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The map label for this gene is ruvC

Identifier: 54025667

GI number: 54025667

Start: 3914870

End: 3915439

Strand: Reverse

Name: ruvC

Synonym: nfa36970

Alternate gene names: 54025667

Gene position: 3915439-3914870 (Counterclockwise)

Preceding gene: 54025668

Following gene: 54025666

Centisome position: 65.03

GC content: 72.98

Gene sequence:

>570_bases
GTGCGGGTGATGGGCGTCGACCCCGGGCTCACCAGGTGCGGACTCAGCATGGTCGAGGGCGGGCACGGGCGCACCGTCAC
CGCACTGGACGTCGACGTGGTGCGCACCCCGGCGGACATGGACCTGGCGCATCGGCTGATGCTGGTCGCCGACGCCGCCG
AGTACTGGATGGACACCCACCGCCCGGGCGCGGTCGCCATCGAGCGCGTCTTCGCCCAGCACAACGTCCGCACGGCGATG
GGCACCGCGCAGGCGGGCGGGGTGATCGCGCTGGCCGCGGCCCGTCGCGACATCCCGGTGGTGTTCCACACCCCCAGCGA
GGTCAAGGCCGCCGTCACCGGCAACGGCAACGCGGACAAGGCGCAGGTGACCGCGATGGTCACCCGCATCCTCGGGTTGC
AGACCGCGCCGAAACCCGCCGACGCGGCGGATGCGCTGGCCCTGGCGATCTGTCATTGTTGGCGGGCGCCGCTGCTGGCC
AGGATGGCCGCGGCCGAGGCCAAGGCGGCCGAGGCCAAGCGGCGCTACACCGAACGACTGGCCGAACAACGGAAGGCGGT
GCGCGGGTGA

Upstream 100 bases:

>100_bases
CCGGAGCCGGCGCCGGAGAGTGACCGTGTCGCTGGTAGGGCGGGCCTGCCCCGTCCACTAGACTCTCGAACAGTTGTTCG
TGTCCGGGAGAGGGGTTTTC

Downstream 100 bases:

>100_bases
TCGCGTCGGTACGCGGCGAGGTGCTCGAGATCGCGCTGGACCACGTGGTGGTGGAGGCGGCGGGCGTCGGCTACCGGCTC
AACGCCACCCCGTCGACGCT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MRVMGVDPGLTRCGLSMVEGGHGRTVTALDVDVVRTPADMDLAHRLMLVADAAEYWMDTHRPGAVAIERVFAQHNVRTAM
GTAQAGGVIALAAARRDIPVVFHTPSEVKAAVTGNGNADKAQVTAMVTRILGLQTAPKPADAADALALAICHCWRAPLLA
RMAAAEAKAAEAKRRYTERLAEQRKAVRG

Sequences:

>Translated_189_residues
MRVMGVDPGLTRCGLSMVEGGHGRTVTALDVDVVRTPADMDLAHRLMLVADAAEYWMDTHRPGAVAIERVFAQHNVRTAM
GTAQAGGVIALAAARRDIPVVFHTPSEVKAAVTGNGNADKAQVTAMVTRILGLQTAPKPADAADALALAICHCWRAPLLA
RMAAAEAKAAEAKRRYTERLAEQRKAVRG
>Mature_189_residues
MRVMGVDPGLTRCGLSMVEGGHGRTVTALDVDVVRTPADMDLAHRLMLVADAAEYWMDTHRPGAVAIERVFAQHNVRTAM
GTAQAGGVIALAAARRDIPVVFHTPSEVKAAVTGNGNADKAQVTAMVTRILGLQTAPKPADAADALALAICHCWRAPLLA
RMAAAEAKAAEAKRRYTERLAEQRKAVRG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=136, Percent_Identity=33.8235294117647, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_NOCFA (Q5YTE6)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_119909.1
- ProteinModelPortal:   Q5YTE6
- SMR:   Q5YTE6
- GeneID:   3111547
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa36970
- HOGENOM:   HBG437552
- OMA:   RIAYQMT
- ProtClustDB:   PRK00039
- BioCyc:   NFAR247156:NFA36970-MONOMER
- BRENDA:   3.1.22.4
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 20056; Mature: 20056

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVMGVDPGLTRCGLSMVEGGHGRTVTALDVDVVRTPADMDLAHRLMLVADAAEYWMDTH
CEEECCCCCHHHHHHHHHCCCCCCEEEEEEHEECCCCCCHHHHHHHHHHHHHHHHHHHCC
RPGAVAIERVFAQHNVRTAMGTAQAGGVIALAAARRDIPVVFHTPSEVKAAVTGNGNADK
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCHHEEEEECCCCCCH
AQVTAMVTRILGLQTAPKPADAADALALAICHCWRAPLLARMAAAEAKAAEAKRRYTERL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQRKAVRG
HHHHHHCCC
>Mature Secondary Structure
MRVMGVDPGLTRCGLSMVEGGHGRTVTALDVDVVRTPADMDLAHRLMLVADAAEYWMDTH
CEEECCCCCHHHHHHHHHCCCCCCEEEEEEHEECCCCCCHHHHHHHHHHHHHHHHHHHCC
RPGAVAIERVFAQHNVRTAMGTAQAGGVIALAAARRDIPVVFHTPSEVKAAVTGNGNADK
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCHHEEEEECCCCCCH
AQVTAMVTRILGLQTAPKPADAADALALAICHCWRAPLLARMAAAEAKAAEAKRRYTERL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEQRKAVRG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA