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The map label for this gene is ruvB

Identifier: 54025665

GI number: 54025665

Start: 3913188

End: 3914261

Strand: Reverse

Name: ruvB

Synonym: nfa36950

Alternate gene names: 54025665

Gene position: 3914261-3913188 (Counterclockwise)

Preceding gene: 54025666

Following gene: 54025664

Centisome position: 65.01

GC content: 72.25

Gene sequence:

>1074_bases
ATGGACGACCACGACGATTCCCCGGTCAGCCCGAGCTTCCTGAAGTCCGACGGCGAGATCGAGGCCAGCCTGCGCCCGAA
ATCCCTGGACGACTTCATCGGGCAGCCGCGCGTGCGCGAACAACTGGCGCTGGTGCTGCGCGGGGCCAAACAGCGCGGCA
GCACGCCCGATCACGTGCTGCTGTCCGGGCCGCCCGGCCTCGGCAAGACCAGCATGGCGATGATCATCGCCGCCGAACTC
GGCACCGCCCTGCGCATCACCTCCGGCCCGGCCCTGGAGCGGGCGGGCGACCTCGCCGCCATGCTCAGCAACCTGGTCGA
GGGCGATGTGCTGTTCATCGACGAGATCCACCGCATCGCCCGGCCCGCCGAGGAGATGCTGTACCTGGCGATGGAGGACT
TCCGCGTCGACGTCGTGGTCGGCAAGGGCCCCGGTGCCACCTCGATCCCGCTCGACATCGCCCCGTTCACGCTGGTCGGG
GCGACCACCCGCTCCGGCGCGCTCACCGGGCCGCTGCGTGATCGCTTCGGCTTCACCGGGCACATGGACTTCTACGAGCC
CGGTGAACTGCTGCGCATCCTGGAACGCTCGGCCCAGATCCTCGGCGTGCGCATCGAGACCGACGCCGCCGCCGAGATCG
CCGGCCGCTCCCGGGGCACGCCGCGCATCGCCAACCGGCTGCTGCGCCGGGTCCGCGACTACGCCGAGGTGCGCGCCGAC
GGCATCGTCACACTGCCGGTCGCCCGGGCCGCGCTCGAGGTCTACGACGTGGACACCCTCGGCCTGGACCGCCTCGACCG
CGCGGTGCTCGACGCGCTGGTGCGCGGCTTCCACGGTGGCCCGGTCGGGGTGTCCACGCTGGCGGTGGCGGTGGGGGAGG
AGGCCACCACCGTCGAGGAGGTGTGCGAGCCCTTCCTGGTGCGCGCCGGGCTGGTGGCACGCACGCCTCGCGGCCGGGTG
GCGACCGCGGCGGCCTGGGAACACCTCGGTCTGGTCCCACCACCGGACCTGGTGTTCGGCTCGATCGAGGTGCGCGGGAG
GACATCCCAGCCCACCCTCGACCTGTTCGACTGA

Upstream 100 bases:

>100_bases
ACAGGCGCTCGACACGGTGTTGGCCGAGCAGCCCGCCGCCGACACCTCCACCGCGCTGCGCGCCGCGCTGTCGCTGCTGG
GCAAGAACCGGTAGGCCGCG

Downstream 100 bases:

>100_bases
CCCCCGCCGCGACGGCACCGGCCCGCGCGCCCGGATAGAGTCGGGACATGACGGTGGTCCAATCCGTGCTCGACCGAATG
CCCGAGCCGCTGCGCAGCAA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MDDHDDSPVSPSFLKSDGEIEASLRPKSLDDFIGQPRVREQLALVLRGAKQRGSTPDHVLLSGPPGLGKTSMAMIIAAEL
GTALRITSGPALERAGDLAAMLSNLVEGDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLDIAPFTLVG
ATTRSGALTGPLRDRFGFTGHMDFYEPGELLRILERSAQILGVRIETDAAAEIAGRSRGTPRIANRLLRRVRDYAEVRAD
GIVTLPVARAALEVYDVDTLGLDRLDRAVLDALVRGFHGGPVGVSTLAVAVGEEATTVEEVCEPFLVRAGLVARTPRGRV
ATAAAWEHLGLVPPPDLVFGSIEVRGRTSQPTLDLFD

