Click here to switch to the map view.

The map label for this gene is dnaC

Identifier: 54020645

GI number: 54020645

Start: 836667

End: 838058

Strand: Reverse

Name: dnaC

Synonym: mhp664

Alternate gene names: 54020645

Gene position: 838058-836667 (Counterclockwise)

Preceding gene: 54020646

Following gene: 54020644

Centisome position: 93.87

GC content: 29.96

Gene sequence:

>1392_bases
ATGAATAATTCTCGTTATAATTCTCCTGAACTTGAAGCATTTATCATCTCTTTTCTTTTAGCAAATCCTGAAAAAGTTGT
TAATTTTATTGACATACTTAATCCAGATGATTTCAGTGTTAGAAATTTAGCTGAAATTGTAAGAGCAATAAAAAATGTTG
CAAATCAAACAAAAAATCCTGAGGTTACCCTAGTTCTTCAGGAACTCGAAAGAACGGGTAAATTAGATCAAATCGGCGGG
CGCAACTACATTGTAAATTTATATAACAGCAATTTTTCGCTACCTTCGGAAATCACTGAGCATTTAAGAATAATAAATGA
AAAAAAAACTTTAAGAGATCTAAAAAAAATTGTTGATGATTCAACAAAAGAACTAAATTCCGGAACAAAATTTTCTTATG
AGATAACCACAGAAATTCTTCAAAAAATAAATCTTCTGAATTTTAATACTAAAAATGAAACTTTTATTCCGATTTATGAG
ATTGCAGTTCAAATTTTCGCATATTTAACAGAATTACGTACGAGTCAAAATTTAATTAAAGGAATTTCGACTGGATATGA
GAATTTAGACTTATTAACTTCTGGATTTCAAAAAGGTGATCTAACTATTTTAGCAGCCCGGCCTTCAGTCGGAAAAACAG
CTTTTGCCCTTAATTTAGCTTGAAATATTTGTGAAAATGGTAAATCTGTCCTATTTTTTGCACTTGAAATGTCTAATTCT
GATTTAGTTACAAGACTTCTTTCGCTTATTTCTGGGGTTGAATCAGGAAAATTTAAAATCCCAAAAAATTTAAGAGCTGA
AGATTTAAAAGCAATCGAAAAGGCAATTGAAACCCGAATTAAAAACTGTAAATTAATAATTAATGACTCTGGATCGATTA
ATATTGATGATATTTACTGACAAGTTCAAAAAAGATATCGAAATAACCTAAAATATGATTTAATTATTTTTGATTATTTA
CAACTAATTAATTCAGCTACAAGAAACCAAAATTATAACCGTCAAGTCGAGGTATCAATTATTTCAAGAAAATTAAAACA
ACTAGCTCGTGAAGTCGAAACTCCAATTTTAGCACTTTCACAACTTTCAAGAAATGTTGAAAGAAGAGAGGATAAAACCC
CAGTTCTATCGGATTTAAGGGAATCTGGAGCAATTGAACAAGATGCTGATATTGTCGCTTTTCTACATCGTGAGGATTAT
TATCACAAAAAAGAGGAGAAACCCGATCAAGAACAGGGCCCAAATACGAAACTTATAATTGCAAAACATAGAAATGGACC
GATTGGAACTTTATTTTTTGATTTTTTTCCTGAATTTGGCAAGTTTAGTCCTGCAATTCCGGAGTCTTCATATAATAAAA
AACCAAATATTAATTTAGGATTGGATGAATAA

Upstream 100 bases:

>100_bases
GCAATCCAAACAAGTGGAATTTCCACTTTTGGCACTAGTTTTGTTGATATAAAATTAAGTTCTCAAACTATTGCTAAATT
AAAAATAAATATCACAAAAG

Downstream 100 bases:

>100_bases
TGGCCTTATATTTTGCTATTTTATCCGTTGTTTTAGTGATTTTATTCTTTATTTCGGCAATTTTTTCTGCAAGCGAGACC
GTATTTACTGCAACAAGTCG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNNSRYNSPELEAFIISFLLANPEKVVNFIDILNPDDFSVRNLAEIVRAIKNVANQTKNPEVTLVLQELERTGKLDQIGG
RNYIVNLYNSNFSLPSEITEHLRIINEKKTLRDLKKIVDDSTKELNSGTKFSYEITTEILQKINLLNFNTKNETFIPIYE
IAVQIFAYLTELRTSQNLIKGISTGYENLDLLTSGFQKGDLTILAARPSVGKTAFALNLAWNICENGKSVLFFALEMSNS
DLVTRLLSLISGVESGKFKIPKNLRAEDLKAIEKAIETRIKNCKLIINDSGSINIDDIYWQVQKRYRNNLKYDLIIFDYL
QLINSATRNQNYNRQVEVSIISRKLKQLAREVETPILALSQLSRNVERREDKTPVLSDLRESGAIEQDADIVAFLHREDY
YHKKEEKPDQEQGPNTKLIIAKHRNGPIGTLFFDFFPEFGKFSPAIPESSYNKKPNINLGLDE

