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The map label for this gene is yiaY [H]

Identifier: 52787193

GI number: 52787193

Start: 3340899

End: 3341894

Strand: Reverse

Name: yiaY [H]

Synonym: BLi03502

Alternate gene names: 52787193

Gene position: 3341894-3340899 (Counterclockwise)

Preceding gene: 52787194

Following gene: 52787192

Centisome position: 79.14

GC content: 47.59

Gene sequence:

>996_bases
ATGAAAACGCTTTATCATTTTCGAACGGCCGCCCGAATTGAGGCTGGTCCACATTCACTCAATTTGCTCGGCGATTACTT
AGATCAAATTGGATTGAATCAGATTCGTTCGGTGTTTATTTTAACTCAGCCGTCGATCGTCTCTCTCGGCTATGCAGACC
AAATTAAAGAAGGGCTTGCAAAGAAAGGCATCTCAAGTGAAGTCAACACGGATATACAGCCTGAGCCGACGGAGCAAAAT
ATCGAACAGGTTTTTCAGCTTTTTTCTGAAGGAGGCCATGACGCGATTTTGGGAATTGGCGGAGGCAGTGTGCTTGATGC
GGCTAAAATCCTCTCTGTTCTGAAAACAAATGAAAAACCGATTTCTGCTTTGATTGGCACGAATCTCGTTGAAAAGCCCG
GCGTTCCGCTTGTGCTGATTCCGACAACATCCGGAACAGGGTCAGAAGTGACGCCGAATGCGATTGTAACGTTCCCTGAG
AAAGAATTAAAGATTGGTATAGTCAGTCCCTATCTGCTGCCGTCGCTTGTGATTTTAGATCCAGTTTTGACGACCGGACT
TCCAAAGGCAATCACAGCTGCAACCGGAATGGATGCATTTACACACGCACTCGAATCCTATATTTCCAACAAAGCAAATC
CATTCAGCGACATGTTTGCGCTTGAATCTATGAGACTGATTTCCTCCAGCATTCAGCAGGCCTACCATCATGGAGATAAC
CTGGAGGCGAGAGAAAAAATGCTCATTGGCGCCATGTATGGCGGAATGGCCTTGACAAGCGCAGGAACAGCGGCGGTTCA
TGCGATGGCTTACCCTCTAGGGGGAAAATACAAGATTTCGCACGGTGTGGCCAATTCAATGCTGCTTCCGCATGTAACGG
CCTTCAACGCGGATCATGTAACTGACCGCCTTTCGGACGTGGCCGGCGTAATTGGAATCGAGCCAAAAGGTTCGAAGTCC
AGCCAAGCAGAGCGGGTTATACGAAAAATTGAATAG

Upstream 100 bases:

>100_bases
CGTCCGATTGCAGAACTGTCGGGAGAGCCGCTGCTAAAAGTGAAAAAGATGCTGGAAGGCTACGGAATTGAAGCAAAACT
GGCAAAGGAGCAGTAAGATT

Downstream 100 bases:

>100_bases
TGGACCGCCGATTTAAATATTCCGCAAAATTTAAAGACATTCGGGGTATCAAAAGAGGATGTGCCATCGCTTGCTGAGGC
GGCTGCCGACGTCAAAAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKTLYHFRTAARIEAGPHSLNLLGDYLDQIGLNQIRSVFILTQPSIVSLGYADQIKEGLAKKGISSEVNTDIQPEPTEQN
IEQVFQLFSEGGHDAILGIGGGSVLDAAKILSVLKTNEKPISALIGTNLVEKPGVPLVLIPTTSGTGSEVTPNAIVTFPE
KELKIGIVSPYLLPSLVILDPVLTTGLPKAITAATGMDAFTHALESYISNKANPFSDMFALESMRLISSSIQQAYHHGDN
LEAREKMLIGAMYGGMALTSAGTAAVHAMAYPLGGKYKISHGVANSMLLPHVTAFNADHVTDRLSDVAGVIGIEPKGSKS
SQAERVIRKIE

Sequences:

>Translated_331_residues
MKTLYHFRTAARIEAGPHSLNLLGDYLDQIGLNQIRSVFILTQPSIVSLGYADQIKEGLAKKGISSEVNTDIQPEPTEQN
IEQVFQLFSEGGHDAILGIGGGSVLDAAKILSVLKTNEKPISALIGTNLVEKPGVPLVLIPTTSGTGSEVTPNAIVTFPE
KELKIGIVSPYLLPSLVILDPVLTTGLPKAITAATGMDAFTHALESYISNKANPFSDMFALESMRLISSSIQQAYHHGDN
LEAREKMLIGAMYGGMALTSAGTAAVHAMAYPLGGKYKISHGVANSMLLPHVTAFNADHVTDRLSDVAGVIGIEPKGSKS
SQAERVIRKIE
>Mature_331_residues
MKTLYHFRTAARIEAGPHSLNLLGDYLDQIGLNQIRSVFILTQPSIVSLGYADQIKEGLAKKGISSEVNTDIQPEPTEQN
IEQVFQLFSEGGHDAILGIGGGSVLDAAKILSVLKTNEKPISALIGTNLVEKPGVPLVLIPTTSGTGSEVTPNAIVTFPE
KELKIGIVSPYLLPSLVILDPVLTTGLPKAITAATGMDAFTHALESYISNKANPFSDMFALESMRLISSSIQQAYHHGDN
LEAREKMLIGAMYGGMALTSAGTAAVHAMAYPLGGKYKISHGVANSMLLPHVTAFNADHVTDRLSDVAGVIGIEPKGSKS
SQAERVIRKIE

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=330, Percent_Identity=28.1818181818182, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI48994951, Length=314, Percent_Identity=36.3057324840764, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1789163, Length=304, Percent_Identity=32.5657894736842, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI87082107, Length=293, Percent_Identity=36.1774744027304, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1787493, Length=333, Percent_Identity=30.6306306306306, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789386, Length=266, Percent_Identity=25.5639097744361, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17537053, Length=248, Percent_Identity=27.8225806451613, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321181, Length=283, Percent_Identity=35.6890459363958, Blast_Score=189, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24657991, Length=362, Percent_Identity=29.5580110497238, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 35197; Mature: 35197

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLYHFRTAARIEAGPHSLNLLGDYLDQIGLNQIRSVFILTQPSIVSLGYADQIKEGLA
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHEEEEEECCCEEECCCHHHHHHHHH
KKGISSEVNTDIQPEPTEQNIEQVFQLFSEGGHDAILGIGGGSVLDAAKILSVLKTNEKP
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCH
ISALIGTNLVEKPGVPLVLIPTTSGTGSEVTPNAIVTFPEKELKIGIVSPYLLPSLVILD
HHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECHHHHHHHHHHH
PVLTTGLPKAITAATGMDAFTHALESYISNKANPFSDMFALESMRLISSSIQQAYHHGDN
HHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LEAREKMLIGAMYGGMALTSAGTAAVHAMAYPLGGKYKISHGVANSMLLPHVTAFNADHV
CCHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCEEECCCCHHHHHHCHHHHCCCHHH
TDRLSDVAGVIGIEPKGSKSSQAERVIRKIE
HHHHHHHHHHEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTLYHFRTAARIEAGPHSLNLLGDYLDQIGLNQIRSVFILTQPSIVSLGYADQIKEGLA
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHEEEEEECCCEEECCCHHHHHHHHH
KKGISSEVNTDIQPEPTEQNIEQVFQLFSEGGHDAILGIGGGSVLDAAKILSVLKTNEKP
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCH
ISALIGTNLVEKPGVPLVLIPTTSGTGSEVTPNAIVTFPEKELKIGIVSPYLLPSLVILD
HHHHHCCCHHCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECHHHHHHHHHHH
PVLTTGLPKAITAATGMDAFTHALESYISNKANPFSDMFALESMRLISSSIQQAYHHGDN
HHHHCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LEAREKMLIGAMYGGMALTSAGTAAVHAMAYPLGGKYKISHGVANSMLLPHVTAFNADHV
CCHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCEEECCCCHHHHHHCHHHHCCCHHH
TDRLSDVAGVIGIEPKGSKSSQAERVIRKIE
HHHHHHHHHHEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]