Sequences:

>Translated_357_residues
MDDHDDSPVSPSFLKSDGEIEASLRPKSLDDFIGQPRVREQLALVLRGAKQRGSTPDHVLLSGPPGLGKTSMAMIIAAEL
GTALRITSGPALERAGDLAAMLSNLVEGDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLDIAPFTLVG
ATTRSGALTGPLRDRFGFTGHMDFYEPGELLRILERSAQILGVRIETDAAAEIAGRSRGTPRIANRLLRRVRDYAEVRAD
GIVTLPVARAALEVYDVDTLGLDRLDRAVLDALVRGFHGGPVGVSTLAVAVGEEATTVEEVCEPFLVRAGLVARTPRGRV
ATAAAWEHLGLVPPPDLVFGSIEVRGRTSQPTLDLFD
>Mature_357_residues
MDDHDDSPVSPSFLKSDGEIEASLRPKSLDDFIGQPRVREQLALVLRGAKQRGSTPDHVLLSGPPGLGKTSMAMIIAAEL
GTALRITSGPALERAGDLAAMLSNLVEGDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLDIAPFTLVG
ATTRSGALTGPLRDRFGFTGHMDFYEPGELLRILERSAQILGVRIETDAAAEIAGRSRGTPRIANRLLRRVRDYAEVRAD
GIVTLPVARAALEVYDVDTLGLDRLDRAVLDALVRGFHGGPVGVSTLAVAVGEEATTVEEVCEPFLVRAGLVARTPRGRV
ATAAAWEHLGLVPPPDLVFGSIEVRGRTSQPTLDLFD

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=312, Percent_Identity=54.8076923076923, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_NOCFA (Q5YTE8)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_119907.1
- ProteinModelPortal:   Q5YTE8
- SMR:   Q5YTE8
- GeneID:   3111546
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa36950
- NMPDR:   fig|247156.1.peg.3602
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   NFAR247156:NFA36950-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38220; Mature: 38220

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDHDDSPVSPSFLKSDGEIEASLRPKSLDDFIGQPRVREQLALVLRGAKQRGSTPDHVL
CCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEE
LSGPPGLGKTSMAMIIAAELGTALRITSGPALERAGDLAAMLSNLVEGDVLFIDEIHRIA
EECCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
RPAEEMLYLAMEDFRVDVVVGKGPGATSIPLDIAPFTLVGATTRSGALTGPLRDRFGFTG
CCHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCC
HMDFYEPGELLRILERSAQILGVRIETDAAAEIAGRSRGTPRIANRLLRRVRDYAEVRAD
CCCCCCHHHHHHHHHHCHHEEEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
GIVTLPVARAALEVYDVDTLGLDRLDRAVLDALVRGFHGGPVGVSTLAVAVGEEATTVEE
CEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHH
VCEPFLVRAGLVARTPRGRVATAAAWEHLGLVPPPDLVFGSIEVRGRTSQPTLDLFD
HHHHHHHHCCHHEECCCCCEEHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDDHDDSPVSPSFLKSDGEIEASLRPKSLDDFIGQPRVREQLALVLRGAKQRGSTPDHVL
CCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEE
LSGPPGLGKTSMAMIIAAELGTALRITSGPALERAGDLAAMLSNLVEGDVLFIDEIHRIA
EECCCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
RPAEEMLYLAMEDFRVDVVVGKGPGATSIPLDIAPFTLVGATTRSGALTGPLRDRFGFTG
CCHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCC
HMDFYEPGELLRILERSAQILGVRIETDAAAEIAGRSRGTPRIANRLLRRVRDYAEVRAD
CCCCCCHHHHHHHHHHCHHEEEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
GIVTLPVARAALEVYDVDTLGLDRLDRAVLDALVRGFHGGPVGVSTLAVAVGEEATTVEE
CEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHH
VCEPFLVRAGLVARTPRGRVATAAAWEHLGLVPPPDLVFGSIEVRGRTSQPTLDLFD
HHHHHHHHCCHHEECCCCCEEHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA