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The map label for this gene is yqhT [H]

Identifier: 54025603

GI number: 54025603

Start: 3843732

End: 3844859

Strand: Reverse

Name: yqhT [H]

Synonym: nfa36330

Alternate gene names: 54025603

Gene position: 3844859-3843732 (Counterclockwise)

Preceding gene: 54025608

Following gene: 54025602

Centisome position: 63.86

GC content: 71.45

Gene sequence:

>1128_bases
ATGTCTGCTGATCCCGCGGGCCTGGTGCCCGACTACGCCGCGCGCCGGGGCGCGTTGCGCAGTCTGCTGGTGGAGAACGA
GGTCGACGCCCTGCTGGTCACCGATCTGGTGAACATCAGGTACCTCACCGGATTCACCGGCTCCAACGCCGCCCTGCTCG
TGCACTCGTGGGACATGCGCAACGCCGAGGACCGCACGGTGCTCGGCACCGACGGCCGCTATCGCGACCAAGTCGCCGCC
CAGGTGCCGGACCTGCGCGCCGAGATCGCCCGGGCCACCGCTCGGCGCATCGTCGAGCTGGCCGGGGAATGGCAGCTGGG
CCGGATCGGCTTCGAGAGCCATGCCGTCACCGTCGATCAGCACCGCGGCTTCGTCGAGCAGCGCACCGGACTGGAGTTCG
TCGCCACCCCCGGGCTGGTCGAACAGCTGCGCATGGTCAAGGACGCCTACGAGGTCGAACAGCTGCGCCGCGCCTGCGCG
GCGGGCGACGCCGGGCTGGCCGCCCTGCTGGCTCGCGGTGGCCTGCGCCCGGGCCGCACCGAACGCCAGGTCGCCCGCGA
CCTCGAATGGGCCATGTTCGAGCACGGCGCCGAGGCGGTCTCCTTCGAGACCATCGTCGCCACCGGCGTCAACTCCGCGA
TCCCGCATCACCGGCCCACCGACGCGGTGCTCGCCCCGGGCGATTTCGTGAAGATCGATTTCGGCGCCGTCGTGGACGGC
TACCACTCCGACATGACCCGCACCTTCGTGCTCGGCCACGCCGCCGACTGGCAGCGCGAGGTGTACGAGCTGGTCGCCGA
GGCGCAGCGGGCCGGGAGCAAGGCGCTGCGGCCCGGCGTCGCCGCGGGCGAGGTGGACGCCGCGTCCCGCTCGGTGATCG
AGGCGGCGGGCCACGGCAAGCTGTTCGTGCACGGCCTCGGGCACGGGGTCGGACTGCGCATCCACGAAGCGCCCGGAATC
GCCAAGAACGCGCCCGGTACACTTCTCTCCGGCGTGGCGGTGACCGTCGAACCAGGTGTGTACTTTCCCGGCCGCGGCGG
GGTCCGGATCGAGGACACGCTCGTGGTGCGTGAAGGGGGCCCGGAGCTGCTCACCCACACCAGCAAAGACCTGACCGTCG
TCGATTGA

Upstream 100 bases:

>100_bases
TCCCGCCGAGGTCGGCAGCCGGTCGCGGCGTCGTCCGTACCGGCGCACCGCCGCCCGTGTTGCCGTTCGCGCGTCGTGGG
CCGGGCGGTAGCTTGGAGCC

Downstream 100 bases:

>100_bases
CGCCGGTAGCCGAGAACAGGAGATCCGAAGACAGTGGCGGACACCAGCGACTTCAAGAACGGCCTCGTGCTGAAGATCGA
CGGTCAGCTCCAGCAGATCG

Product: putative peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSADPAGLVPDYAARRGALRSLLVENEVDALLVTDLVNIRYLTGFTGSNAALLVHSWDMRNAEDRTVLGTDGRYRDQVAA
QVPDLRAEIARATARRIVELAGEWQLGRIGFESHAVTVDQHRGFVEQRTGLEFVATPGLVEQLRMVKDAYEVEQLRRACA
AGDAGLAALLARGGLRPGRTERQVARDLEWAMFEHGAEAVSFETIVATGVNSAIPHHRPTDAVLAPGDFVKIDFGAVVDG
YHSDMTRTFVLGHAADWQREVYELVAEAQRAGSKALRPGVAAGEVDAASRSVIEAAGHGKLFVHGLGHGVGLRIHEAPGI
AKNAPGTLLSGVAVTVEPGVYFPGRGGVRIEDTLVVREGGPELLTHTSKDLTVVD

Sequences:

>Translated_375_residues
MSADPAGLVPDYAARRGALRSLLVENEVDALLVTDLVNIRYLTGFTGSNAALLVHSWDMRNAEDRTVLGTDGRYRDQVAA
QVPDLRAEIARATARRIVELAGEWQLGRIGFESHAVTVDQHRGFVEQRTGLEFVATPGLVEQLRMVKDAYEVEQLRRACA
AGDAGLAALLARGGLRPGRTERQVARDLEWAMFEHGAEAVSFETIVATGVNSAIPHHRPTDAVLAPGDFVKIDFGAVVDG
YHSDMTRTFVLGHAADWQREVYELVAEAQRAGSKALRPGVAAGEVDAASRSVIEAAGHGKLFVHGLGHGVGLRIHEAPGI
AKNAPGTLLSGVAVTVEPGVYFPGRGGVRIEDTLVVREGGPELLTHTSKDLTVVD
>Mature_374_residues
SADPAGLVPDYAARRGALRSLLVENEVDALLVTDLVNIRYLTGFTGSNAALLVHSWDMRNAEDRTVLGTDGRYRDQVAAQ
VPDLRAEIARATARRIVELAGEWQLGRIGFESHAVTVDQHRGFVEQRTGLEFVATPGLVEQLRMVKDAYEVEQLRRACAA
GDAGLAALLARGGLRPGRTERQVARDLEWAMFEHGAEAVSFETIVATGVNSAIPHHRPTDAVLAPGDFVKIDFGAVVDGY
HSDMTRTFVLGHAADWQREVYELVAEAQRAGSKALRPGVAAGEVDAASRSVIEAAGHGKLFVHGLGHGVGLRIHEAPGIA
KNAPGTLLSGVAVTVEPGVYFPGRGGVRIEDTLVVREGGPELLTHTSKDLTVVD

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=261, Percent_Identity=27.2030651340996, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI264681563, Length=306, Percent_Identity=30.3921568627451, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI93141226, Length=172, Percent_Identity=31.9767441860465, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI260593665, Length=243, Percent_Identity=30.0411522633745, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI149589008, Length=297, Percent_Identity=28.2828282828283, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI260593663, Length=243, Percent_Identity=30.0411522633745, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI164420681, Length=250, Percent_Identity=26.4, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI264681565, Length=303, Percent_Identity=29.042904290429, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40385867, Length=226, Percent_Identity=26.1061946902655, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788728, Length=360, Percent_Identity=35.8333333333333, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789275, Length=255, Percent_Identity=32.156862745098, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786364, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790282, Length=300, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508215, Length=289, Percent_Identity=30.1038062283737, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71996291, Length=243, Percent_Identity=27.9835390946502, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320922, Length=250, Percent_Identity=27.2, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321118, Length=290, Percent_Identity=25.1724137931034, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323273, Length=247, Percent_Identity=27.5303643724696, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322999, Length=347, Percent_Identity=23.342939481268, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920384, Length=254, Percent_Identity=25.5905511811024, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357079, Length=294, Percent_Identity=26.8707482993197, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355531, Length=187, Percent_Identity=28.3422459893048, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40150; Mature: 40019

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00491 PROLINE_PEPTIDASE ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADPAGLVPDYAARRGALRSLLVENEVDALLVTDLVNIRYLTGFTGSNAALLVHSWDMR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCCCEEEEEECCCC
NAEDRTVLGTDGRYRDQVAAQVPDLRAEIARATARRIVELAGEWQLGRIGFESHAVTVDQ
CCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECEECCCCCEEEEHH
HRGFVEQRTGLEFVATPGLVEQLRMVKDAYEVEQLRRACAAGDAGLAALLARGGLRPGRT
HCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCH
ERQVARDLEWAMFEHGAEAVSFETIVATGVNSAIPHHRPTDAVLAPGDFVKIDFGAVVDG
HHHHHHHHHHHHHHCCCCCEEHHHHEECCCCCCCCCCCCCCCEECCCCEEEEEHHHEECC
YHSDMTRTFVLGHAADWQREVYELVAEAQRAGSKALRPGVAAGEVDAASRSVIEAAGHGK
HHHCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHCCCCE
LFVHGLGHGVGLRIHEAPGIAKNAPGTLLSGVAVTVEPGVYFPGRGGVRIEDTLVVREGG
EEEEECCCCCEEEEECCCCCCCCCCCHHHCCEEEEECCCEEECCCCCCEEEEEEEEECCC
PELLTHTSKDLTVVD
CHHHHCCCCCEEEEC
>Mature Secondary Structure 
SADPAGLVPDYAARRGALRSLLVENEVDALLVTDLVNIRYLTGFTGSNAALLVHSWDMR
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCCCEEEEEECCCC
NAEDRTVLGTDGRYRDQVAAQVPDLRAEIARATARRIVELAGEWQLGRIGFESHAVTVDQ
CCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECEECCCCCEEEEHH
HRGFVEQRTGLEFVATPGLVEQLRMVKDAYEVEQLRRACAAGDAGLAALLARGGLRPGRT
HCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCH
ERQVARDLEWAMFEHGAEAVSFETIVATGVNSAIPHHRPTDAVLAPGDFVKIDFGAVVDG
HHHHHHHHHHHHHHCCCCCEEHHHHEECCCCCCCCCCCCCCCEECCCCEEEEEHHHEECC
YHSDMTRTFVLGHAADWQREVYELVAEAQRAGSKALRPGVAAGEVDAASRSVIEAAGHGK
HHHCCEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHCCCCE
LFVHGLGHGVGLRIHEAPGIAKNAPGTLLSGVAVTVEPGVYFPGRGGVRIEDTLVVREGG
EEEEECCCCCEEEEECCCCCCCCCCCHHHCCEEEEECCCEEECCCCCCEEEEEEEEECCC
PELLTHTSKDLTVVD
CHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]