Sequences:

>Translated_463_residues
MNNSRYNSPELEAFIISFLLANPEKVVNFIDILNPDDFSVRNLAEIVRAIKNVANQTKNPEVTLVLQELERTGKLDQIGG
RNYIVNLYNSNFSLPSEITEHLRIINEKKTLRDLKKIVDDSTKELNSGTKFSYEITTEILQKINLLNFNTKNETFIPIYE
IAVQIFAYLTELRTSQNLIKGISTGYENLDLLTSGFQKGDLTILAARPSVGKTAFALNLA*NICENGKSVLFFALEMSNS
DLVTRLLSLISGVESGKFKIPKNLRAEDLKAIEKAIETRIKNCKLIINDSGSINIDDIY*QVQKRYRNNLKYDLIIFDYL
QLINSATRNQNYNRQVEVSIISRKLKQLAREVETPILALSQLSRNVERREDKTPVLSDLRESGAIEQDADIVAFLHREDY
YHKKEEKPDQEQGPNTKLIIAKHRNGPIGTLFFDFFPEFGKFSPAIPESSYNKKPNINLGLDE
>Mature_463_residues
MNNSRYNSPELEAFIISFLLANPEKVVNFIDILNPDDFSVRNLAEIVRAIKNVANQTKNPEVTLVLQELERTGKLDQIGG
RNYIVNLYNSNFSLPSEITEHLRIINEKKTLRDLKKIVDDSTKELNSGTKFSYEITTEILQKINLLNFNTKNETFIPIYE
IAVQIFAYLTELRTSQNLIKGISTGYENLDLLTSGFQKGDLTILAARPSVGKTAFALNLA*NICENGKSVLFFALEMSNS
DLVTRLLSLISGVESGKFKIPKNLRAEDLKAIEKAIETRIKNCKLIINDSGSINIDDIY*QVQKRYRNNLKYDLIIFDYL
QLINSATRNQNYNRQVEVSIISRKLKQLAREVETPILALSQLSRNVERREDKTPVLSDLRESGAIEQDADIVAFLHREDY
YHKKEEKPDQEQGPNTKLIIAKHRNGPIGTLFFDFFPEFGKFSPAIPESSYNKKPNINLGLDE

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=442, Percent_Identity=30.7692307692308, Blast_Score=201, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 52497; Mature: 52497

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSRYNSPELEAFIISFLLANPEKVVNFIDILNPDDFSVRNLAEIVRAIKNVANQTKNP
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EVTLVLQELERTGKLDQIGGRNYIVNLYNSNFSLPSEITEHLRIINEKKTLRDLKKIVDD
CEEEEEHHHHHCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
STKELNSGTKFSYEITTEILQKINLLNFNTKNETFIPIYEIAVQIFAYLTELRTSQNLIK
CHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GISTGYENLDLLTSGFQKGDLTILAARPSVGKTAFALNLANICENGKSVLFFALEMSNSD
HHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCH
LVTRLLSLISGVESGKFKIPKNLRAEDLKAIEKAIETRIKNCKLIINDSGSINIDDIYQV
HHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHH
QKRYRNNLKYDLIIFDYLQLINSATRNQNYNRQVEVSIISRKLKQLAREVETPILALSQL
HHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SRNVERREDKTPVLSDLRESGAIEQDADIVAFLHREDYYHKKEEKPDQEQGPNTKLIIAK
HHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEEE
HRNGPIGTLFFDFFPEFGKFSPAIPESSYNKKPNINLGLDE
CCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNNSRYNSPELEAFIISFLLANPEKVVNFIDILNPDDFSVRNLAEIVRAIKNVANQTKNP
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EVTLVLQELERTGKLDQIGGRNYIVNLYNSNFSLPSEITEHLRIINEKKTLRDLKKIVDD
CEEEEEHHHHHCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
STKELNSGTKFSYEITTEILQKINLLNFNTKNETFIPIYEIAVQIFAYLTELRTSQNLIK
CHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GISTGYENLDLLTSGFQKGDLTILAARPSVGKTAFALNLANICENGKSVLFFALEMSNSD
HHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCH
LVTRLLSLISGVESGKFKIPKNLRAEDLKAIEKAIETRIKNCKLIINDSGSINIDDIYQV
HHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHH
QKRYRNNLKYDLIIFDYLQLINSATRNQNYNRQVEVSIISRKLKQLAREVETPILALSQL
HHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SRNVERREDKTPVLSDLRESGAIEQDADIVAFLHREDYYHKKEEKPDQEQGPNTKLIIAK
HHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEEE
HRNGPIGTLFFDFFPEFGKFSPAIPESSYNKKPNINLGLDE
CCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]