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The map label for this gene is udg2

Identifier: 53722852

GI number: 53722852

Start: 2492704

End: 2494125

Strand: Reverse

Name: udg2

Synonym: BPSS1833

Alternate gene names: 53722852

Gene position: 2494125-2492704 (Counterclockwise)

Preceding gene: 53722853

Following gene: 53722851

Centisome position: 78.6

GC content: 69.13

Gene sequence:

>1422_bases
ATGAATCTGACTATCATCGGCAGCGGTTATGTAGGGCTCGTCACCGGCGCGTGTCTCGCGGACATCGGCCACGACGTGTT
CTGTCTCGACGTCGACAGCAAGAAGATCGACGTCCTGAACAACGGCGGCGTGCCGATTCACGAGCCGGGGCTCGGGGAGA
TCATCGCGCGCAACCGCGCGGCGGGCCGCCTGCAGTTCTCGACCGACGTCGAGGCGGCCGTCGCGCACGGCGACGTGCAG
TTCATCGCGGTCGGCACGCCGCCCGACGAGGACGGCTCCGCGGACCTGCAGTACGTGCTTGCCGCCGCCCGCAACATCGG
CCGCCACATGAACGGGTTCAAGGTGATCGTCGACAAGTCGACGGTGCCCGTCGGCACGGCCGAGCGCGTGCGCGCGGCGG
TCGCGGACGAGCTGAAGGCGCGCGGCGAGGATTCGATGTTCTCGGTCGTGTCGAACCCCGAGTTCCTGAAGGAGGGGGCG
GCCGTCGAGGATTTCACGCGGCCCGACCGGATCGTGATCGGCTGCGACGACGACGTGCCCGGCGAGCGCGCGCGCGAGCT
GATGAAGAAGCTCTATGCGCCGTTCAATCGCAATCACGAACGCACGCTCTACATGGACGTGCGCTCGGCCGAGTTCACGA
AGTATGCGGCGAACGCGATGCTCGCGACGCGCATCTCGTTCATGAACGAGCTCGCGAATCTCGCGGAGCGCTTCGGCGCG
GACATCGAGGCGGTGCGGCGCGGAATCGGCTCCGATCCGCGCATCGGCTATCACTTCCTGTACGCGGGCTGCGGCTACGG
CGGTTCGTGCTTTCCGAAGGACGTCGAAGCGCTGATCCGCACGGCGGCCGAGCATGGGCAGGCGCTGCGCGTGCTGCAGG
CGGTGTCCGCCGTCAACGACGAGCAAAAGCACGTGCTCGCGAGGAAAGTCGTCGCGCGCTTCGGCGGCGATCTGACGGGC
CGGCGCTTCGGCGTGTGGGGGCTCGCGTTCAAGCCGAACACCGACGACATGCGCGAAGCGCCGAGCCGCGCGCTGATCGC
GGCGCTGCTGTCGCGCGGCGCGCACGTCGTCGCCTACGATCCGGTCGCGCAGGACGAAGCGCGGCGCGTGCTCGCGATCG
ATCTGGGCGAGTACCCGGATGCGCTCGGGCGGCTCGCGTTCGCCGACGACGAGGCGCAGGTGGCGCAGGACGCGGACGCG
CTCGTGATCGTCACCGAATGGAAGGCGTTCAAGAGTCCGGATTTCGCGGCGCTCGGCAAGCGCTGGAAAACGCCCGTGAT
TTTCGACGGACGCAATCTGTACGAGCCGATCGCGATGCGCGAGCTCGGCATCGAGTACTACCCGATCGGGCGGCCCGGCG
CGGCGCCGCGCACGGCGGCGGGCGAGTCCGACGCCGCTCGCGCCGCGCGCGCCGGCGCGTGA

Upstream 100 bases:

>100_bases
CAAGATCGTCGCGCTGACGTTGTGGAAAGGCTTCACCGGCAGCAACGCGTATTGAGCGCGGTCATGCGCTTACGACTCAC
TGGGTAAAGAGGTTCGACAG

Downstream 100 bases:

>100_bases
GCGGGCCGCCACGGGTTCGAGCATGTTTCGCAACATTCTGATCGTATGCCGCGCGAACGTGTGCCGCAGCCCGGCCGCGG
AGCTGCTGTTCAGGTCGATG

Product: UDP-glucose 6-dehydrogenase 2

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDSKKIDVLNNGGVPIHEPGLGEIIARNRAAGRLQFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKSTVPVGTAERVRAAVADELKARGEDSMFSVVSNPEFLKEGA
AVEDFTRPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLAERFGA
DIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTAAEHGQALRVLQAVSAVNDEQKHVLARKVVARFGGDLTG
RRFGVWGLAFKPNTDDMREAPSRALIAALLSRGAHVVAYDPVAQDEARRVLAIDLGEYPDALGRLAFADDEAQVAQDADA
LVIVTEWKAFKSPDFAALGKRWKTPVIFDGRNLYEPIAMRELGIEYYPIGRPGAAPRTAAGESDAARAARAGA

Sequences:

>Translated_473_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDSKKIDVLNNGGVPIHEPGLGEIIARNRAAGRLQFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKSTVPVGTAERVRAAVADELKARGEDSMFSVVSNPEFLKEGA
AVEDFTRPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLAERFGA
DIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTAAEHGQALRVLQAVSAVNDEQKHVLARKVVARFGGDLTG
RRFGVWGLAFKPNTDDMREAPSRALIAALLSRGAHVVAYDPVAQDEARRVLAIDLGEYPDALGRLAFADDEAQVAQDADA
LVIVTEWKAFKSPDFAALGKRWKTPVIFDGRNLYEPIAMRELGIEYYPIGRPGAAPRTAAGESDAARAARAGA
>Mature_473_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDSKKIDVLNNGGVPIHEPGLGEIIARNRAAGRLQFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKSTVPVGTAERVRAAVADELKARGEDSMFSVVSNPEFLKEGA
AVEDFTRPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLAERFGA
DIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTAAEHGQALRVLQAVSAVNDEQKHVLARKVVARFGGDLTG
RRFGVWGLAFKPNTDDMREAPSRALIAALLSRGAHVVAYDPVAQDEARRVLAIDLGEYPDALGRLAFADDEAQVAQDADA
LVIVTEWKAFKSPDFAALGKRWKTPVIFDGRNLYEPIAMRELGIEYYPIGRPGAAPRTAAGESDAARAARAGA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=473, Percent_Identity=35.9408033826639, Blast_Score=269, Evalue=4e-72,
Organism=Homo sapiens, GI296040438, Length=376, Percent_Identity=36.436170212766, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI296040443, Length=323, Percent_Identity=36.2229102167183, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1788340, Length=370, Percent_Identity=29.1891891891892, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI48994968, Length=426, Percent_Identity=27.9342723004695, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=464, Percent_Identity=34.9137931034483, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17136908, Length=465, Percent_Identity=34.8387096774194, Blast_Score=250, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 51046; Mature: 51046

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDSKKIDVLNNGGVPIHEPGLGEIIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHCCCC
AGRLQFSTDVEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKS
CCEEEECCCHHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTAERVRAAVADELKARGEDSMFSVVSNPEFLKEGAAVEDFTRPDRIVIGCDDDVP
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCHHHCCCCCEEEEECCCCCC
GERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLAERFGA
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTAAEHGQALRVLQAVSAVND
CHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EQKHVLARKVVARFGGDLTGRRFGVWGLAFKPNTDDMREAPSRALIAALLSRGAHVVAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
PVAQDEARRVLAIDLGEYPDALGRLAFADDEAQVAQDADALVIVTEWKAFKSPDFAALGK
CCCCCCCCEEEEEECCCCHHHHCCEEECCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
RWKTPVIFDGRNLYEPIAMRELGIEYYPIGRPGAAPRTAAGESDAARAARAGA
CCCCCEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDSKKIDVLNNGGVPIHEPGLGEIIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHCCCC
AGRLQFSTDVEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRHMNGFKVIVDKS
CCEEEECCCHHHHEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECC
TVPVGTAERVRAAVADELKARGEDSMFSVVSNPEFLKEGAAVEDFTRPDRIVIGCDDDVP
CCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCHHHCCCCCEEEEECCCCCC
GERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLAERFGA
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTAAEHGQALRVLQAVSAVND
CHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EQKHVLARKVVARFGGDLTGRRFGVWGLAFKPNTDDMREAPSRALIAALLSRGAHVVAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEC
PVAQDEARRVLAIDLGEYPDALGRLAFADDEAQVAQDADALVIVTEWKAFKSPDFAALGK
CCCCCCCCEEEEEECCCCHHHHCCEEECCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
RWKTPVIFDGRNLYEPIAMRELGIEYYPIGRPGAAPRTAAGESDAARAARAGA
CCCCCEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]