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The map label for this gene is gapA [H]

Identifier: 52787350

GI number: 52787350

Start: 3491334

End: 3492341

Strand: Reverse

Name: gapA [H]

Synonym: BLi03665

Alternate gene names: 52787350

Gene position: 3492341-3491334 (Counterclockwise)

Preceding gene: 52787351

Following gene: 52787349

Centisome position: 82.71

GC content: 44.74

Gene sequence:

>1008_bases
ATGGCAGTAAAAGTCGGTATTAATGGTTTTGGTCGTATTGGACGCAATGTATTCCGCGCAGCATTAAATAATCCTGAAGT
TGAGGTTGTGGCAGTTAACGATTTGACAGACGCTAACATGCTTGCTCACCTATTACAATATGATTCAGTACATGGAAAAT
TGGACGCAGAGGTTTCTGTTGACGGAAGCAACCTTGTTGTTAACGGTCAAACAATCCAAGTTACAGCAGAGCGCGATCCT
TCTAAACTAAGCTGGGGAGAGCAAGGTGTTGAAATCGTTGTTGAATCAACTGGTTTCTTCACAAAACGCGCAGATGCGGC
GAAACATTTGGAAGCCGGCGCGAAAAAAGTTATCATCTCAGCTCCTGCGAGTGAAGAAGATATTACAATCGTTATGGGTG
TTAACGAAGATAAATACGATGCGGCTAACCACCATGTTATCTCTAACGCATCTTGCACAACAAACTGCCTTGCGCCGTTT
GCAAAAGTTCTGAACGACAAATTCGGCATCAAACGCGGTATGATGACAACTGTTCACTCTTACACAAACGATCAGCAAAT
CCTGGATCTTCCGCACAAAGACTACCGTCGTGCGCGTGCGGCAGCTGAGAGCATCATTCCTACAACAACTGGTGCTGCGA
AAGCCGTTTCCCTTGTACTTCCTGAACTGAAAGGAAAACTGAACGGCGGAGCAATGCGTGTTCCAACACCAAACGTATCA
CTTGTTGACCTGGTTGCTGAACTTGACAAAGAAGTAACAGCAGAAGAAGTAAACGCAGCGCTTAAAGAAGCAGCAGAAGG
CGAACTTCAAGGCGTTCTTGGCTACAGCGAAGAGCCGCTTGTATCTAAAGACTACAACGGCAATACAAACTCTTCTACAA
TCGATGCTCTTTCTACAATGGTTATGGAAGGCAGCATGGTTAAAGTTATTTCTTGGTATGACAACGAAAGCGGATATTCT
CACCGTGTTGTTGACCTTGCCGCTTACATCGCAAAACAAGGTCTTTAA

Upstream 100 bases:

>100_bases
TTTGATCACTGATGAAGGAGCCGCAAAACAGTTATTAAGGGAAGCTTCTTCCCTCAATATAAATTAAATATCTCTTATTT
ACTTAAAGGAGGAAATCATC

Downstream 100 bases:

>100_bases
TCCGGAAACCAGAATCAGACTTGGTTCTTGATGAGAGAAGCGCTATAATGAAAGCGGACAAGGGAAGGGGACACACACTC
CCTTTCCCTTTTTCCATATC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLLQYDSVHGKLDAEVSVDGSNLVVNGQTIQVTAERDP
SKLSWGEQGVEIVVESTGFFTKRADAAKHLEAGAKKVIISAPASEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPF
AKVLNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAESIIPTTTGAAKAVSLVLPELKGKLNGGAMRVPTPNVS
LVDLVAELDKEVTAEEVNAALKEAAEGELQGVLGYSEEPLVSKDYNGNTNSSTIDALSTMVMEGSMVKVISWYDNESGYS
HRVVDLAAYIAKQGL

Sequences:

>Translated_335_residues
MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLLQYDSVHGKLDAEVSVDGSNLVVNGQTIQVTAERDP
SKLSWGEQGVEIVVESTGFFTKRADAAKHLEAGAKKVIISAPASEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPF
AKVLNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAESIIPTTTGAAKAVSLVLPELKGKLNGGAMRVPTPNVS
LVDLVAELDKEVTAEEVNAALKEAAEGELQGVLGYSEEPLVSKDYNGNTNSSTIDALSTMVMEGSMVKVISWYDNESGYS
HRVVDLAAYIAKQGL
>Mature_334_residues
AVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLLQYDSVHGKLDAEVSVDGSNLVVNGQTIQVTAERDPS
KLSWGEQGVEIVVESTGFFTKRADAAKHLEAGAKKVIISAPASEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPFA
KVLNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAESIIPTTTGAAKAVSLVLPELKGKLNGGAMRVPTPNVSL
VDLVAELDKEVTAEEVNAALKEAAEGELQGVLGYSEEPLVSKDYNGNTNSSTIDALSTMVMEGSMVKVISWYDNESGYSH
RVVDLAAYIAKQGL

Specific function: More active in catabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=53.7537537537538, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI7657116, Length=328, Percent_Identity=49.0853658536585, Blast_Score=321, Evalue=7e-88,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=55.5555555555556, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=44.3768996960486, Blast_Score=295, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=52.0833333333333, Blast_Score=344, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=52.0833333333333, Blast_Score=344, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=50.7418397626113, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=50.7418397626113, Blast_Score=342, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=53.9156626506024, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=53.3132530120482, Blast_Score=353, Evalue=3e-98,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=52.1084337349398, Blast_Score=347, Evalue=1e-96,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=52.710843373494, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=52.710843373494, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=52.4096385542169, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=52.4096385542169, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=49.8470948012232, Blast_Score=327, Evalue=6e-90,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35886; Mature: 35755

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLLQYDSVHGKLDAEVSV
CEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEE
DGSNLVVNGQTIQVTAERDPSKLSWGEQGVEIVVESTGFFTKRADAAKHLEAGAKKVIIS
CCCEEEEECEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCEEEEE
APASEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPFAKVLNDKFGIKRGMMTTVHS
CCCCCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCHHHCHHHHHHH
YTNDQQILDLPHKDYRRARAAAESIIPTTTGAAKAVSLVLPELKGKLNGGAMRVPTPNVS
CCCCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCH
LVDLVAELDKEVTAEEVNAALKEAAEGELQGVLGYSEEPLVSKDYNGNTNSSTIDALSTM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
VMEGSMVKVISWYDNESGYSHRVVDLAAYIAKQGL
HHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLLQYDSVHGKLDAEVSV
EEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEE
DGSNLVVNGQTIQVTAERDPSKLSWGEQGVEIVVESTGFFTKRADAAKHLEAGAKKVIIS
CCCEEEEECEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCEEEEE
APASEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPFAKVLNDKFGIKRGMMTTVHS
CCCCCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCHHHCHHHHHHH
YTNDQQILDLPHKDYRRARAAAESIIPTTTGAAKAVSLVLPELKGKLNGGAMRVPTPNVS
CCCCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCH
LVDLVAELDKEVTAEEVNAALKEAAEGELQGVLGYSEEPLVSKDYNGNTNSSTIDALSTM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
VMEGSMVKVISWYDNESGYSHRVVDLAAYIAKQGL
HHCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493629; 9384377; 8755892; 10658653; 10799476 [H]