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The map label for this gene is gpsA

Identifier: 54026177

GI number: 54026177

Start: 4355565

End: 4356575

Strand: Reverse

Name: gpsA

Synonym: nfa42060

Alternate gene names: 54026177

Gene position: 4356575-4355565 (Counterclockwise)

Preceding gene: 54026181

Following gene: 54026176

Centisome position: 72.35

GC content: 71.02

Gene sequence:

>1011_bases
ATGACGAGGGCGGCAGTACTTGGTGCGGGTTCCTGGGGAACCGCGTTCGCGAAGGTGTTGGCCGACGCGGGAACAGAGGT
GACGATCTGGGCGCGGCGCCCGGAGATCGCCGAGGCGTTGGCCACCGAACACCGCAATCCCGCCTACCTTCCGGACGTGC
AACTACCCGCCGTATCGGCCACGCACGACGCCGAGGCCGCGCTCGACGGCGCGCAACTGGTCGTGCTCGCGGTGCCCTCG
CAGTCGCTGCGGGCCAACCTCACCGGATGGCGGCCCGCGCTGCGCGCCGCCATCGACGAGCACGACGCCACACTGCTGAG
TCTGGCGAAGGGCATCGAGACCGGCACGCTGCTGCGGATGAGTCAGGTCATCGCGGAGGTGACCGGCGCCGAGGAACGCC
GCATCGCGGTGCTCTCCGGTCCGAACCTGGCCAGGGAGATCGCGGCCGGACAGCCCGCCGCGACCGTCATCGCCTGTTCC
GACGCCGCCCGGGCGGAGGCCGTGCAACAGGCCAGCTACACCGGCTATTTCCGCCCGTACACCAACACCGACGTGATCGG
CTGCGAGATCGGCGGCGCCTGCAAGAACGTGATCGCGCTGGCCTGCGGCATCGCGGCGGGCATGGGTCTGGGTGACAACT
CCATCGCCAGCCTCATCACCCGCGGCCTCGCCGAGATCATGCGGCTGGCGGTGACCCTCGGCGCGGAGCCGGTGACGCTG
GCCGGGCTGGCCGGGGTCGGCGACCTGGTCGCCACCTGCACCTCGCCGCTGTCGCGCAATCGTTCCTTCGGGCATGTGCT
CGGCGCGGGCGGATCGATGGAGGCGGCGCAGCAGGCGACCCATGGACAGGTCGCCGAGGGTGTGAAGTCGTGCACATCGG
TGCGGGCGCTGGCCGCCGCGCACGAGGTGGAGATGCCGTTGACCGACGCCGTGCACCGGGTGTGCCACGAGGGCATTTCG
GTTCGCGAGGCCGTCGGCAGCCTGCTCGGACGCCGCATCAAGCCGGAGTAG

Upstream 100 bases:

>100_bases
GGCGAGACGGCTCTTGGCCTGATCCAGGCGCTTGACCGCGATCAGGGCGTGCACGGCGTGCGGACGCATGCGCCCAATCC
TTGCATGGCATATTGGGTTG

Downstream 100 bases:

>100_bases
GGACCCCAGAAGTCCGGGCACGGGCAGCGACGGAGAAGCCCGCCGCGCCCGGTACCGTTCGGTGCATGACGAACCGGATC
AGGGTGGCTGTGGTGTTCGG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTRAAVLGAGSWGTAFAKVLADAGTEVTIWARRPEIAEALATEHRNPAYLPDVQLPAVSATHDAEAALDGAQLVVLAVPS
QSLRANLTGWRPALRAAIDEHDATLLSLAKGIETGTLLRMSQVIAEVTGAEERRIAVLSGPNLAREIAAGQPAATVIACS
DAARAEAVQQASYTGYFRPYTNTDVIGCEIGGACKNVIALACGIAAGMGLGDNSIASLITRGLAEIMRLAVTLGAEPVTL
AGLAGVGDLVATCTSPLSRNRSFGHVLGAGGSMEAAQQATHGQVAEGVKSCTSVRALAAAHEVEMPLTDAVHRVCHEGIS
VREAVGSLLGRRIKPE

Sequences:

>Translated_336_residues
MTRAAVLGAGSWGTAFAKVLADAGTEVTIWARRPEIAEALATEHRNPAYLPDVQLPAVSATHDAEAALDGAQLVVLAVPS
QSLRANLTGWRPALRAAIDEHDATLLSLAKGIETGTLLRMSQVIAEVTGAEERRIAVLSGPNLAREIAAGQPAATVIACS
DAARAEAVQQASYTGYFRPYTNTDVIGCEIGGACKNVIALACGIAAGMGLGDNSIASLITRGLAEIMRLAVTLGAEPVTL
AGLAGVGDLVATCTSPLSRNRSFGHVLGAGGSMEAAQQATHGQVAEGVKSCTSVRALAAAHEVEMPLTDAVHRVCHEGIS
VREAVGSLLGRRIKPE
>Mature_335_residues
TRAAVLGAGSWGTAFAKVLADAGTEVTIWARRPEIAEALATEHRNPAYLPDVQLPAVSATHDAEAALDGAQLVVLAVPSQ
SLRANLTGWRPALRAAIDEHDATLLSLAKGIETGTLLRMSQVIAEVTGAEERRIAVLSGPNLAREIAAGQPAATVIACSD
AARAEAVQQASYTGYFRPYTNTDVIGCEIGGACKNVIALACGIAAGMGLGDNSIASLITRGLAEIMRLAVTLGAEPVTLA
GLAGVGDLVATCTSPLSRNRSFGHVLGAGGSMEAAQQATHGQVAEGVKSCTSVRALAAAHEVEMPLTDAVHRVCHEGISV
REAVGSLLGRRIKPE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=348, Percent_Identity=31.6091954022989, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24307999, Length=351, Percent_Identity=27.6353276353276, Blast_Score=115, Evalue=5e-26,
Organism=Escherichia coli, GI1790037, Length=335, Percent_Identity=43.2835820895522, Blast_Score=241, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI32564399, Length=340, Percent_Identity=29.1176470588235, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17507425, Length=337, Percent_Identity=29.3768545994065, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193210136, Length=349, Percent_Identity=28.3667621776504, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32564403, Length=349, Percent_Identity=28.3667621776504, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193210134, Length=333, Percent_Identity=25.2252252252252, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324513, Length=356, Percent_Identity=28.6516853932584, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320181, Length=352, Percent_Identity=29.8295454545455, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17136202, Length=354, Percent_Identity=27.4011299435028, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI17136204, Length=354, Percent_Identity=27.4011299435028, Blast_Score=111, Evalue=9e-25,
Organism=Drosophila melanogaster, GI17136200, Length=354, Percent_Identity=27.4011299435028, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI22026922, Length=360, Percent_Identity=24.7222222222222, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45551945, Length=335, Percent_Identity=26.865671641791, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281362270, Length=297, Percent_Identity=26.9360269360269, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24648969, Length=295, Percent_Identity=27.4576271186441, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_NOCFA (Q5YRY6)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_120419.1
- ProteinModelPortal:   Q5YRY6
- SMR:   Q5YRY6
- GeneID:   3108756
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa42060
- NMPDR:   fig|247156.1.peg.4055
- HOGENOM:   HBG586392
- OMA:   SQTLRGN
- ProtClustDB:   PRK00094
- BioCyc:   NFAR247156:NFA42060-MONOMER
- BRENDA:   1.1.1.94
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34507; Mature: 34376

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 195-195 BINDING 110-110 BINDING 110-110 BINDING 144-144 BINDING 259-259 BINDING 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAAVLGAGSWGTAFAKVLADAGTEVTIWARRPEIAEALATEHRNPAYLPDVQLPAVSA
CCCCEEEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCC
THDAEAALDGAQLVVLAVPSQSLRANLTGWRPALRAAIDEHDATLLSLAKGIETGTLLRM
CCCHHHHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SQVIAEVTGAEERRIAVLSGPNLAREIAAGQPAATVIACSDAARAEAVQQASYTGYFRPY
HHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCEECCC
TNTDVIGCEIGGACKNVIALACGIAAGMGLGDNSIASLITRGLAEIMRLAVTLGAEPVTL
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEH
AGLAGVGDLVATCTSPLSRNRSFGHVLGAGGSMEAAQQATHGQVAEGVKSCTSVRALAAA
HHHHHHHHHHHHHCCHHHCCCCCCCEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHH
HEVEMPLTDAVHRVCHEGISVREAVGSLLGRRIKPE
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TRAAVLGAGSWGTAFAKVLADAGTEVTIWARRPEIAEALATEHRNPAYLPDVQLPAVSA
CCCEEEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCC
THDAEAALDGAQLVVLAVPSQSLRANLTGWRPALRAAIDEHDATLLSLAKGIETGTLLRM
CCCHHHHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SQVIAEVTGAEERRIAVLSGPNLAREIAAGQPAATVIACSDAARAEAVQQASYTGYFRPY
HHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCEECCC
TNTDVIGCEIGGACKNVIALACGIAAGMGLGDNSIASLITRGLAEIMRLAVTLGAEPVTL
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEH
AGLAGVGDLVATCTSPLSRNRSFGHVLGAGGSMEAAQQATHGQVAEGVKSCTSVRALAAA
HHHHHHHHHHHHHCCHHHCCCCCCCEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHH
HEVEMPLTDAVHRVCHEGISVREAVGSLLGRRIKPE
HHCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA