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The map label for this gene is ruvA

Identifier: 54025666

GI number: 54025666

Start: 3914268

End: 3914873

Strand: Reverse

Name: ruvA

Synonym: nfa36960

Alternate gene names: 54025666

Gene position: 3914873-3914268 (Counterclockwise)

Preceding gene: 54025667

Following gene: 54025665

Centisome position: 65.02

GC content: 73.27

Gene sequence:

>606_bases
GTGATCGCGTCGGTACGCGGCGAGGTGCTCGAGATCGCGCTGGACCACGTGGTGGTGGAGGCGGCGGGCGTCGGCTACCG
GCTCAACGCCACCCCGTCGACGCTGGCCACCCTCACCCGCGGCGCGGAAGCGCGGCTCTACACGGCGATGATCGTCCGCG
AGGACTCGATGACCCTGTACGGCTTCGCCGACACCGAGGCGCGCGACCTGTTCGGCCTGTTGCAGACCGTCTCCGGTGTC
GGGCCGCGCCTGGCGATGGCGGTGCTGGCCGTGCTCGAGCCCGAGGCGCTGCGCAAGGCCCTGGCCGAGAGCAACGTCGC
GGCGCTCACCCGGGTGCCCGGCATCGGCAAACGCGGCGCCGAACGCATGGTGGTGGAGCTGCGGGACAAGGTGAACCTGG
TGCCGGTGCAGGCGGGCCCGCCCGGCAGCACTCCCGCCGTCGCCGCCACCCCGGTGCGCGAGCAGGTGGTCGAAGCGCTC
ACCGGGCTCGGGTTCCCGCTCAAACAGGCCGAACAGGCGCTCGACACGGTGTTGGCCGAGCAGCCCGCCGCCGACACCTC
CACCGCGCTGCGCGCCGCGCTGTCGCTGCTGGGCAAGAACCGGTAG

Upstream 100 bases:

>100_bases
CGCCGCTGCTGGCCAGGATGGCCGCGGCCGAGGCCAAGGCGGCCGAGGCCAAGCGGCGCTACACCGAACGACTGGCCGAA
CAACGGAAGGCGGTGCGCGG

Downstream 100 bases:

>100_bases
GCCGCGATGGACGACCACGACGATTCCCCGGTCAGCCCGAGCTTCCTGAAGTCCGACGGCGAGATCGAGGCCAGCCTGCG
CCCGAAATCCCTGGACGACT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIASVRGEVLEIALDHVVVEAAGVGYRLNATPSTLATLTRGAEARLYTAMIVREDSMTLYGFADTEARDLFGLLQTVSGV
GPRLAMAVLAVLEPEALRKALAESNVAALTRVPGIGKRGAERMVVELRDKVNLVPVQAGPPGSTPAVAATPVREQVVEAL
TGLGFPLKQAEQALDTVLAEQPAADTSTALRAALSLLGKNR

Sequences:

>Translated_201_residues
MIASVRGEVLEIALDHVVVEAAGVGYRLNATPSTLATLTRGAEARLYTAMIVREDSMTLYGFADTEARDLFGLLQTVSGV
GPRLAMAVLAVLEPEALRKALAESNVAALTRVPGIGKRGAERMVVELRDKVNLVPVQAGPPGSTPAVAATPVREQVVEAL
TGLGFPLKQAEQALDTVLAEQPAADTSTALRAALSLLGKNR
>Mature_201_residues
MIASVRGEVLEIALDHVVVEAAGVGYRLNATPSTLATLTRGAEARLYTAMIVREDSMTLYGFADTEARDLFGLLQTVSGV
GPRLAMAVLAVLEPEALRKALAESNVAALTRVPGIGKRGAERMVVELRDKVNLVPVQAGPPGSTPAVAATPVREQVVEAL
TGLGFPLKQAEQALDTVLAEQPAADTSTALRAALSLLGKNR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=34.8258706467662, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_NOCFA (Q5YTE7)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_119908.1
- ProteinModelPortal:   Q5YTE7
- SMR:   Q5YTE7
- GeneID:   3111545
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa36960
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   NFAR247156:NFA36960-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21022; Mature: 21022

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASVRGEVLEIALDHVVVEAAGVGYRLNATPSTLATLTRGAEARLYTAMIVREDSMTLY
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHEEEECCCEEEE
GFADTEARDLFGLLQTVSGVGPRLAMAVLAVLEPEALRKALAESNVAALTRVPGIGKRGA
EECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHCCCCCCCCH
ERMVVELRDKVNLVPVQAGPPGSTPAVAATPVREQVVEALTGLGFPLKQAEQALDTVLAE
HHHHHHHHCCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
QPAADTSTALRAALSLLGKNR
CCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIASVRGEVLEIALDHVVVEAAGVGYRLNATPSTLATLTRGAEARLYTAMIVREDSMTLY
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCHHHHHHHEEEECCCEEEE
GFADTEARDLFGLLQTVSGVGPRLAMAVLAVLEPEALRKALAESNVAALTRVPGIGKRGA
EECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHCCCCCCCCH
ERMVVELRDKVNLVPVQAGPPGSTPAVAATPVREQVVEALTGLGFPLKQAEQALDTVLAE
HHHHHHHHCCCCEEEECCCCCCCCCCEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
QPAADTSTALRAALSLLGKNR
CCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA