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The map label for this gene is efp

Identifier: 54025602

GI number: 54025602

Start: 3843135

End: 3843698

Strand: Reverse

Name: efp

Synonym: nfa36320

Alternate gene names: 54025602

Gene position: 3843698-3843135 (Counterclockwise)

Preceding gene: 54025603

Following gene: 54025601

Centisome position: 63.84

GC content: 65.6

Gene sequence:

>564_bases
GTGGCGGACACCAGCGACTTCAAGAACGGCCTCGTGCTGAAGATCGACGGTCAGCTCCAGCAGATCGTCGAATTCCAGCA
CGTCAAGCCGGGTAAGGGCCCTGCCTTCGTGCGGACCAAGCTGAAGAACGTCGTGTCCGGCAAGATCGTCGACAAGACGT
TCAACGCGGGCGTGAAGGTCGAGACCGCGACCGTGGACCGGCGCGACATGACCTACCTCTACCACGACGGCTCGGACTAC
GTCTTCATGGACGGCGAGACCTTCGACCAGATCTCGATCTCCGAGGCCACCATCGGCTCGAGCGCGCGTTTCCTGCTGGA
GAACATGGCGGTGCAGGTCGCGATGCACGAGGGCGCGCCGCTCTACGTCGAGCTGCCGGTCTCGGTCGAGCTCGAGGTGA
CCCACACCGACATCGGCCTGCAGGGCGACCGGTCGACCGGCGGCACCAAGCCCGCCACCCTGGAGACCGGCGCCGAGGTG
CAAGTGCCGCTGTTCATCAACACCGGCGACAAGCTGCGCATCGACTCGCGCGACGGCAGCTACCTCGGCCGGGTCAACGC
CTGA

Upstream 100 bases:

>100_bases
CGTGGTGCGTGAAGGGGGCCCGGAGCTGCTCACCCACACCAGCAAAGACCTGACCGTCGTCGATTGACGCCGGTAGCCGA
GAACAGGAGATCCGAAGACA

Downstream 100 bases:

>100_bases
TCCACGACCTCCGCGGCGGTAGCCGGATTCGCCCGTGGGCGGGACCGGCTACCGCTTCCATGCGTACAGACGGGATGATG
TGACTGTGGCCGAACAGCCC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MADTSDFKNGLVLKIDGQLQQIVEFQHVKPGKGPAFVRTKLKNVVSGKIVDKTFNAGVKVETATVDRRDMTYLYHDGSDY
VFMDGETFDQISISEATIGSSARFLLENMAVQVAMHEGAPLYVELPVSVELEVTHTDIGLQGDRSTGGTKPATLETGAEV
QVPLFINTGDKLRIDSRDGSYLGRVNA

Sequences:

>Translated_187_residues
MADTSDFKNGLVLKIDGQLQQIVEFQHVKPGKGPAFVRTKLKNVVSGKIVDKTFNAGVKVETATVDRRDMTYLYHDGSDY
VFMDGETFDQISISEATIGSSARFLLENMAVQVAMHEGAPLYVELPVSVELEVTHTDIGLQGDRSTGGTKPATLETGAEV
QVPLFINTGDKLRIDSRDGSYLGRVNA
>Mature_186_residues
ADTSDFKNGLVLKIDGQLQQIVEFQHVKPGKGPAFVRTKLKNVVSGKIVDKTFNAGVKVETATVDRRDMTYLYHDGSDYV
FMDGETFDQISISEATIGSSARFLLENMAVQVAMHEGAPLYVELPVSVELEVTHTDIGLQGDRSTGGTKPATLETGAEVQ
VPLFINTGDKLRIDSRDGSYLGRVNA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=43.4065934065934, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=32.1052631578947, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_NOCFA (Q5YTL1)

Other databases:

- EMBL:   AP006618
- RefSeq:   YP_119844.1
- ProteinModelPortal:   Q5YTL1
- SMR:   Q5YTL1
- GeneID:   3109726
- GenomeReviews:   AP006618_GR
- KEGG:   nfa:nfa36320
- NMPDR:   fig|247156.1.peg.3545
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   NFAR247156:NFA36320-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20367; Mature: 20236

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTSDFKNGLVLKIDGQLQQIVEFQHVKPGKGPAFVRTKLKNVVSGKIVDKTFNAGVKV
CCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCEEE
ETATVDRRDMTYLYHDGSDYVFMDGETFDQISISEATIGSSARFLLENMAVQVAMHEGAP
EEEECCCCCEEEEEECCCCEEEECCCCCCEEEECCCCCCCHHHHHHHCEEEEEEEECCCC
LYVELPVSVELEVTHTDIGLQGDRSTGGTKPATLETGAEVQVPLFINTGDKLRIDSRDGS
EEEEECCEEEEEEEEEECCEECCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCC
YLGRVNA
EEEEECC
>Mature Secondary Structure 
ADTSDFKNGLVLKIDGQLQQIVEFQHVKPGKGPAFVRTKLKNVVSGKIVDKTFNAGVKV
CCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCEEE
ETATVDRRDMTYLYHDGSDYVFMDGETFDQISISEATIGSSARFLLENMAVQVAMHEGAP
EEEECCCCCEEEEEECCCCEEEECCCCCCEEEECCCCCCCHHHHHHHCEEEEEEEECCCC
LYVELPVSVELEVTHTDIGLQGDRSTGGTKPATLETGAEVQVPLFINTGDKLRIDSRDGS
EEEEECCEEEEEEEEEECCEECCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCC
YLGRVNA
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA