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The map label for this gene is dapA [H]

Identifier: 52787194

GI number: 52787194

Start: 3341899

End: 3342801

Strand: Reverse

Name: dapA [H]

Synonym: BLi03503

Alternate gene names: 52787194

Gene position: 3342801-3341899 (Counterclockwise)

Preceding gene: 52787195

Following gene: 52787193

Centisome position: 79.16

GC content: 48.17

Gene sequence:

>903_bases
TTGAAAGTAGAGGGAATTATCCCTGCCATACTGACACCGCTTACAAAAGAACAGGCCTTTCATCCGGGCGCAGCCGAAAA
GCTGGTGAATCGTCTAATTGATTCAGGCGTCCATGGCATTTTTGCTTTAGGGACAAATGGCGAATTTCATTTATTCTCGC
AAGAGGAAAAGCTTCAAATTGCCGAAACAGTTGTAAAAGCGGTTAATAAACGAGTGCCTGTTTTCATCGGAGCAGGTGAA
AACAGTACTGAGGCGACCATTTCTTTATTCAATCAAATGGCGGATCTTGGAGCGGATGTTCTTTCGATTATTACGCCATA
CTTTGTTGCACCTTCGCAGGAGGAATTGTATCAGCATTTCCGCACGATTTCCGAAAATGTCGCGCTTCCTGTCCTGCTCT
ACAACATTCCGTCGAGAACAGGCGTATCATTGGAGCCCGAAACAGTTGAAAGGCTGGCGGCATTGCCGAACATCATCGGC
ATTAAGGACAGCAGCGGAAGCTTCGCCAATATTAAGGCGTATCTTGAGCGTACAAAAGAACAGTCCTTTTCCGTTCTGGC
AGGAACTGATTCGCTGATCTTAGACACATTGAAGGCGGGAGGGACAGGAGCTGTGGCTGCCACAGCCAATGTGTTTCCGC
ACACCGTTGTTTCAATCTATGAATCTTTTAAACAAGGAAACATTGAAGAGAGCGAGCACTATCAACAGCAGCTGCAGCCG
CTCCGTGATACGTTTTCACTCGGTTCACTGCCGGCGCCGCTAAAAAAAGCAGCGGAGCTTGCCGGCATCGACGTCGGACC
GCCTAAACGTCCGATTGCAGAACTGTCGGGAGAGCCGCTGCTAAAAGTGAAAAAGATGCTGGAAGGCTACGGAATTGAAG
CAAAACTGGCAAAGGAGCAGTAA

Upstream 100 bases:

>100_bases
AAAATGTTGCTTAATTAATCAAAACACCTTTATAATGAAATTTGAGAAAGCGTTTTACTATTTGATTGTTTAAAAATGCA
ACAGAAGGGAGCGAAGTCAC

Downstream 100 bases:

>100_bases
GATTATGAAAACGCTTTATCATTTTCGAACGGCCGCCCGAATTGAGGCTGGTCCACATTCACTCAATTTGCTCGGCGATT
ACTTAGATCAAATTGGATTG

Product: hypothetical protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKVEGIIPAILTPLTKEQAFHPGAAEKLVNRLIDSGVHGIFALGTNGEFHLFSQEEKLQIAETVVKAVNKRVPVFIGAGE
NSTEATISLFNQMADLGADVLSIITPYFVAPSQEELYQHFRTISENVALPVLLYNIPSRTGVSLEPETVERLAALPNIIG
IKDSSGSFANIKAYLERTKEQSFSVLAGTDSLILDTLKAGGTGAVAATANVFPHTVVSIYESFKQGNIEESEHYQQQLQP
LRDTFSLGSLPAPLKKAAELAGIDVGPPKRPIAELSGEPLLKVKKMLEGYGIEAKLAKEQ

Sequences:

>Translated_300_residues
MKVEGIIPAILTPLTKEQAFHPGAAEKLVNRLIDSGVHGIFALGTNGEFHLFSQEEKLQIAETVVKAVNKRVPVFIGAGE
NSTEATISLFNQMADLGADVLSIITPYFVAPSQEELYQHFRTISENVALPVLLYNIPSRTGVSLEPETVERLAALPNIIG
IKDSSGSFANIKAYLERTKEQSFSVLAGTDSLILDTLKAGGTGAVAATANVFPHTVVSIYESFKQGNIEESEHYQQQLQP
LRDTFSLGSLPAPLKKAAELAGIDVGPPKRPIAELSGEPLLKVKKMLEGYGIEAKLAKEQ
>Mature_300_residues
MKVEGIIPAILTPLTKEQAFHPGAAEKLVNRLIDSGVHGIFALGTNGEFHLFSQEEKLQIAETVVKAVNKRVPVFIGAGE
NSTEATISLFNQMADLGADVLSIITPYFVAPSQEELYQHFRTISENVALPVLLYNIPSRTGVSLEPETVERLAALPNIIG
IKDSSGSFANIKAYLERTKEQSFSVLAGTDSLILDTLKAGGTGAVAATANVFPHTVVSIYESFKQGNIEESEHYQQQLQP
LRDTFSLGSLPAPLKKAAELAGIDVGPPKRPIAELSGEPLLKVKKMLEGYGIEAKLAKEQ

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=279, Percent_Identity=30.8243727598566, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI13540533, Length=285, Percent_Identity=29.8245614035088, Blast_Score=115, Evalue=5e-26,
Organism=Escherichia coli, GI1788823, Length=259, Percent_Identity=35.5212355212355, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786463, Length=279, Percent_Identity=35.84229390681, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI87082415, Length=296, Percent_Identity=34.4594594594595, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1789620, Length=242, Percent_Identity=26.8595041322314, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32348; Mature: 32348

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00666 DHDPS_2 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVEGIIPAILTPLTKEQAFHPGAAEKLVNRLIDSGVHGIFALGTNGEFHLFSQEEKLQI
CCCCCCHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHH
AETVVKAVNKRVPVFIGAGENSTEATISLFNQMADLGADVLSIITPYFVAPSQEELYQHF
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RTISENVALPVLLYNIPSRTGVSLEPETVERLAALPNIIGIKDSSGSFANIKAYLERTKE
HHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
QSFSVLAGTDSLILDTLKAGGTGAVAATANVFPHTVVSIYESFKQGNIEESEHYQQQLQP
HCCEEEECCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LRDTFSLGSLPAPLKKAAELAGIDVGPPKRPIAELSGEPLLKVKKMLEGYGIEAKLAKEQ
HHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCEECCCCC
>Mature Secondary Structure
MKVEGIIPAILTPLTKEQAFHPGAAEKLVNRLIDSGVHGIFALGTNGEFHLFSQEEKLQI
CCCCCCHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHHHH
AETVVKAVNKRVPVFIGAGENSTEATISLFNQMADLGADVLSIITPYFVAPSQEELYQHF
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RTISENVALPVLLYNIPSRTGVSLEPETVERLAALPNIIGIKDSSGSFANIKAYLERTKE
HHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
QSFSVLAGTDSLILDTLKAGGTGAVAATANVFPHTVVSIYESFKQGNIEESEHYQQQLQP
HCCEEEECCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LRDTFSLGSLPAPLKKAAELAGIDVGPPKRPIAELSGEPLLKVKKMLEGYGIEAKLAKEQ
HHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]