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The map label for this gene is hup [H]

Identifier: 54026181

GI number: 54026181

Start: 4360616

End: 4361314

Strand: Reverse

Name: hup [H]

Synonym: nfa42100

Alternate gene names: 54026181

Gene position: 4361314-4360616 (Counterclockwise)

Preceding gene: 54026182

Following gene: 54026177

Centisome position: 72.43

GC content: 67.53

Gene sequence:

>699_bases
ATGAACAAGGCGGAACTGATCGACGTTCTGACCGAAAAGTTGGGTACGGACAGGCGCACGGCTACCGCGGCAGTCGAGCA
TGTTGTCGACACCATCGTGCGTGCAGTGCACAAGGGCCAGAGCGTCACCATCACCGGATTCGGTGTCTTCGAACAGCGCA
AGCGTGCCCCCCGTGTCGCCCGGAACCCGCGCACCGGCGAAACCGTCAAGGTGAAAGCCACTTCGGTGCCCGCGTTCCGG
CCCGGCGCCCAATTCAAGGCGGTGATCGCGGGTAAGCAGAAGCTGGCCGCGACCGGCCCGGCCGTCAAGCGGGGCGTGAA
TGCCCCTGTGGCGGCCAAGAAGACGGCGGCCAAGAAGACCACGGCCGCCGCCAAGAAGACCGCCGCCAAGAAGACCACCA
CGGCCACCAAGGCCCCCGCCAAGAAGACGACGGCGACCAAGGCCCCGGCGAAGTCGACCGCACGGAAGACCACCACGGCC
ACCAAGACCGCCGCCAAGAAGGCACCCGCGAAGAAGACGACGGCCACCAAGGCTTCGGCGACCAAGGCGTCGGCGACCAA
GGCCACCGCGGCCAAGAAGACCACCACCGCCGCCAAGAAGACCACGGCGACGAAGGCCACGGCCGCCAAGAAGACCACGG
CCGCGAAGAAGGCGCCCGCGAAGAAGACCGCGGCCAAGAAGACCGCCGCCCGCCGCTGA

Upstream 100 bases:

>100_bases
CACCATGAATTTTGGCGTGGCACATAGACTCTTGCCCAAAGTGGGTTTACCGTGGTACCTAGTCGGTCCGACGACGGGCC
ATTAGTCTGCGGAGGATTCA

Downstream 100 bases:

>100_bases
AGCGGCCCACCCACACCCCGCCGCTGGACCGAGAACGGCCCCGGGACATCTCCCGGGGCCGTTTCGGCTTGTGGGGATCG
GGTTTTCGATCATGGGGGAA

Product: putative histone-like DNA-binding protein

Products: NA

Alternate protein names: Histone-like protein; Hlp [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKAELIDVLTEKLGTDRRTATAAVEHVVDTIVRAVHKGQSVTITGFGVFEQRKRAPRVARNPRTGETVKVKATSVPAFR
PGAQFKAVIAGKQKLAATGPAVKRGVNAPVAAKKTAAKKTTAAAKKTAAKKTTTATKAPAKKTTATKAPAKSTARKTTTA
TKTAAKKAPAKKTTATKASATKASATKATAAKKTTTAAKKTTATKATAAKKTTAAKKAPAKKTAAKKTAARR

Sequences:

>Translated_232_residues
MNKAELIDVLTEKLGTDRRTATAAVEHVVDTIVRAVHKGQSVTITGFGVFEQRKRAPRVARNPRTGETVKVKATSVPAFR
PGAQFKAVIAGKQKLAATGPAVKRGVNAPVAAKKTAAKKTTAAAKKTAAKKTTTATKAPAKKTTATKAPAKSTARKTTTA
TKTAAKKAPAKKTTATKASATKASATKATAAKKTTTAAKKTTATKATAAKKTTAAKKAPAKKTAAKKTAARR
>Mature_232_residues
MNKAELIDVLTEKLGTDRRTATAAVEHVVDTIVRAVHKGQSVTITGFGVFEQRKRAPRVARNPRTGETVKVKATSVPAFR
PGAQFKAVIAGKQKLAATGPAVKRGVNAPVAAKKTAAKKTTAAAKKTAAKKTTTATKAPAKKTTATKAPAKSTARKTTTA
TKTAAKKAPAKKTTATKASATKASATKATAAKKTTTAAKKTTATKATAAKKTTAAKKAPAKKTAAKKTAARR

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1788005, Length=87, Percent_Identity=40.2298850574713, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790433, Length=82, Percent_Identity=42.6829268292683, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787141, Length=87, Percent_Identity=35.632183908046, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786644, Length=82, Percent_Identity=34.1463414634146, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 23811; Mature: 23811

Theoretical pI: Translated: 12.34; Mature: 12.34

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELIDVLTEKLGTDRRTATAAVEHVVDTIVRAVHKGQSVTITGFGVFEQRKRAPRVA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCHHH
RNPRTGETVKVKATSVPAFRPGAQFKAVIAGKQKLAATGPAVKRGVNAPVAAKKTAAKKT
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCHHHHHCCHHHHHCCCCCCHHHHHHHHHH
TAAAKKTAAKKTTTATKAPAKKTTATKAPAKSTARKTTTATKTAAKKAPAKKTTATKASA
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TKASATKATAAKKTTTAAKKTTATKATAAKKTTAAKKAPAKKTAAKKTAARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNKAELIDVLTEKLGTDRRTATAAVEHVVDTIVRAVHKGQSVTITGFGVFEQRKRAPRVA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCHHH
RNPRTGETVKVKATSVPAFRPGAQFKAVIAGKQKLAATGPAVKRGVNAPVAAKKTAAKKT
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCHHHHHCCHHHHHCCCCCCHHHHHHHHHH
TAAAKKTAAKKTTTATKAPAKKTTATKAPAKSTARKTTTATKTAAKKAPAKKTTATKASA
HHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TKASATKATAAKKTTTAAKKTTATKATAAKKTTAAKKAPAKKTAAKKTAARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]