.6781857451404, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650192, Length=361, Percent_Identity=22.9916897506925, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362918, Length=459, Percent_Identity=19.8257080610022, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 62475; Mature: 62344

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLADSLFLTSAAPGSPAAAVRFEAVETLRLDADPVDYALVALYFVFVLGIGLLARSRVS
CCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SSIDFFLSGRSLPAWVTGLAFISANLGAVEIMGMSANGAEYGFPTFHYFWIGAIPAMLFL
CCHHHEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
GVVMMPFYYGSKVRSVPEFMRRRFGTGAHLVNALSFATAQILIAGVNLYLLGSILNVLLG
HHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPLWVSVVAAAAIVLSYITLGGLSAAIYNEVLQFFVIVAALLPLTLVGLHRVGGWDGLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RVTASPGGAAQLDSWPGNALSGFTDNFLSVLGIVFGLGFVLSFGYWTTNFVEVQRAMATN
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
SISAARRTPIIGAYPKMFIPLIVVIPGMISAVLVPEMIEYKQAKAADPDFSGDVTYNQAL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
LYLMKEVLPNGLLGVGLAGLLAAFMAGMAANVSAFNTVFSFDLWQQYVVKDRPDGYYLTV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
GRLATVGATVAAIFTAFIAGNFSNMMDYLQTLFSFFNAPLFATFILGMFWKRMTPTAGWA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCH
GLVAGTGSAIVIFLLHEMEVFQLSGQGASFVAAGVAFVVDILVSVAVTMVTQPKPAAELV
HHHHCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GLVYSETPAQLRTDPEAATLPWYQRPVLLAGIALVLVILLNIFVG
HHHHCCCCHHHCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLADSLFLTSAAPGSPAAAVRFEAVETLRLDADPVDYALVALYFVFVLGIGLLARSRVS
CCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHCCCCHHHCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]